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Biosensors, Volume 15, Issue 5

May 2025 - 69 articles

Cover Story: We present a graphene–quantum dot (QD) hybrid biosensor that achieves femtomolar sensitivity through a charge transfer-based quenching and recovery mechanism. Using single-layer graphene field-effect transistors (SLG-FETs) and time-resolved photoluminescence (TRPL), we demonstrate that photoluminescence quenching in QD–graphene hybrids results from static charge transfer rather than energy transfer. A simple analytical quantum mechanical model supports this interpretation. Electrical and optical signals show correlated responses to analyte concentration, enabling dual-mode detection. We validated the platform for biotin–streptavidin and IgG–anti-IgG interactions, achieving limits of detection down to 0.1 fM. These results establish a robust framework for next-generation, high-specificity biosensors. View this paper
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Articles (69)

  • Article
  • Open Access
1 Citations
1,016 Views
14 Pages

14 May 2025

Lateral flow immunoassay (LFIA) is a promising tool for rapid detection in the field of agricultural product analysis due to its advantages of cost-effectiveness and operational simplicity. In this work, Eu metal–organic frameworks (MOFs) were...

  • Review
  • Open Access
2 Citations
3,443 Views
22 Pages

Challenges in Adapting Fibre Optic Sensors for Biomedical Applications

  • Sahar Karimian,
  • Muhammad Mahmood Ali,
  • Marion McAfee,
  • Waqas Saleem,
  • Dineshbabu Duraibabu,
  • Sanober Farheen Memon and
  • Elfed Lewis

13 May 2025

Fibre optic sensors (FOSs) have developed as a transformative technology in healthcare, often offering unparalleled accuracy and sensitivity in monitoring various physiological and biochemical parameters. Their applications range from tracking vital...

  • Communication
  • Open Access
1,469 Views
10 Pages

Wearable Humidity Sensor Using Cs3Cu2I5 Metal Halides with Hydroxyl Selective Phase Transition for Breath Monitoring

  • Si Hyeok Yang,
  • Lim Kyung Oh,
  • Dong Ho Lee,
  • Donghoon Gwak,
  • Nara Song,
  • Bowon Oh,
  • Na Young Lee,
  • Hongki Kim,
  • Han Seul Kim and
  • Jin Woo Choi

13 May 2025

The low-dimensional metal halide Cs3Cu2I5 exhibits unique electrical and chemical properties. Notably, it undergoes a phase transition to CsCu2I3 upon exposure to hydroxyl (-OH) gas, resulting in significant changes in its electrical characteristics....

  • Article
  • Open Access
1,794 Views
13 Pages

Individually Modified Microneedle Array for Minimal Invasive Multi-Electrolyte Monitoring

  • Ketian Yu,
  • Yukun Ma,
  • Yiming Wei,
  • Wanying Chen,
  • Zhen Dai,
  • Yu Cai,
  • Xuesong Ye and
  • Bo Liang

12 May 2025

Electrolytes play crucial roles in regulating nerve and muscle functions. Currently, microneedle technology enables real-time electrolyte monitoring through minimally invasive methods. However, due to the small size of microneedles, performing multi-...

  • Article
  • Open Access
2 Citations
1,930 Views
14 Pages

12 May 2025

Genetic mutation detection for colorectal cancer (CRC) is crucial for precision diagnosis and treatment, yet current methods often suffer from challenges such as low sensitivity, time consumption, and high costs. In our preliminary bioinformatic anal...

  • Review
  • Open Access
9 Citations
8,202 Views
45 Pages

12 May 2025

This review highlights the latest developments in wearable electrochemical glucose sensors, focusing on their transition from invasive to non-invasive and minimally invasive designs. We discuss the underlying mechanisms, performance metrics, and prac...

  • Article
  • Open Access
1,594 Views
14 Pages

A Microfluidic Device Integrating a Glucose Sensor and Calibration Function for Cell-Based Assays

  • Laner Chen,
  • Kenta Shinha,
  • Hiroko Nakamura,
  • Kikuo Komori and
  • Hiroshi Kimura

11 May 2025

Microphysiological systems (MPS) incorporating microfluidic technologies offer improved physiological relevance and real-time analysis for cell-based assays, but often lack non-invasive monitoring capabilities. Addressing this gap, we developed a mic...

  • Article
  • Open Access
1 Citations
1,563 Views
19 Pages

11 May 2025

Urinary incontinence affects many women, yet there are no monitoring devices capable of accurately capturing flow dynamics during everyday activities. Building on our initial development of a wearable personal uroflowmeter, this study enhances the de...

  • Article
  • Open Access
1,120 Views
21 Pages

Gait Phase Recognition in Multi-Task Scenarios Based on sEMG Signals

  • Xin Shi,
  • Xiaheng Zhang,
  • Pengjie Qin,
  • Liangwen Huang,
  • Yaqin Zhu and
  • Zixiang Yang

10 May 2025

In the human–exoskeleton interaction process, accurately recognizing gait phases is crucial for effectively assessing the assistance provided by the exoskeleton. However, due to the similarity in muscle activation patterns between adjacent gait...

  • Article
  • Open Access
1,055 Views
16 Pages

Multi-Parametric Electrochemical Sensing Platform: Applications in Animal Welfare

  • C. Ferreira,
  • E. Lynch,
  • A. O’Herlihy,
  • F. Barry,
  • L. C. Nagle,
  • S. R. Teixeira and
  • P. Galvin

10 May 2025

The rapid growth of the dairy sector requires advanced monitoring tools to ensure sustainable practices that benefit the environment, economy, and human health. Current monitoring devices often lack multi-parametric capabilities, limiting their abili...

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Biosensors - ISSN 2079-6374