Evaluation of Angiogenesis Assays
AbstractAngiogenesis assays allow for the evaluation of pro- or anti-angiogenic activity of endogenous or exogenous factors (stimulus or inhibitors) through investigation of their pro-or anti- proliferative, migratory, and tube formation effects on endothelial cells. To model the process of angiogenesis and the effects of biomolecules on that process, both in vitro and in vivo methods are currently used. In general, in vitro methods monitor specific stages in the angiogenesis process and are used for early evaluations, while in vivo methods more accurately simulate the living microenvironment to provide more pertinent information. We review here the current state of angiogenesis assays as well as their mechanisms, advantages, and limitations. View Full-Text
Share & Cite This Article
Stryker, Z.I.; Rajabi, M.; Davis, P.J.; Mousa, S.A. Evaluation of Angiogenesis Assays. Biomedicines 2019, 7, 37.
Stryker ZI, Rajabi M, Davis PJ, Mousa SA. Evaluation of Angiogenesis Assays. Biomedicines. 2019; 7(2):37.Chicago/Turabian Style
Stryker, Zachary I.; Rajabi, Mehdi; Davis, Paul J.; Mousa, Shaker A. 2019. "Evaluation of Angiogenesis Assays." Biomedicines 7, no. 2: 37.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.