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Journal of Functional Biomaterials, Volume 9, Issue 1

March 2018 - 25 articles

Cover Story: Beyond being the repository of genetic information, DNA is playing an increasingly important role as a building block for molecular electronics. Its inherent structural and molecular recognition properties render it a leading candidate for molecular electronics applications. The structural stability, diversity, and programmability of DNA provide overwhelming freedom for the design and fabrication of molecular-scale devices. In the past two decades, DNA has therefore attracted enormous attention in the field of molecular electronics. This review gives a brief survey of the recent experimental progress in DNA-based single-molecule electronics with special focus on single-molecule conductance and I–V characteristics of individual DNA molecules. View this paper.
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Articles (25)

  • Feature Paper
  • Article
  • Open Access
15 Citations
8,696 Views
17 Pages

The aim of this study is to assess the additive manufacture of morphometric models of healthy and diseased coronary arteries. Using a dissected porcine coronary artery, a model was developed with the use of computer aided engineering, with splines us...

  • Review
  • Open Access
51 Citations
11,728 Views
24 Pages

Advances in Degradable Embolic Microspheres: A State of the Art Review

  • Jensen Doucet,
  • Lauren Kiri,
  • Kathleen O’Connell,
  • Sharon Kehoe,
  • Robert J. Lewandowski,
  • David M. Liu,
  • Robert J. Abraham and
  • Daniel Boyd

Considerable efforts have been placed on the development of degradable microspheres for use in transarterial embolization indications. Using the guidance of the U.S. Food and Drug Administration (FDA) special controls document for the preclinical eva...

  • Feature Paper
  • Review
  • Open Access
262 Citations
21,864 Views
20 Pages

Hydrogels for Hydrophobic Drug Delivery. Classification, Synthesis and Applications

  • Eneko Larrañeta,
  • Sarah Stewart,
  • Michael Ervine,
  • Rehan Al-Kasasbeh and
  • Ryan F. Donnelly

Hydrogels have been shown to be very useful in the field of drug delivery due to their high biocompatibility and ability to sustain delivery. Therefore, the tuning of their properties should be the focus of study to optimise their potential. Hydrogel...

  • Article
  • Open Access
21 Citations
16,160 Views
9 Pages

Route and Type of Formulation Administered Influences the Absorption and Disposition of Vitamin B12 Levels in Serum

  • Luis Vitetta,
  • Joyce Zhou,
  • Rachel Manuel,
  • Serena Dal Forno,
  • Sean Hall and
  • David Rutolo

The administration of biological compounds that optimize health benefits is an ever-evolving therapeutic goal. Pharmaceutical and other adjunctive biological compounds have been administered via many different routes in order to produce a systemic ph...

  • Article
  • Open Access
6 Citations
7,207 Views
8 Pages

Trapezium Bone Density—A Comparison of Measurements by DXA and CT

  • Sebastian Breddam Mosegaard,
  • Kamille Breddam Mosegaard,
  • Nadia Bouteldja,
  • Torben Bæk Hansen and
  • Maiken Stilling

Bone density may influence the primary fixation of cementless implants, and poor bone density may increase the risk of implant failure. Before deciding on using total joint replacement as treatment in osteoarthritis of the trapeziometacarpal joint, i...

  • Feature Paper
  • Review
  • Open Access
501 Citations
31,680 Views
24 Pages

Formulation of Poloxamers for Drug Delivery

  • Andrew M. Bodratti and
  • Paschalis Alexandridis

Poloxamers, also known as Pluronics®, are block copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), which have an amphiphilic character and useful association and adsorption properties emanating from this. Poloxamers find use in...

  • Feature Paper
  • Review
  • Open Access
218 Citations
23,284 Views
20 Pages

Platelet Rich Plasma: New Insights for Cutaneous Wound Healing Management

  • Deborah Chicharro-Alcántara,
  • Mónica Rubio-Zaragoza,
  • Elena Damiá-Giménez,
  • José M. Carrillo-Poveda,
  • Belén Cuervo-Serrato,
  • Pau Peláez-Gorrea and
  • Joaquín J. Sopena-Juncosa

The overall increase of chronic degenerative diseases associated with ageing makes wound care a tremendous socioeconomic burden. Thus, there is a growing need to develop novel wound healing therapies to improve cutaneous wound healing. The use of reg...

  • Feature Paper
  • Review
  • Open Access
56 Citations
16,621 Views
31 Pages

Beyond being the repository of genetic information, DNA is playing an increasingly important role as a building block for molecular electronics. Its inherent structural and molecular recognition properties render it a leading candidate for molecular...

  • Feature Paper
  • Review
  • Open Access
102 Citations
21,088 Views
8 Pages

Nowadays, dental implants have become more common treatment for replacing missing teeth and aim to improve chewing efficiency, physical health, and esthetics. The favorable clinical performance of dental implants has been attributed to their firm oss...

  • Feature Paper
  • Review
  • Open Access
67 Citations
15,836 Views
18 Pages

Bisphosphonates (BPs) are the most utilized drugs for the treatment of osteoporosis, and are usefully employed also for other pathologies characterized by abnormally high bone resorption, including bone metastases. Due to the great affinity of these...

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J. Funct. Biomater. - ISSN 2079-4983