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Biosensors, Volume 13, Issue 5

May 2023 - 76 articles

Cover Story: State of the art clinical detection methods typically involve immunoassays that require specialized equipment and trained personnel. This impedes their use in point-of-care (PoC), where ease of operation, portability, and cost efficiency are prioritized. Small electrochemical biosensors are considered a way to facilitate this translation. In this paper, different electrochemical approaches using off-shelf components were evaluated, where chronoamperometry gave the best performance. This approach was demonstrated by measuring multiple biomarkers in bodily fluids and represents a general platform for the application of immunoassays to small electrochemical biosensors. Coupling this platform with miniature potentiostats would create a simple and compact device, fit for a PoC environment. View this paper
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Articles (76)

  • Article
  • Open Access
17 Citations
5,023 Views
13 Pages
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On-Field Test of Tuberculosis Diagnosis through Exhaled Breath Analysis with a Gas Sensor Array

  • Yolande Christelle Ketchanji Mougang,
  • Laurent-Mireille Endale Mangamba,
  • Rosamaria Capuano,
  • Fausto Ciccacci,
  • Alexandro Catini,
  • Roberto Paolesse,
  • Hugo Bertrand Mbatchou Ngahane,
  • Leonardo Palombi and
  • Corrado Di Natale
Biosensors2023, 13(5), 570;https://doi.org/10.3390/bios13050570

22 May 2023

Tuberculosis (TB) is among the more frequent causes of death in many countries. For pulmonary TB, early diagnosis greatly increases the efficiency of therapies. Although highly sensitive tests based on nucleic acid amplification tests (NAATs) and loo...

Full Article
  • Review
  • Open Access
39 Citations
7,949 Views
34 Pages
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Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods

  • Yusuf Aslan,
  • Maryam Atabay,
  • Hussain Kawsar Chowdhury,
  • Ilgım Göktürk,
  • Yeşeren Saylan and
  • Fatih Inci
Biosensors2023, 13(5), 569;https://doi.org/10.3390/bios13050569

22 May 2023

Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical road for the improved application of biomedicine through the deployment of accurate and affordable programs into resource-scarce settings. The utilization of anti...

Full Article
  • Review
  • Open Access
62 Citations
9,930 Views
33 Pages
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A Review on Photonic Sensing Technologies: Status and Outlook

  • Muhammad A. Butt,
  • Nikolay L. Kazanskiy,
  • Svetlana N. Khonina,
  • Grigory S. Voronkov,
  • Elizaveta P. Grakhova and
  • Ruslan V. Kutluyarov
Biosensors2023, 13(5), 568;https://doi.org/10.3390/bios13050568

22 May 2023

In contemporary science and technology, photonic sensors are essential. They may be made to be extremely resistant to some physical parameters while also being extremely sensitive to other physical variables. Most photonic sensors may be incorporated...

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  • Article
  • Open Access
8 Citations
2,920 Views
13 Pages
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Fe3O4@Au Core–Shell Magnetic Nanoparticles for the Rapid Analysis of E. coli O157:H7 in an Electrochemical Immunoassay

  • Shayesteh Bazsefidpar,
  • Maria Freitas,
  • Clara R. Pereira,
  • Gemma Gutiérrez,
  • Esther Serrano-Pertierra,
  • Henri P. A. Nouws,
  • María Matos,
  • Cristina Delerue-Matos and
  • María Carmen Blanco-López
Biosensors2023, 13(5), 567;https://doi.org/10.3390/bios13050567

22 May 2023

Escherichia coli (E. coli) O157:H7 is a pathogenic bacterium that causes serious toxic effects in the human gastrointestinal tract. In this paper, a method for its effective analytical control in a milk sample was developed. To perform rapid (1 h) an...

Full Article
  • Article
  • Open Access
8 Citations
4,640 Views
15 Pages
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Direct Electron Transfer of Glucose Oxidase on Pre-Anodized Paper/Carbon Electrodes Modified through Zero-Length Cross-Linkers for Glucose Biosensors

  • Gilberto Henao-Pabon,
  • Ning Gao,
  • K. Sudhakara Prasad and
  • XiuJun Li
Biosensors2023, 13(5), 566;https://doi.org/10.3390/bios13050566

22 May 2023

A disposable paper-based glucose biosensor with direct electron transfer (DET) of glucose oxidase (GOX) was developed through simple covalent immobilization of GOX on a carbon electrode surface using zero-length cross-linkers. This glucose biosensor...

