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Non-Coding RNA, Volume 3, Issue 2

June 2017 - 6 articles

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Articles (6)

  • Article
  • Open Access
23 Citations
6,441 Views
20 Pages

Detecting Disease Specific Pathway Substructures through an Integrated Systems Biology Approach

  • Salvatore Alaimo,
  • Gioacchino Paolo Marceca,
  • Alfredo Ferro and
  • Alfredo Pulvirenti

In the era of network medicine, pathway analysis methods play a central role in the prediction of phenotype from high throughput experiments. In this paper, we present a network-based systems biology approach capable of extracting disease-perturbed s...

  • Article
  • Open Access
13 Citations
6,043 Views
17 Pages

Deciphering microRNAs and Their Associated Hairpin Precursors in a Non-Model Plant, Abelmoschus esculentus

  • Kavitha Velayudha Vimala Kumar,
  • Nagesh Srikakulam,
  • Priyavathi Padbhanabhan and
  • Gopal Pandi

MicroRNAs (miRNAs) are crucial regulatory RNAs, originated from hairpin precursors. For the past decade, researchers have been focusing extensively on miRNA profiles in various plants. However, there have been few studies on the global profiling of p...

  • Article
  • Open Access
10 Citations
5,486 Views
20 Pages

Recently, a novel type of non-coding RNA (ncRNA), known as ncRNA fragments or ncRFs, has been characterised in various organisms, including plants. The biogenesis mechanism, function and abundance of ncRFs stemming from various ncRNAs are poorly unde...

  • Article
  • Open Access
45 Citations
6,023 Views
12 Pages

Assessment of isomiR Discrimination Using Commercial qPCR Methods

  • Rogan Magee,
  • Aristeidis G. Telonis,
  • Tess Cherlin,
  • Isidore Rigoutsos and
  • Eric Londin

We sought to determine whether commercial quantitative polymerase chain reaction (qPCR) methods are capable of distinguishing isomiRs: variants of mature microRNAs (miRNAs) with sequence endpoint differences. We used two commercially available miRNA...

  • Article
  • Open Access
55 Citations
10,811 Views
22 Pages

Present Scenario of Long Non-Coding RNAs in Plants

  • Garima Bhatia,
  • Neetu Goyal,
  • Shailesh Sharma,
  • Santosh Kumar Upadhyay and
  • Kashmir Singh

Small non-coding RNAs have been extensively studied in plants over the last decade. In contrast, genome-wide identification of plant long non-coding RNAs (lncRNAs) has recently gained momentum. LncRNAs are now being recognized as important players in...

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Non-Coding RNA - ISSN 2311-553X