Scientia Pharmaceutica, Volume 93, Issue 4

Injectable biostimulatory agents such as poly-L-lactic acid (PLLA), polycaprolactone (PCL), and calcium hydroxyapatite (CaHA) have emerged as key tools in regenerative aesthetics due to their ability to stimulate adipogenesis and adipocyte metabolic...

Over the last decade, additive manufacturing (AM) has been widely investigated for developing on-demand, patient-centric, and personalized medications. Among various AM techniques, fused deposition modeling (FDM), semi-solid extrusion (SSE), inkjet p...

In this study, a terminological and grammatical survey of essential and fatty oils of plant origin was performed in the selected Austrian, Hungarian, Spanish, and Belgian pharmacopoeias from the 18th to 19th centuries. The Latin-language prescription...

Biopharmaceuticals are medical drugs produced by means of biotechnology. In contrast with small-molecule (traditional) drugs, which are usually synthesized chemically, biopharmaceuticals are derived from biological sources, including tissues, cells,...

Docetaxel (DTX)-loaded polymeric nanoparticles composed of Eudragit RL and RS 100 were developed by solvent evaporation using D-α-tocopheryl polyethene glycol 1000 succinate as an emulsifier and optimised by Central Composite Design. The effect...

Benign prostatic hyperplasia (BPH) and prostatitis are multifactorial urological disorders associated with chronic inflammation, oxidative stress, and androgenic imbalance. Dysphania ambrosioides (L.) Mosyakin & Clemants contains flavonoids and p...

Bioactive ingredients are compounds, typically derived from natural sources, that provide specific health benefits or perform certain beneficial functions. Although they can play a role in maintaining good health, their effects can vary widely based...

Diabetes mellitus (DM) is a disease that affects over 537 million people worldwide and results in 6.7 million deaths annually. Conventional treatment of this disease focuses on lifestyle changes and drug administration. However, very few people can a...

Radiotherapy (RT) is a standard treatment for cervical cancer, but its efficacy is often limited by tumor hypoxia and low radiosensitivity. Radiosensitizers that enhance RT without dose escalation are therefore of clinical interest. Alpha-mangostin (...

The γδ T cells belong to a subgroup of T cells known as non-conventional T cells due to their limited T cell receptor (TCR) repertoire and ability to recognize non-peptide antigens. They play a crucial role in combating infections and tum...

As a metabolism-controlling peptide, insulin affects activity of almost all tissues in human organisms, including the ones located in the central nervous system. By modifying glucose uptake and processing, as well as inducing anabolic effects, insuli...

Monkeypox (Mpox) has re-emerged as a global public health threat, with recent outbreaks linked to novel mutations that enhance viral transmissibility and immune evasion. The Mpox virus (MPXV), a double-stranded deoxyribonucleic acid (DNA) orthopoxvir...

Pharmaceutical care in European countries is at various stages of development. Although the problem of occupational burnout affects many professions, it is particularly relevant among healthcare workers, such as pharmacists. Studies assessing pharmac...

Changes in membrane lipid composition constitute a key bacterial resistance mechanism. In Staphylococcus aureus, phosphatidylglycerol undergoes lysine modification to form lysyl-phosphatidylglycerol, a cationic lipid that reduces the net negative sur...

Hydroethanolic Cucurbita pepo seed extracts are traditionally used for alleviating lower urinary tract symptoms (LUTS), yet their mechanisms remain unclear. Adenosine, a purine nucleoside involved in neuromodulation and smooth muscle relaxation, was...

This review explores the pharmacological potential of chondroitin sulfate and fucoidan as immunomodulatory agents targeting N-acetylgalactosaminidase (nagalase) to normalize immune responses. Nagalase, an enzyme produced by tumor and virus-infected c...