Full Article
  • Communication
  • Open Access
8 Citations
2,681 Views
9 Pages
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Highly Sensitive Detection of Urea Using Si Electrolyte-Gated Transistor with Low Power Consumption

  • Wonyeong Choi,
  • Bo Jin,
  • Seonghwan Shin,
  • Jeonghyeon Do,
  • Jongmin Son,
  • Kihyun Kim and
  • Jeong-Soo Lee
Biosensors2023, 13(5), 565;https://doi.org/10.3390/bios13050565

22 May 2023

We experimentally demonstrate Si-based electrolyte-gated transistors (EGTs) for detecting urea. The top-down-fabricated device exhibited excellent intrinsic characteristics, including a low subthreshold swing (SS) (~80 mV/dec) and a high on/off curre...

Full Article
  • Article
  • Open Access
6 Citations
2,848 Views
14 Pages
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Selection of a Novel DNA Aptamer Specific for 5-Hydroxymethylfurfural Using Capture-SELEX

  • Xixia Liu,
  • Yingyu Hou,
  • Yanlin Qin,
  • Jiaxin Cheng,
  • Jianjun Hou,
  • Qin Wu and
  • Zhenmin Liu
Biosensors2023, 13(5), 564;https://doi.org/10.3390/bios13050564

22 May 2023

A capture systematic evolution of ligands by exponential enrichment (Capture-SELEX) was described to discover novel aptamers specific for 5-hydroxymethylfurfural (5-HMF), and a biosensor based on molecular beacon was constructed to detect 5-HMF. The...

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  • Article
  • Open Access
14 Citations
4,408 Views
14 Pages
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Electrodeposited rGO/AuNP/MnO2 Nanocomposite-Modified Screen-Printed Carbon Electrode for Sensitive Electrochemical Sensing of Arsenic(III) in Water

  • Yanqing Wu,
  • Tao Zhang,
  • Lishen Su and
  • Xiaoping Wu
Biosensors2023, 13(5), 563;https://doi.org/10.3390/bios13050563

21 May 2023

Herein, a simple and portable electrochemical sensor based on a reduced graphene oxide/gold nanoparticle/manganese dioxide (rGO/AuNP/MnO2) nanocomposite-modified screen-printed carbon electrode (SPCE) was constructed by the facile stepwise electrodep...

Full Article
  • Article
  • Open Access
16 Citations
3,151 Views
15 Pages
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Electrochemical Biosensing of L-DOPA Using Tyrosinase Immobilized on Carboxymethyl Starch-Graft-Polyaniline@MWCNTs Nanocomposite

  • Fahimeh Mollamohammadi,
  • Hassan Faridnouri and
  • Ehsan Nazarzadeh Zare
Biosensors2023, 13(5), 562;https://doi.org/10.3390/bios13050562

21 May 2023

The electrochemical behavior of the immobilized tyrosinase (Tyrase) on a modified glassy carbon electrode with carboxymethyl starch-graft-polyaniline/multi-walled carbon nanotubes nanocomposite (CMS-g-PANI@MWCNTs) was investigated. The molecular prop...

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  • Article
  • Open Access
1 Citations
2,620 Views
16 Pages
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Development of an Efficient FRET-Based Ratiometric Uranium Biosensor

  • Sandrine Sauge-Merle,
  • Morgane Recuerda,
  • Maria Rosa Beccia,
  • David Lemaire,
  • Rym Cherif,
  • Nicolas Bremond,
  • Fabienne Merola,
  • Yasmina Bousmah and
  • Catherine Berthomieu
Biosensors2023, 13(5), 561;https://doi.org/10.3390/bios13050561

19 May 2023

The dispersion of uranium in the environment can pose a problem for the health of humans and other living organisms. It is therefore important to monitor the bioavailable and hence toxic fraction of uranium in the environment, but no efficient measur...

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