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Journal of Cardiovascular Development and Disease, Volume 10, Issue 6

June 2023 - 40 articles

Cover Story: Skidmore et al. discuss the challenges and potential solutions for treating congenital heart disease with valve dysfunction in babies. Partial heart transplantation involves transplanting only the valves of a donor heart into the recipient. This procedure offers the potential for growth and long-term success of the transplanted valves. The authors used rodent models to evaluate the efficacy of heterotopic partial heart transplants. They transplanted aortic heart valves into the abdominal aortic position and aortic valve leaflets into the renal subcapsular space in rodents. The ultimate goal is to demonstrate the success of this procedure in larger, more comparable models to humans, aiming to enhance outcomes and quality of life for patients with congenital valve dysfunction. View this paper
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Articles (40)

  • Article
  • Open Access
3 Citations
3,493 Views
12 Pages

Antiplatelet agents are commonly used in combination with proton-pump inhibitors (PPIs) in patients with acute coronary syndrome who are at risk of gastrointestinal hemorrhage. However, studies have reported that PPIs can alter the pharmacokinetics o...

  • Article
  • Open Access
3 Citations
3,582 Views
15 Pages

Postoperative Weight Gain within Enhanced Recovery after Cardiac Surgery

  • Alexandra Krüger,
  • Anna Flo Forner,
  • Jörg Ender,
  • Aniruddha Janai,
  • Youssef Roufail,
  • Wolfgang Otto,
  • Massimiliano Meineri and
  • Waseem Z. A. Zakhary

Optimal fluid therapy during perioperative care as part of enhanced recovery after cardiac surgery (ERACS) should improve the outcome. Our objective was finding out the effects of fluid overload on outcome and mortality within a well-established ERAC...

  • Article
  • Open Access
4 Citations
2,225 Views
13 Pages

The activation of pulmonary adventitial fibroblasts (PAFs) is one of the key components of pulmonary arterial remodelling in pulmonary arterial hypertension (PAH). Emerging evidence indicates that lncRNAs may play fibrotic roles in a range of disease...

  • Article
  • Open Access
37 Citations
5,426 Views
15 Pages

Left Atrial Strain Imaging by Speckle Tracking Echocardiography: The Supportive Diagnostic Value in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

  • Ines Paola Monte,
  • Denise Cristiana Faro,
  • Giancarlo Trimarchi,
  • Fabrizio de Gaetano,
  • Mariapaola Campisi,
  • Valentina Losi,
  • Lucio Teresi,
  • Gianluca Di Bella,
  • Corrado Tamburino and
  • Cesare de Gregorio

Background: Left atrial (LA) function is crucial for assessing left ventricular filling in various cardiovascular conditions. Cardiac Amyloidosis (CA) is characterized by atrial myopathy and LA function impairment, with diastolic dysfunction up to re...

  • Review
  • Open Access
10 Citations
4,529 Views
16 Pages

Effects of Lipid Lowering Therapies on Vulnerable Plaque Features: An Updated Narrative Review of the Literature

  • Flavio Giuseppe Biccirè,
  • Laura Gatto,
  • Ylenia La Porta,
  • Pasquale Pignatelli,
  • Francesco Prati and
  • Daniele Pastori

The clinical evidence on the efficacy of lipid lowering therapy in patients with coronary artery disease (CAD) is unequivocally established. However, the effects of these therapies on plaque composition and stability are less clear. The use of intrac...

  • Article
  • Open Access
2 Citations
2,134 Views
12 Pages

A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction

  • Zsuzsanna Mihály,
  • Samuel Booth,
  • Dat Tin Nguyen,
  • Milán Vecsey-Nagy,
  • Miklós Vértes,
  • Zsófia Czinege,
  • Csongor Péter,
  • Péter Sótonyi and
  • Andrea Varga

(1) Study purpose: The aim of our prospective single-center, matched case–control study was to compare the number and volume of acute ischemic brain lesions following carotid endarterectomy (CEA) versus carotid artery stenting (CAS) using a pro...

  • Review
  • Open Access
15 Citations
4,903 Views
13 Pages

Invasive and Non-Invasive Diagnostic Pathways in the Diagnosis of Cardiac Amyloidosis

  • Alexandros Briasoulis,
  • Dimitrios Bampatsias,
  • Adamantia Papamichail,
  • Toshiki Kuno,
  • John Skoularigis,
  • Andrew Xanthopoulos and
  • Filippos Triposkiadis

The appropriate diagnosis and subtyping of cardiac amyloidosis (CA) is frequently missed or delayed due to its vague presentation, clinical overlapping, and diagnostic pitfalls. Recent developments in both invasive and non-invasive diagnostic techniq...

  • Review
  • Open Access
5 Citations
6,096 Views
11 Pages

The Complex but Fascinating Relationship between Sport and Atrial Fibrillation: From Pathophysiology to the Clinical Scenario

  • Mario Tatangelo,
  • Marco Rebecchi,
  • Marianna Sgueglia,
  • Alessandra Colella,
  • Cinzia Crescenzi,
  • Germana Panattoni,
  • Pellegrino Ciampi,
  • Oreste Lanza,
  • Emanuele Canali and
  • Leonardo Calò

Atrial fibrillation (AF) is the most common cause of hospital admission among all arrhythmias in the general population. Moreover, AF represents the most common arrhythmia in the athletic population as well. The complex but fascinating relationship b...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425