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Biosensors, Volume 11, Issue 2

February 2021 - 32 articles

Cover Story: The measurement of the chemical parameters of binding between cell adhesion molecules and extracellu-lar ligands using live-cell assays is a challenging task. Here, for the first time, we used a computer-controlled micropipette to measure cell adhesion on PLL-g-PEG-based surface coatings with various ligand densities to determine the dissociation constant of the integrin–RGD bond. We use a simple biophysical model to fit the weighted average of adhesion histograms. The results are confirmed by applying a resonant waveguide-based biosensor. Furthermore, we present a subpopulation analysis of the data emphasizing the single-cell capabili-ties of the method. We find that most cells are found in the weak adhesion range, while a growing, strongly adhered subpopulation appears with the increase of RGD surface density. View this paper.
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Articles (32)

  • Review
  • Open Access
51 Citations
7,941 Views
32 Pages

Fiber Optic Sensors for Vital Signs Monitoring. A Review of Its Practicality in the Health Field

  • Christian Perezcampos Mayoral,
  • Jaime Gutiérrez Gutiérrez,
  • José Luis Cano Pérez,
  • Marciano Vargas Treviño,
  • Itandehui Belem Gallegos Velasco,
  • Pedro António Hernández Cruz,
  • Rafael Torres Rosas,
  • Lorenzo Tepech Carrillo,
  • Judith Arnaud Ríos and
  • Edmundo López Apreza
  • + 1 author

23 February 2021

Vital signs not only reflect essential functions of the human body but also symptoms of a more serious problem within the anatomy; they are well used for physical monitoring, caloric expenditure, and performance before a possible symptom of a massive...

  • Article
  • Open Access
5 Citations
2,699 Views
11 Pages

21 February 2021

Microbial reactor sensors (based on freshly harvested intact microbial cells) or microbial membrane sensors (based on immobilized microbial cells) can be used as convenient instruments for studying processes that cause the response of a biosensor, su...

  • Article
  • Open Access
13 Citations
4,543 Views
20 Pages

Electrical Characterization of Cellulose-Based Membranes towards Pathogen Detection in Water

  • Grégoire Le Brun,
  • Margo Hauwaert,
  • Audrey Leprince,
  • Karine Glinel,
  • Jacques Mahillon and
  • Jean-Pierre Raskin

21 February 2021

Paper substrates are promising for development of cost-effective and efficient point-of-care biosensors, essential for public healthcare and environmental diagnostics in emergency situations. Most paper-based biosensors rely on the natural capillarit...

  • Review
  • Open Access
84 Citations
9,189 Views
24 Pages

Recent Advances in Nanotechnology-Based Diagnosis and Treatments of Human Osteosarcoma

  • Mahmood Barani,
  • Mahwash Mukhtar,
  • Abbas Rahdar,
  • Saman Sargazi,
  • Sadanand Pandey and
  • Misook Kang

20 February 2021

Osteosarcoma (OSA) is a type of bone cancer that begins in the cells that form bones. OSA is a rare mesenchymal bone neoplasm derived from mesenchymal stem cells. Genome disorganization, chromosomal modifications, deregulation of tumor suppressor gen...

  • Article
  • Open Access
13 Citations
3,024 Views
11 Pages

19 February 2021

This research reports a portable immunochip, based on quartz crystal microbalance (QCM) for label-free, low-cost qualitative detection of zearalenone (ZEN) in food samples. The experimental parameters in the functionalization and working process were...

  • Article
  • Open Access
10 Citations
4,401 Views
11 Pages

19 February 2021

In this report, we summarized our development of biosensors for Rhodamine 6G and in vitro glucose detection based on surface-enhanced Raman scattering technology. For the detection of both Rhodamine 6G and in vitro glucose, a nature-patterned substra...

  • Article
  • Open Access
7 Citations
2,990 Views
13 Pages

A Useful Combination of Quantitative Ultrashort Echo Time MR Imaging and a Probing Device for Biomechanical Evaluation of Articular Cartilage

  • Takehito Hananouchi,
  • Yanjun Chen,
  • Saeed Jerban,
  • Masaru Teramoto,
  • Yajun Ma,
  • Erik W. Dorthe,
  • Eric Y. Chang,
  • Jiang Du and
  • Darryl D. D’Lima

17 February 2021

In this study, we combined quantitative ultrashort echo time (UTE) magnetic resonance (MR) imaging and an investigation by a probing device with tri-axial force sensor to seek correlations with mechanical properties of human patellar cartilage for in...

  • Article
  • Open Access
23 Citations
4,364 Views
18 Pages

Dielectrophoretic Characterization of Tenogenically Differentiating Mesenchymal Stem Cells

  • Anthony T. Giduthuri,
  • Sophia K. Theodossiou,
  • Nathan R. Schiele and
  • Soumya K. Srivastava

16 February 2021

Tendons are collagenous musculoskeletal tissues that connect muscles to bones and transfer the forces necessary for movement. Tendons are susceptible to injury and heal poorly, with long-term loss of function. Mesenchymal stem cell (MSC)-based therap...

  • Review
  • Open Access
92 Citations
13,001 Views
23 Pages

16 February 2021

Screen-printed technology has helped considerably to the development of portable electrochemical sensors since it provides miniaturized but robust and user-friendly electrodes. Moreover, this technology allows to obtain very versatile transducers, no...

  • Communication
  • Open Access
41 Citations
8,918 Views
12 Pages

14 February 2021

This paper presents a lateral flow assay (LFA) for the quantitative, fluorescence-based detection of the cardiac biomarker troponin I (cTnI) that features an analytical strip made of cellulose filter paper. The results show that the wicking and test...

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Biosensors - ISSN 2079-6374