Biomedicines, Volume 7, Issue 2 (June 2019) – 23 articles
Cover Story (view full-size image): From static models in microtiter plates to dynamic models in flow cells, multiple systems have been developed to study the growth and susceptibility of biofilms to antimicrobials. In static systems, bacterial growth in media has a finite supply of nutrients, while in dynamic systems the nutrients are continually refreshed by the flow of sterile media. To resemble the physiological conditions of biofilm-infected chronic wounds, in vitro biofilm models aim to incorporate multiple clinically relevant wound microorganisms and simulate the composition of the wound exudate and wound bed. View this paper.
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