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Antibiotics, Volume 12, Issue 11

November 2023 - 86 articles

Cover Story: The antibiotic resistance of Porphyromonas gingivalis, a major pathogen in human periodontal disease, was studied over 20 years in the United States in severe periodontitis patients.  In 1999–2000, P. gingivalis resistance to clindamycin was rare, affecting only 0.6% of patients, but by 2019–2020 this resistance had risen to 9.3% (a 15-fold increase). Similarly, P. gingivalis resistance to amoxicillin increased from 0.1% of patients in 1999–2000 to 2.8% in 2019–2020 (a 28-fold increase). In comparison, negligible P. gingivalis resistance to metronidazole, metronidazole plus amoxicillin, and doxycycline over the 20-year study period was found. The increased antibiotic resistance of P. gingivalis and other periodontitis-associated bacteria threatens the efficacy of periodontal antimicrobial chemotherapy. View this paper
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Articles (86)

  • Article
  • Open Access
10 Citations
3,507 Views
16 Pages

Antibacterial Efficiency of Tanacetum vulgare Essential Oil against ESKAPE Pathogens and Synergisms with Antibiotics

  • Horațiu Roman,
  • Adelina-Gabriela Niculescu,
  • Veronica Lazăr and
  • Mihaela Magdalena Mitache

17 November 2023

Medicinal plants with multiple targets of action have become one of the most promising solutions in the fight against multidrug-resistant (MDR) bacterial infections. Tanacetum vulgare (Tansy) is one of the medicinal plants with antibacterial qualitie...

  • Systematic Review
  • Open Access
8 Citations
3,251 Views
19 Pages

Cemented versus Cementless Stem Fixation in Revision Total Knee Arthroplasty: A Systematic Review and Meta-Analysis

  • Ali Darwich,
  • Andrea Jovanovic,
  • Franz-Joseph Dally,
  • Asseel Abd El Hai,
  • Tobias Baumgärtner,
  • Elio Assaf,
  • Sascha Gravius,
  • Svetlana Hetjens and
  • Mohamad Bdeir

17 November 2023

The number of revision knee arthroplasties (rTKA) is growing significantly as is the use of intramedullary stems for optimized stability. The choice of the most appropriate stem fixation method is still controversial. The purpose of this meta-analysi...

  • Article
  • Open Access
13 Citations
3,360 Views
16 Pages

Antimicrobial Activity of Novel Ni(II) and Zn(II) Complexes with (E)-2-((5-Bromothiazol-2-yl)imino)methyl)phenol Ligand: Synthesis, Characterization and Molecular Docking Studies

  • Inas Al-Qadsy,
  • Waseem Sharaf Saeed,
  • Ahmad Abdulaziz Al-Owais,
  • Abdelhabib Semlali,
  • Ali Alrabie,
  • Lena Ahmed Saleh Al-Faqeeh,
  • Mohammed ALSaeedy,
  • Arwa Al-Adhreai,
  • Abdel-Basit Al-Odayni and
  • Mazahar Farooqui

17 November 2023

In order to address the challenges associated with antibiotic resistance by bacteria, two new complexes, Ni(II) and Zn(II), have been synthesized using the conventional method based on Schiff base ligand (E)-2-((5-bromothiazol-2-yl) imino) methyl) ph...

  • Editorial
  • Open Access
4 Citations
1,751 Views
3 Pages

17 November 2023

Antibiotic resistance (ABR) and antifungal resistance (AFR) arise when microorganisms evolve mechanisms to resist pharmacological treatments [...]

  • Article
  • Open Access
2,360 Views
13 Pages

17 November 2023

Decades of antimicrobial overuse to treat respiratory disease in foals have promoted the emergence and spread of zoonotic multidrug-resistant (MDR) Rhodococcus equi worldwide. Three main R. equi MDR clonal populations—2287, G2106, and G2017&mda...

  • Article
  • Open Access
10 Citations
3,053 Views
15 Pages

Effect of Hygiene Protocols on the Mechanical and Physical Properties of Two 3D-Printed Denture Resins Characterized by Extrinsic Pigmentation as Well as the Mixed Biofilm Formed on the Surface

  • Adriana Barbosa Ribeiro,
  • Beatriz Marcatto Tinelli,
  • Lorena Mosconi Clemente,
  • Beatriz de Camargo Poker,
  • Viviane de Cássia Oliveira,
  • Evandro Watanabe and
  • Cláudia Helena Silva-Lovato

17 November 2023

To assess the effect of hygiene protocols and time on the physical–mechanical properties and colony-forming units (CFU) of Candida albicans, Staphylococcus aureus, and Streptococcus mutans on 3D-printed denture resins (SmartPrint and Yller) wit...

  • Article
  • Open Access
3 Citations
2,210 Views
13 Pages

Racial Disparities in Periprosthetic Joint Infections after Primary Total Joint Arthroplasty: A Retrospective Study

  • Jodian A. Pinkney,
  • Joshua B. Davis,
  • Jamie E. Collins,
  • Fatma M. Shebl,
  • Matthew P. Jamison,
  • Jose I. Acosta Julbe,
  • Laura M. Bogart,
  • Bisola O. Ojikutu,
  • Antonia F. Chen and
  • Sandra B. Nelson

16 November 2023

In the United States, racial disparities have been observed in complications following total joint arthroplasty (TJA), including readmissions and mortality. It is unclear whether such disparities also exist for periprosthetic joint infection (PJI). T...

  • Article
  • Open Access
7 Citations
2,212 Views
10 Pages

15 November 2023

This study aimed to compare clinical characteristics and outcomes in patients with native joint septic arthritis (NJSA) due to methicillin-resistant Staphylococcus aureus (MRSA) in comparison to methicillin-sensitive S. aureus (MSSA) and identify tre...

  • Article
  • Open Access
4 Citations
2,139 Views
24 Pages

15 November 2023

This study was designed to evaluate the effects of different doses of the fibrous roots of Polygonatum cyrtonema Hua on the growth performance, slaughter parameters, meat quality, immune function, cytokines, antioxidant capacity, and intestinal morph...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,009 Views
11 Pages

Increase in Incidence Rates and Risk Factors for Multidrug Resistant Bacteria in Septic Children: A Nationwide Spanish Cohort Study (2013–2019)

  • María Slocker-Barrio,
  • Jesús López-Herce-Cid,
  • Amaya Bustinza-Arriortúa,
  • Elena Fresán-Ruiz,
  • Iolanda Jordán-García,
  • Juan Carlos de Carlos-Vicente,
  • Elvira Morteruel-Arizcuren,
  • Patricia García-Soler,
  • Montserrat Nieto-Moro and
  • Cristina Schüffelmann
  • + 6 authors

14 November 2023

The emergence of multidrug-resistant (MDR) bacteria in children is a growing concern, particularly among septic patients, given the need for first-right dosing. Our aim was to determine the incidence rates and factors associated with MDR-sepsis in th...

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Antibiotics - ISSN 2079-6382