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Biomedicines, Volume 2, Issue 3

September 2014 - 2 articles

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Review

8 Citations

11,380 Views

18 Pages

Lentivirus-Induced Dendritic Cells (iDC) for Immune-Regenerative Therapies in Cancer and Stem Cell Transplantation

Renata Stripecke

Biomedicines2014, 2(3), 229-246;https://doi.org/10.3390/biomedicines2030229

21 August 2014

Conventional dendritic cells (cDC) are ex vivo differentiated professional antigen presenting cells capable of potently stimulating naïve T cells and with vast potential for immunotherapeutic applications. The manufacture of clinical-grade cDC is rel...

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Review

37 Citations

10,385 Views

18 Pages

Toll-Like Receptor 9 Agonists for Cancer Therapy

Davide Melisi,
Melissa Frizziero,
Anna Tamburrino,
Marco Zanotto,
Carmine Carbone,
Geny Piro and
Giampaolo Tortora

Biomedicines2014, 2(3), 211-228;https://doi.org/10.3390/biomedicines2030211

4 August 2014

The immune system has acquired increasing importance as a key player in cancer maintenance and growth. Thus, modulating anti-tumor immune mediators has become an attractive strategy for cancer treatment. Toll-like receptors (TLRs) have gradually emer...

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Biomedicines - ISSN 2227-9059

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