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Biosensors, Volume 13, Issue 6

June 2023 - 98 articles

Cover Story: Maximal safe resection of glioblastoma (GBM) remains a challenge due to its invasive capacity. In order to provide innovative approaches to this clinical problem, we have used a nanostructured gold biosensor that we previously developed to discriminate cancer from normal cells. We conducted a prospective study with 35 paired surgical samples, tumor and peritumoral tissue, from GBM patients undergoing surgical treatment. Tissue imprints were left on the biosensor and analyzed to obtain the difference in the refractive index (RI) at each position in the biosensor between both tissues in each case. The RI values were significantly higher (p = 0.0047) in the tumor compared with the peritumoral samples. We also propose a biosensor setup for the operating room that would enable real-time discrimination between tumor and peritumoral tissues. View this paper
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Articles (98)

  • Article
  • Open Access
5 Citations
1,770 Views
15 Pages

Predictive Cell Culture Time Evolution Based on Electric Models

  • Juan Alfonso Serrano,
  • Pablo Pérez,
  • Paula Daza,
  • Gloria Huertas and
  • Alberto Yúfera

20 June 2023

Obtaining cell concentration measurements from a culture assay by using bioimpedance is a very useful method that can be used to translate impedances to cell concentration values. The purpose of this study was to find a method to obtain the cell conc...

  • Article
  • Open Access
7 Citations
3,122 Views
13 Pages

Development and In-House Validation of an Enzyme-Linked Immunosorbent Assay and a Lateral Flow Immunoassay for the Dosage of Tenofovir in Human Saliva

  • Simone Cavalera,
  • Thea Serra,
  • Antonio Abad-Fuentes,
  • Josep V. Mercader,
  • Antonio Abad-Somovilla,
  • Fabio Di Nardo,
  • Antonio D’Avolio,
  • Amedeo De Nicolò,
  • Valentina Testa and
  • Matteo Chiarello
  • + 2 authors

20 June 2023

Highly active antiretroviral therapy (HAART) includes very potent drugs that are often characterized by high toxicity. Tenofovir (TFV) is a widely used drug prescribed mainly for pre-exposure prophylaxis (PreP) and the treatment of human immunodefici...

  • Review
  • Open Access
17 Citations
4,971 Views
36 Pages

19 June 2023

Recently, there has been an upsurge in the extent to which electrochemiluminescence (ECL) working in synergy with bipolar electrochemistry (BPE) is being applied in simple biosensing devices, especially in a clinical setup. The key objective of this...

  • Article
  • Open Access
3 Citations
2,761 Views
14 Pages

19 June 2023

The development of multifunctional biomimetic nanozymes with high catalytic activity and sensitive response is rapidly advancing. The hollow nanostructures, including metal hydroxides, metal-organic frameworks, and metallic oxides, possess excellent...

  • Article
  • Open Access
11 Citations
2,889 Views
12 Pages

BPA Endocrine Disruptor Detection at the Cutting Edge: FPIA and ELISA Immunoassays

  • Anna Raysyan,
  • Sandro D. Zwigart,
  • Sergei A. Eremin and
  • Rudolf J. Schneider

19 June 2023

BPA is a chemical commonly used in the production of polymer-based materials that can have detrimental effects on the thyroid gland and impact human reproductive health. Various expensive methods, such as liquid and gas chromatography, have been sugg...

  • Review
  • Open Access
20 Citations
6,721 Views
22 Pages

Current Innovations in Intraocular Pressure Monitoring Biosensors for Diagnosis and Treatment of Glaucoma—Novel Strategies and Future Perspectives

  • Rubiya Raveendran,
  • Lokesh Prabakaran,
  • Rethinam Senthil,
  • Beryl Vedha Yesudhason,
  • Sankari Dharmalingam,
  • Weslen Vedakumari Sathyaraj and
  • Raji Atchudan

18 June 2023

Biosensors are devices that quantify biologically significant information required for diverse applications, such as disease diagnosis, food safety, drug discovery and detection of environmental pollutants. Recent advancements in microfluidics, nanot...

  • Article
  • Open Access
12 Citations
3,781 Views
12 Pages

A Ratiometric Fluorescent Probe for Hypochlorite and Lipid Droplets to Monitor Oxidative Stress

  • Mousumi Baruah,
  • Anal Jana,
  • Niharika Pareek,
  • Shikha Singh and
  • Animesh Samanta

17 June 2023

Mitochondria are valuable subcellular organelles and play crucial roles in redox signaling in living cells. Substantial evidence proved that mitochondria are one of the critical sources of reactive oxygen species (ROS), and overproduction of ROS acco...

  • Article
  • Open Access
24 Citations
3,098 Views
14 Pages

16 June 2023

Herein we report a highly specific electrochemical aptasenseor for AFB1 determination based on AFB1-controlled diffusion of redox probe (Ru(NH3)63+) through nanochannels of AFB1-specific aptamer functionalized VMSF. A high density of silanol groups o...

  • Article
  • Open Access
6 Citations
2,995 Views
14 Pages

16 June 2023

Aptamers are an excellent choice for the selective detection of small molecules. However, the previously reported aptamer for chloramphenicol suffers from low affinity, probably as a result of steric hindrance due to its bulky nature (80 nucleotides)...

  • Article
  • Open Access
23 Citations
4,866 Views
12 Pages

Ultrasensitive and Rapid Visual Detection of Escherichia coli O157:H7 Based on RAA-CRISPR/Cas12a System

  • Lishan Zhu,
  • Zhenda Liang,
  • Yongtao Xu,
  • Zhiquan Chen,
  • Jiasi Wang and
  • Li Zhou

16 June 2023

Escherichia coli (E. coli) O157:H7 is a major foodborne and waterborne pathogen that can threaten human health. Due to its high toxicity at low concentrations, it is crucial to establish a time-saving and highly sensitive in situ detection method. He...

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Biosensors - ISSN 2079-6374Creative Common CC BY license