Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review
Abstract
:1. Introduction
2. Material and Methods
2.1. Search Strategy
2.2. Statistical Analysis
3. Results and Discussion
3.1. Paracoccidioidomycosis and HIV Infection
3.2. Paracoccidioidomycosis and Solid Organ Malignancies
3.3. Paracoccidioidomycosis and Hematologic Malignancies
3.4. Paracoccidioidomycosis and Solid Organ Transplant
3.5. Paracoccidioidomycosis and Immunotherapies
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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PCM and HIV (%) | PCM (%) | p Value | |
---|---|---|---|
Clinical Data | |||
Fever | 82.7 | 35.4 ** | <0.001 |
Lymphadenopathy | 72.9 # | 50.6 * | <0.001 |
Splenomegaly | 22.6 | 4.7 * | <0.001 |
Skin Lesions | 58.9 | 29.6 * | <0.001 |
Pneumopathy | 70.3 | 63.8 * | 0.15 |
Oral mucosa | 29 | 50 * | <0.001 |
Laboratory data (positivity rates) | |||
Direct microscopy | 57.4 | 44 ** | 0.052 |
Culture | 42.2 | 25.3 * | <0.001 |
Histopathology | 94.5 | 64.7 * | <0.001 |
Serology | 74.6 | 97.2 * | <0.001 |
Outcomes | |||
Relapse rates | 11 | 8.2 ** | 0.48 |
Mortality rates | 35 | 7.9 ** | <0.001 |
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De Almeida Jr., J.N.; Peçanha-Pietrobom, P.M.; Colombo, A.L. Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review. J. Fungi 2019, 5, 2. https://doi.org/10.3390/jof5010002
De Almeida Jr. JN, Peçanha-Pietrobom PM, Colombo AL. Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review. Journal of Fungi. 2019; 5(1):2. https://doi.org/10.3390/jof5010002
Chicago/Turabian StyleDe Almeida Jr., João N., Paula M. Peçanha-Pietrobom, and Arnaldo L. Colombo. 2019. "Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review" Journal of Fungi 5, no. 1: 2. https://doi.org/10.3390/jof5010002
APA StyleDe Almeida Jr., J. N., Peçanha-Pietrobom, P. M., & Colombo, A. L. (2019). Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review. Journal of Fungi, 5(1), 2. https://doi.org/10.3390/jof5010002