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Open AccessReview

Oral and Psychological Alterations in Haemophiliac Patients

Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina, Italy
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80121 Naples, Italy
Department of Surgical and Biomedical Sciences, Catania University, 95123 Catania, Italy
Department of Maxillofacial Surgery, Loma Linda University, Loma Linda, CA 92354, USA
Author to whom correspondence should be addressed.
Biomedicines 2019, 7(2), 33;
Received: 8 April 2019 / Revised: 17 April 2019 / Accepted: 19 April 2019 / Published: 20 April 2019
Haemophiliacs are hereditary coagulopathies whose basic anomaly consists of the quantitative or qualitative alteration of one or more plasma proteins in the coagulation system. The objective of this review is to analyse all risk factors, predispositions and alterations to the oral-maxillofacial district in patients with haemophilia. The broader assessment also includes the psychological aspects that could affect the treatment and maintenance of oral conditions. The study takes into consideration all the works in the literature in the last 10 years. Works that present oral, dental and psychological changes in haemophilia patients have been combined. A total of 16 studies were analysed carefully evaluating and explaining all the alterations and risk factors that this disease provides. The aim of the review is to report all the anomalies reported in the literature for these patients, and to direct and update the clinician in the treatment of haemophilia patients. View Full-Text
Keywords: haemophilia; oral alterations; dental risk factor; psychological conditions haemophilia; oral alterations; dental risk factor; psychological conditions
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Fiorillo, L.; De Stefano, R.; Cervino, G.; Crimi, S.; Bianchi, A.; Campagna, P.; Herford, A.S.; Laino, L.; Cicciù, M. Oral and Psychological Alterations in Haemophiliac Patients. Biomedicines 2019, 7, 33.

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