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Biology, Volume 13, Issue 1

January 2024 - 64 articles

Cover Story: Zebrafish larvae serve as an optimal model for investigating various ophthalmological and neurological conditions, with optokinetic reflex (OKR) assays proving invaluable. Despite the assay's growing popularity, a deficiency in clear reporting guidelines hinders the field. Enhanced reporting standards contribute to research reproducibility, diminish bias, and mitigate underreporting. This systematic literature review explores animal, environmental, and technical factors critical for the OKR assay in zebrafish. The analysis exposes inadequacies in past reporting, emphasizing the need for a systematic approach. To address this gap, we present the zebrafish optokinetic (ZOK) reflex minimal reporting guideline. This guideline aims to empower researchers to avoid future errors and foster more reliable and transparent research practices. View this paper
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Articles (64)

  • Article
  • Open Access
2 Citations
3,122 Views
13 Pages

Impacts, Potential Benefits and Eradication Feasibility of Aquatic Alien Species in an Integral Natural State Reserve

  • Daniele Paganelli,
  • Adriana Bellati,
  • Andrea Gazzola,
  • Francesco Bracco and
  • Daniele Pellitteri-Rosa

22 January 2024

Riverine wetlands are stepping-stone environments for the protection of local biodiversity, but they are particularly vulnerable to biological invasions. In order to take action against biological invasions, it is crucial to assess the impacts of ali...

  • Article
  • Open Access
5 Citations
3,420 Views
16 Pages

22 January 2024

Innate immune receptor TLR4 plays an important role in glycolipid metabolism. The objective of this study is to investigate the inhibitory effects of blocking TLR4 on hyperglycemia and hyperlipidemia by comparing WT and TLR4−/− mice in ob...

  • Article
  • Open Access
1 Citations
5,752 Views
12 Pages

Common Variants rs429358 and rs7412 in APOE Gene Are Not Associated with POAG in a Saudi Cohort

  • Altaf A. Kondkar,
  • Tahira Sultan,
  • Taif A. Azad,
  • Tanvir Khatlani,
  • Abdulaziz A. Alshehri,
  • Essam A. Osman,
  • Glenn P. Lobo,
  • Faisal A. Almobarak and
  • Saleh A. Al-Obeidan

22 January 2024

Adult-onset glaucoma, an age-related neurodegenerative disease, is very prevalent among the elderly Arabs of Saudi origin. This study investigated the association between apolipoprotein E (APOE) gene variants (rs429358 and rs7412) and primary open-an...

  • Review
  • Open Access
7 Citations
5,762 Views
14 Pages

The Role of NMNAT2/SARM1 in Neuropathy Development

  • Olga Tarasiuk,
  • Laura Molteni,
  • Alessio Malacrida and
  • Gabriella Nicolini

22 January 2024

Chemotherapy-induced peripheral neuropathy (CIPN) commonly arises as a side effect of diverse cancer chemotherapy treatments. This condition presents symptoms such as numbness, tingling, and altered sensation in patients, often accompanied by neuropa...

  • Article
  • Open Access
6 Citations
3,233 Views
21 Pages

20 January 2024

Four 1,10-phenanthroline derivatives (1–4) were synthesized as potential telomeric DNA binders, three substituted in their chains with thiosemicarbazones (TSCs) and one 4-phenylthiazole derivative. The compounds were characterized using NMR, HR...

  • Review
  • Open Access
19 Citations
5,862 Views
20 Pages

20 January 2024

The survival and spread of foodborne and nosocomial-associated bacteria through high-touch surfaces or contamination-prone sites, in either healthcare, domestic or food industry settings, are not always prevented by the employment of sanitary hygiene...

  • Article
  • Open Access
1 Citations
3,805 Views
25 Pages

Axonal Lysosomal Assays for Characterizing the Effects of LRRK2 G2019S

  • Priyanka Bhatia,
  • Marc Bickle,
  • Amay A. Agrawal,
  • Buster Truss,
  • Aikaterina Nikolaidi,
  • Kathrin Brockmann,
  • Lydia Reinhardt,
  • Stefanie Vogel,
  • Eva M. Szegoe and
  • Arun Pal
  • + 5 authors

20 January 2024

The degeneration of axon terminals before the soma, referred to as “dying back”, is a feature of Parkinson’s disease (PD). Axonal assays are needed to model early PD pathogenesis as well as identify protective therapeutics. We hypot...

  • Review
  • Open Access
3 Citations
3,276 Views
13 Pages

20 January 2024

Prion diseases are caused by the disease-specific self-templating infectious conformation of the host-encoded prion protein, PrPSc. Prion strains are operationally defined as a heritable phenotype of disease under controlled conditions. One of the ha...

  • Article
  • Open Access
7 Citations
3,457 Views
20 Pages

20 January 2024

The decline of Japanese eel (Anguilla japonica) populations in the Yangtze River estuary represents a critical conservation concern. Eleven-years of daily catch data during recruitment periods (i.e., January–April, 2012–2022) indicate tha...

  • Review
  • Open Access
8 Citations
11,274 Views
15 Pages

Looking Back, Going Forward: Understanding Cardiac Pathophysiology from Pressure–Volume Loops

  • Ilaria Protti,
  • Antoon van den Enden,
  • Nicolas M. Van Mieghem,
  • Christiaan L. Meuwese and
  • Paolo Meani

19 January 2024

Knowing cardiac physiology is essential for health care professionals working in the cardiovascular field. Pressure–volume loops (PVLs) offer a unique understanding of the myocardial working and have become pivotal in complex pathophysiological...

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Biology - ISSN 2079-7737