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Scientia Pharmaceutica, Volume 89, Issue 1

March 2021 - 14 articles

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Articles (14)

  • Article
  • Open Access
9 Citations
6,991 Views
12 Pages

Asenapine maleate is an antipsychotic drug that is indicated in the treatment of schizophrenia and bipolar disorders. It has low aqueous solubility and high permeability (Class II drug) and undergoes an extensive first pass effect. These problems res...

  • Article
  • Open Access
6 Citations
5,137 Views
12 Pages

Background: Even though, Pseudomonas aeruginosa is a common cause of hospital-acquired infections, treatment is challenging because of decreasing rates of susceptibility to many broad-spectrum antibiotics. Methods: Consumption data of eight broad spe...

  • Article
  • Open Access
8 Citations
5,860 Views
11 Pages

25 February 2021

Malignant melanoma is the major cause of skin cancer-related deaths. Surgery in combination with radiotherapy, immunotherapy or chemotherapy is used to eradicate cancer cells, however, this treatment option is limited by the tolerance of the surround...

  • Review
  • Open Access
13 Citations
9,729 Views
11 Pages

The Potential Role of Lithium as an Antiviral Agent against SARS-CoV-2 via Membrane Depolarization: Review and Hypothesis

  • Abdallah Barjas Qaswal,
  • Aiman Suleiman,
  • Hasan Guzu,
  • Taima’a Harb and
  • Bashir Atiyat

15 February 2021

Studies on potential treatments of Coronavirus Disease 2019 (COVID-19) are important to improve the global situation in the face of the pandemic. This review proposes lithium as a potential drug to treat COVID-19. Our hypothesis states that lithium c...

  • Article
  • Open Access
4 Citations
4,945 Views
11 Pages

5 February 2021

Bacteria have acquired resistance against almost all antibiotics because of the misuse of antibacterial agents and long periods of treatment. Antimicrobial peptides (AMPs) are one of the most encouraging candidates to solve this problem, as they poss...

  • Article
  • Open Access
4 Citations
7,346 Views
13 Pages

Development and Validation of a Rapid Analytical Method for the Simultaneous Quantification of Metabolic Syndrome Drugs by HPLC-DAD Chromatography

  • Jorge Cruz-Angeles,
  • Luz María Martínez,
  • Marcelo Videa,
  • José Rodríguez-Rodríguez and
  • Cecilia Martínez-Jiménez

Worldwide, 25% of the population suffers from metabolic syndrome (MetS). The treatment of patients with MetS regularly includes drugs prescribed simultaneously to treat several disorders that manifest at the same time, such as hypercholesterolemia, a...

  • Review
  • Open Access
8 Citations
7,952 Views
14 Pages

Porophyllum Genus Compounds and Pharmacological Activities: A Review

  • María José Vázquez-Atanacio,
  • Mirandeli Bautista-Ávila,
  • Claudia Velázquez-González,
  • Araceli Castañeda-Ovando,
  • Manasés González-Cortazar,
  • Carolina Guadalupe Sosa-Gutiérrez and
  • Deyanira Ojeda-Ramírez

The genus Porophyllum (family Asteraceae) is native to the western hemisphere, growing in tropical and subtropical North and South America. Mexico is an important center of diversification of the genus. Plants belong of genus Porophyllum have been us...

  • Review
  • Open Access
14 Citations
7,746 Views
14 Pages

Sedating Mechanically Ventilated COVID-19 Patients with Volatile Anesthetics: Insights on the Last-Minute Potential Weapons

  • Aiman Suleiman,
  • Abdallah Barjas Qaswal,
  • Mazen Alnouti,
  • Moh’d Yousef,
  • Bayan Suleiman,
  • Mohammad El Jarbeh,
  • Ghadeer Alshawabkeh,
  • Isam Bsisu,
  • Abeer Santarisi and
  • Muaweih Ababneh

Coronavirus Disease 2019 (COVID-19) has spread globally with the number of cases exceeding seventy million. Although trials on potential treatments of COVID-19 Acute Respiratory Distress Syndrome (ARDS) are promising, the introduction of an effective...

  • Review
  • Open Access
23 Citations
11,808 Views
14 Pages

Diabetes mellitus is a pathology with increasing frequency in society, being one of the main causes of death worldwide. For this reason, new therapeutic targets have been studied over the years. 11β-hydroxysteroid dehydrogenase type 1 (11β-...

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Sci. Pharm. - ISSN 2218-0532