Plants, Volume 12, Issue 20
2023 October-2 - 147 articles
Cover Story: Arnica montana L. flowers are used to treat blunt injuries, traumas, inflammatory and rheumatic conditions. The main bioactive constituents are sesquiterpene lactones (STLs), esters of helenalin (HEL) and 11α,13-dihydrohelenalin (DH). In pharmacological studies, HEL derivatives were usually more potent. Big differences in the STL pattern occur between the drug from Central/Eastern Europe and the one from Spain. In the former, HEL esters predominate; the latter contains higher amounts of DH derivatives. It has also been proposed to distinguish two subspecies, subsp. montana (Central/Eastern Europe) and subsp. atlantica (Iberian Peninsula). This review tries to answer the question as to whether the geographical origin of Arnica montana flowers is of relevance for their medicinal and pharmaceutical quality. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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