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Journal of Fungi, Volume 5, Issue 2

June 2019 - 27 articles

Cover Story: Low virulence Candida species can provide protection against lethal polymicrobial sepsis caused by Candida albicans and Staphylococcus aureus. We postulate that this protection is mediated by myeloid-derived suppressor cells (MDSCs) that expand in the bone marrow after primary (1˚) intraperitoneal challenge and are activated after a secondary (2˚) lethal challenge. This beneficial innate response, termed trained tolerogenic immunity, represents a novel form of trained innate immunity. View this paper.
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Articles (27)

  • Article
  • Open Access
13 Citations
4,515 Views
17 Pages

20 June 2019

Biocontrol of the mycotoxin aflatoxin utilizes non-aflatoxigenic strains of Aspergillus flavus, which have variable success rates as biocontrol agents. One non-aflatoxigenic strain, NRRL 35739, is a notably poor biocontrol agent. Its growth in artifi...

  • Commentary
  • Open Access
30 Citations
4,526 Views
6 Pages

The Fight against HIV-Associated Disseminated Histoplasmosis in the Americas: Unfolding the Different Stories of Four Centers

  • Mathieu Nacher,
  • Terezinha Silva Leitao,
  • Beatriz L. Gómez,
  • Pierre Couppié,
  • Antoine Adenis,
  • Lisandra Damasceno,
  • Magalie Demar,
  • Blanca Samayoa,
  • Diego H. Cáceres and
  • Roger Pradinaud
  • + 3 authors

17 June 2019

Disseminated histoplasmosis is a major opportunistic infection of HIV-infected patients, killing thousands in Latin America each year. Yet, it remains a neglected disease that is often confused with tuberculosis, for lack of simple, affordable, and r...

  • Review
  • Open Access
51 Citations
8,391 Views
15 Pages

Mass Spectrometry-Based Proteomics of Fungal Pathogenesis, Host–Fungal Interactions, and Antifungal Development

  • Brianna Ball,
  • Arianne Bermas,
  • Duncan Carruthers-Lay and
  • Jennifer Geddes-McAlister

17 June 2019

The prevalence of fungal diseases is increasing on a global scale, ranging from acute to systemic infections caused by commensal or pathogenic microorganisms, often associated with the immune status of the host. Morbidity and mortality rates remain h...

  • Review
  • Open Access
18 Citations
8,512 Views
13 Pages

14 June 2019

Microbes typically exist in mixed communities and display complex synergistic and antagonistic interactions. The Type VI secretion system (T6SS) is widespread in Gram-negative bacteria and represents a contractile nano-machine that can fire effector...

  • Article
  • Open Access
37 Citations
6,498 Views
21 Pages

Integrated Analysis of Clinical and Microbiome Risk Factors Associated with the Development of Oral Candidiasis during Cancer Chemotherapy

  • Patricia I. Diaz,
  • Bo-Young Hong,
  • Amanda K. Dupuy,
  • Linda Choquette,
  • Angela Thompson,
  • Andrew L. Salner,
  • Peter K. Schauer,
  • Upendra Hegde,
  • Joseph A. Burleson and
  • Linda D. Strausbaugh
  • + 2 authors

13 June 2019

Oral candidiasis is a common side effect of cancer chemotherapy. To better understand predisposing factors, we followed forty-five subjects who received 5-fluorouracil- or doxorubicin-based treatment, during one chemotherapy cycle. Subjects were eval...

  • Review
  • Open Access
60 Citations
7,862 Views
20 Pages

12 June 2019

Aspergillus fumigatus and Pseudomonas aeruginosa are central fungal and bacterial members of the pulmonary microbiota. The interactions between A. fumigatus and P. aeruginosa have only just begun to be explored. A balance between inhibitory and stimu...

  • Article
  • Open Access
8 Citations
4,141 Views
8 Pages

Accuracy of Buffy Coat in the Diagnosis of Disseminated Histoplasmosis in AIDS-Patients in an Endemic Area of Brazil

  • Terezinha M. J. Silva Leitão,
  • Antonio M. P. Oliveira Filho,
  • José Evaldo P. Sousa Filho,
  • Bruno M. Tavares,
  • Jacó R. L. Mesquita,
  • Luís Arthur B. G. Farias,
  • Rosa S. Mota,
  • Mathieu Nacher and
  • Lisandra S. Damasceno

9 June 2019

The buffy coat is obtained routinely for disseminated histoplamosis (DH) diagnosis in Ceará, Brazil. The aim of this study is to describe the accuracy of staining smears for Histoplasma in the buffy coat of AIDS-patients with DH. From 2012&nda...

  • Communication
  • Open Access
5 Citations
5,144 Views
14 Pages

Influence of Environmental Growth Factors on the Biomass and Pigment Production of Chlorociboria aeruginascens

  • Stephanie Stange,
  • Susanne Steudler,
  • Hubertus Delenk,
  • Anett Werner,
  • Thomas Walther and
  • André Wagenführ

8 June 2019

The soft rot fungus Chlorociboria aeruginascens produces a blue–green pigment xylindein, which is of considerable interest for various applications such as in the veneer industry or in organic semiconductors. To understand the fungal growth as...

  • Review
  • Open Access
14 Citations
7,256 Views
11 Pages

5 June 2019

The fungal pathogen Histoplasma capsulatum resides within the phagosome of host phagocytic cells. Within this intracellular compartment, Histoplasma yeast replication requires the acquisition of several essential nutrients, including metal ions. Rece...

  • Article
  • Open Access
3 Citations
4,274 Views
8 Pages

Does Online Search Behavior Coincide with Candida auris Cases? An Exploratory Study

  • Katja Saris,
  • Jacques F. Meis,
  • Jesús Rodriguez Baño,
  • Evelina Tacconelli,
  • Tom H. van de Belt and
  • Andreas Voss

4 June 2019

Candida auris is an emerging multidrug resistant infectious yeast which is challenging to eradicate and despite available laboratory methods is still difficult to identify especially in less developed countries. To limit the rapid spread of C. auris,...

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J. Fungi - ISSN 2309-608X