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Journal of Fungi, Volume 5, Issue 1

March 2019 - 26 articles

Cover Story: Candida albicans yeast cells can be induced to form hyphae by many well-studied environmental stimuli. However, internal signals, such as inhibition of proliferation, can also affect hyphal morphogenesis. Shown here are colonies of a C. albicans cdc4 mutant that grows constitutively as hyphae due to a combination of cell cycle inhibition and transcription factor stabilization. In the accompanying article, the role of endogenous signals in the regulation of hyphal morphogenesis is reviewed. View this paper.
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Articles (26)

  • Review
  • Open Access
29 Citations
5,169 Views
12 Pages

Mucormycosis in Burn Patients

  • Pauline Devauchelle,
  • Mathieu Jeanne and
  • Emilie Fréalle

21 March 2019

Patients with extensive burns are an important group at risk for cutaneous mucormycosis. This study aimed to perform a systematic review of all reported mucormycosis cases in burn patients from 1990 onward. A Medline search yielded identification of...

  • Review
  • Open Access
662 Citations
25,503 Views
19 Pages

Global Epidemiology of Mucormycosis

  • Hariprasath Prakash and
  • Arunaloke Chakrabarti

21 March 2019

Mucormycosis is an angio-invasive fungal infection, associated with high morbidity and mortality. A change in the epidemiology of mucormycosis has been observed in recent years with the rise in incidence, new causative agents and susceptible populati...

  • Review
  • Open Access
90 Citations
6,966 Views
8 Pages

Molecular Strategies to Diagnose Mucormycosis

  • Laurence Millon,
  • Emeline Scherer,
  • Steffi Rocchi and
  • Anne-Pauline Bellanger

20 March 2019

Molecular techniques have provided a new understanding of the epidemiology of mucormycosis and improved the diagnosis and therapeutic management of this life-threatening disease. PCR amplification and sequencing were first applied to better identify...

  • Review
  • Open Access
110 Citations
10,690 Views
9 Pages

Disease Entities in Mucormycosis

  • Alexandra Serris,
  • François Danion and
  • Fanny Lanternier

14 March 2019

Mucormycosis is an emerging life-threatening fungal infection caused by Mucorales. This infection occurs mainly in immunocompromised patients, especially with hematological malignancy, transplantation, or diabetes mellitus. Rhino-orbito-cerebral and...

  • Article
  • Open Access
14 Citations
4,639 Views
13 Pages

Candida albicans Morphology-Dependent Host FGF-2 Response as a Potential Therapeutic Target

  • Sandeep Vellanki,
  • Eun Young Huh,
  • Stephen P. Saville and
  • Soo Chan Lee

5 March 2019

Angiogenesis mediated by proteins such as Fibroblast Growth Factor-2 (FGF-2) is a vital component of normal physiological processes and has also been implicated in contributing to the disease state associated with various microbial infections. Previo...

  • Review
  • Open Access
84 Citations
12,180 Views
15 Pages

28 February 2019

Candida albicans is a human commensal fungus that is able to assume several morphologies, including yeast, hyphal, and pseudohyphal. Under a range of conditions, C. albicans performs a regulated switch to the filamentous morphology, characterized by...

  • Article
  • Open Access
14 Citations
4,403 Views
8 Pages

Chronic Pulmonary Aspergillosis in Patients with Underlying Respiratory Disorders in Cuba—A Pilot Study

  • Nathalie Beltrán Rodríguez,
  • Javier Luis San Juan-Galán,
  • Carlos Manuel Fernández Andreu,
  • Dulce María Yera,
  • Miriam Barrios Pita,
  • Mayda Rosa Perurena Lancha,
  • Rosario Esperanza Velar Martínez,
  • María Teresa Illnait Zaragozí and
  • Gerardo Félix Martínez Machín

22 February 2019

Chronic pulmonary aspergillosis (CPA) is a fungal infection with high mortality and morbidity rates. This disease is caused by several Aspergillus species and affects patients with an underlying respiratory condition. This pilot study aims to recogni...

  • Article
  • Open Access
24 Citations
4,354 Views
8 Pages

Changing Epidemiology of Invasive Candidiasis in Children during a 10-Year Period

  • Maria Noni,
  • Angeliki Stathi,
  • Ilia Vaki,
  • Aristea Velegraki,
  • Levantia Zachariadou and
  • Athanasios Michos

22 February 2019

Candida species are a common cause of invasive infection in neonates and children. The aim of our study was to evaluate the epidemiology and microbiology of invasive candidiasis (IC) in the largest tertiary Greek pediatric hospital during a 10-year p...

  • Review
  • Open Access
52 Citations
10,170 Views
10 Pages

22 February 2019

Onychomycosis is mainly caused by two dermatophyte species, Trichophyton rubrum and Trichophyton interdigitale. A study of nail invasion mechanisms revealed that the secreted subtilisin Sub6, which has never been detected under in vitro growth condit...

  • Review
  • Open Access
54 Citations
10,422 Views
28 Pages

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

  • Jehoshua Sharma,
  • Sierra Rosiana,
  • Iqra Razzaq and
  • Rebecca S. Shapiro

21 February 2019

Fungal infections are a growing public health concern, and an increasingly important cause of human mortality, with Candida species being amongst the most frequently encountered of these opportunistic fungal pathogens. Several Candida species are pol...

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J. Fungi - ISSN 2309-608X