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Processes, Volume 7, Issue 3

March 2019 - 59 articles

Cover Story: Podocyte cells wrap around blood vessels in the kidney and play a key role in the progression of diabetic kidney disease (DKD). Podocytes prompt a glucose-stimulated local renin-angiotensin system (RAS) that produces angiotensin II (ANG II). ACE inhibition is a pharmaceutical approach to suppress ANG II and slow DKD progression. A PK/PD model for ACE inhibition in a local RAS network in a podocyte has been developed and compared with a systemic RAS model. The model is parameterized for normal and impaired renal function and can consider subject-specific glucose dynamics as input, enabling the study of various pathophysiological conditions. View this paper.
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Articles (59)

  • Article
  • Open Access
2 Citations
4,279 Views
15 Pages

26 March 2019

Global Sensitivity Analysis (GSA) is a technique that numerically evaluates the significance of model parameters with the aim of reducing the number of parameters that need to be estimated accurately from experimental data. In the work presented here...

  • Feature Paper
  • Article
  • Open Access
11 Citations
4,509 Views
17 Pages

A Novel Multiphase Methodology Simulating Three Phase Flows in a Steel Ladle

  • Marco A. Ramírez-Argáez,
  • Abhishek Dutta,
  • A. Amaro-Villeda,
  • C. González-Rivera and
  • A. N. Conejo

26 March 2019

Mixing phenomena in metallurgical steel ladles by bottom gas injection involves three phases namely, liquid molten steel, liquid slag and gaseous argon. In order to numerically solve this three-phase fluid flow system, a new approach is proposed whic...

  • Article
  • Open Access
10 Citations
5,493 Views
37 Pages

26 March 2019

This study investigates the process of how the original equipment manufacturers (OEMs) in automobile and consumer electronics industries design their supply networks. In contrast to the sociological viewpoint, which regards the emergence of networks...

  • Article
  • Open Access
18 Citations
5,588 Views
14 Pages

26 March 2019

The prediction of mold level is a basic and key problem of continuous casting production control. Many current techniques fail to predict the mold level because of mold level is non-linear, non-stationary and does not have a normal distribution. A hy...

  • Article
  • Open Access
19 Citations
4,488 Views
13 Pages

25 March 2019

Carbonaceous adsorbents with both high sulfur capacity and easy regeneration are required for flue gas desulfurization. A hierarchical structure is desirable for SO2 removal, since the micropores are beneficial for SO2 adsorption, while the mesopore...

  • Article
  • Open Access
27 Citations
6,083 Views
17 Pages

Novel Deep Eutectic Solvent Based on Levulinic Acid and 1,4-Butanediol as an Extraction Media for Bioactive Alkaloid Rutaecarpine

  • Yue-Yue Si,
  • Shi-Wei Sun,
  • Kun Liu,
  • Yang Liu,
  • Hai-Lin Shi,
  • Ke Zhao,
  • Jin Wang and
  • Wei Wang

24 March 2019

Deep eutectic solvents (DESs) are increasingly receiving interest as a new type of green and sustainable alternative to hazardous organic solvents. In this work, a novel DES based on levulinic acid (La) and 1,4-butanediol (Buta) as an extraction medi...

  • Article
  • Open Access
10 Citations
4,935 Views
18 Pages

24 March 2019

Intelligent data analytics-based cloud computing is a leading trend for managing a large-scale network in contemporary manufacturing environments. The data and information are shared using the cloud environments and valuable knowledge is driven using...

  • Article
  • Open Access
4 Citations
4,442 Views
14 Pages

A Novel Robust Method for Solving CMB Receptor Model Based on Enhanced Sampling Monte Carlo Simulation

  • Wen Hou,
  • Yunlei Yang,
  • Zheng Wang,
  • Muzhou Hou,
  • Qianhong Wu and
  • Xiaoliang Xie

23 March 2019

The traditional effective variance weighted least squares algorithms for solving CMB (Chemical Mass Balance) models have the following drawbacks: When there is collinearity among the sources or the number of species is less than the number of sources...

  • Feature Paper
  • Article
  • Open Access
24 Citations
5,766 Views
23 Pages

23 March 2019

Developing the so-called grey box or hybrid models of limited complexity for process systems is the cornerstone in advanced control and real-time optimization routines. These models must be based on fundamental principles and customized with sub-mode...

  • Article
  • Open Access
68 Citations
6,825 Views
16 Pages

Effect of Nitric Acid Modification on Characteristics and Adsorption Properties of Lignite

  • Bo Huang,
  • Guowei Liu,
  • Penghui Wang,
  • Xiang Zhao and
  • Hongxiang Xu

22 March 2019

The objective of this research was to explore the changes of the pore structure and surface properties of nitric-modified lignite and base the adsorption performance on physical and chemical adsorbent characteristics. To systematically evaluate pore...

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Processes - ISSN 2227-9717