2025 August - 36 articles
Ultrasound-responsive nanomaterials represent a promising approach for achieving non-invasive and localized drug delivery within tumor microenvironments. In this study, we developed a piezocatalysis-assisted hydrogel system that integrates reactive o...
Magnesium (Mg) alloys, particularly Mg AZ31, have emerged as promising biomaterials for orthopedic applications due to their biodegradability and favorable mechanical characteristics. Among these, the Mg AZ31+SPF alloy, subjected to hydrothermal (HT)...
Background: A trilayered collagen/collagen–magnesium–hydroxyapatite (Col/Col-Mg-HA) scaffold is used in clinical practice to treat osteochondral lesions, but the regeneration of the subchondral bone is still not satisfactory. Objective: T...
Background: A major challenge in adhesive dentistry, often leading to restoration failure, is microleakage. This in vitro comparative study was designed to assess microleakage at the tooth–composite interface. The investigation aimed to compare...
Composite scaffolds based on a hydrogel matrix modified with hydroxyapatite, magnesium, or zinc compounds are promising for filling and regenerating osteochondral defects due to the specific biological properties of these modifiers. The aim of this w...
In pediatric endodontic procedures, final crown placement is often delayed, requiring the use of temporary filling materials to seal the access cavity. Given the importance of antibacterial properties in temporary restorations and the known antimicro...
Regenerative dentistry hopes to restore oral health by replacing diseased or damaged tissues with biologically functional, integrated counterparts [...]
Background: Common bile duct (CBD) treatments are often associated with complications, limiting long-term efficacy. To overcome these issues, polymeric grafts have been suggested as promising alternatives, since they are highly customizable, biocompa...
Background: Primary implant stability is a critical factor for successful osseointegration and long-term implant success. This study investigates the impact of drilling protocol modifications on primary stability, considering different bone qualities...
The development of efficient antibiotic-releasing materials derived from sustainable and recyclable compounds represents a key area within biomedical materials science, particularly in the treatment of antibacterial infections. Herein, a Fe3+/terepht...
In this study, a shape-changeable 3D scaffold with photothermal effects was developed to address the clinical challenges of complex bone defects. The multifunctional construct was fabricated via in situ polymerization combined with a gas foaming tech...
The success rate of root canal treatment is high, but it can fail. In these cases, orthograde root canal retreatment is often the treatment of choice, for which numerous biomaterials are available on the market, including endodontic files. This syste...
This study aimed to develop and evaluate a bakuchiol-loaded thermosensitive hydrogel (BTH) as a novel local drug delivery system for the management of periodontitis. Bakuchiol, a natural phenolic compound extracted from Psoralea corylifolia, was inco...
Orthodontic mini-implants are well-known anchorage devices and stand out as a particularly effective tool for ensuring maximum anchorage without relying on patient compliance. Therefore, it is necessary to understand what levels of torque strains rem...
The mechanical behavior of dental composites depends on the sample size and stress configuration. This makes it difficult to extrapolate laboratory data to clinical restorations with significant variations in size and geometry. Intrinsic parameters,...
This study assessed and compared the shear bond strength of self-adhesive and self-etching resin cements for indirect aesthetic restorations to dentin. Four different materials, lithium disilicate ceramics, zirconia ceramics, polymethyl methacrylate...
Zirconia is used widely for high-precision custom abutments; however, stress concentration can compromise osseointegration. Although glass–ceramic spray deposition (GCSD) can enhance the surface properties of zirconia, its biological effects re...
Pressure therapy combined with silicone has a significant effect on scar hyperplasia, but limitations such as long-term wearing of compression garments (CGs) can easily cause bacterial infection, cleanliness, and lifespan problems of CGs caused by th...
This study aimed to compare the performance of three hydroxyapatite–β-tricalcium phosphate (HA–β-TCP) collagen composite grafts in a canine model for extraction socket preservation. Eight mongrel dogs underwent atraumatic bilate...
Poly(organo)phosphazenes (PPZs) are increasingly recognized as versatile biomaterials for drug delivery applications in nanomedicine. Their unique hybrid structure—featuring an inorganic backbone and highly tunable organic side chains—con...
The aim of this study was to evaluate the impact of autoclaving on the dimensional stability of surgical guides (SGs) for aesthetic crown lengthening (ACL) using different resins/printing methods. Fifty SGs for ACL were printed using five different r...
The thermo-chemical treatment of dental implants leads to the formation of sodium titanate crystals on their surface. When in contact with blood, these crystals dissolve and trigger an ionic exchange cascade, resulting in the formation of a calcium a...
The main objective of this study was to compare the long-term outcomes of transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis, focusing on differences between self-expanding valve (SEV) versus balloon-expandable val...
Background: The role of collagen membrane fixation during guided bone regeneration (GBR) remains debatable, particularly in post-extraction sockets with buccal defects and concomitant immediate implant placement. This study evaluated whether or not f...
Laser powder bed fusion (LPBF) is an advanced additive manufacturing technology that is gaining increasing interest for biomedical implants because it can produce dense, patient-specific metallic components with controlled microstructures. This study...
Scaffolds are widely used in bioengineering, both as 3D native tissue-mimicking models for investigating mechanisms under physiological and pathological conditions and also as implantable agents in regenerative medicine. Histological approaches, main...
Three-dimensional printing is commonly used to fabricate provisional dental restorations. Studies have reported that changes in printing orientation affect the physical and mechanical properties of 3D-printed polymeric provisional restorations; howev...
The dimensional accuracy of the intaglio surface of complete dentures fabricated using liquid crystal display (LCD) three-dimensional (3D) printing might be influenced by the build angle and post-processing storage conditions. This study evaluated th...
Atomic force microscopy (AFM)-based nanoindentation enables investigation of the mechanical response of biological materials at a subcellular scale. However, quantitative estimates of mechanical parameters such as the elastic modulus (E) remain unrel...
Bioactive glass materials have been used for decades in orthopedic surgery, traumatology, and oral and maxillofacial surgery to repair bone defects. This study aimed to evaluate in vitro the survival and proliferation of MG63 human osteosarcoma-deriv...
Cell migration assays provide valuable insights into pathological conditions, such as tumor metastasis and immune cell infiltration, and the regenerative capacity of tissues. In vitro tools commonly used for cell migration studies exploit commercial...
This study evaluated the bone regeneration effect and mechanical properties of “Sticky bone”, a mixture of platelet-rich fibrin (PRF) and synthetic bone grafts (SBGs), in the repair of large femoral bone defects in rabbits. Eighteen New Z...
Amorphous calcium phosphate (ACP) is a well-established bioceramic material known to promote the remineralization of dental hard tissues. White spot lesions (WSLs) represent the initial stage of enamel demineralization and are frequently observed in...
Three-dimensional cell culture systems are relevant in vitro models for studying cellular behavior. In this regard, this present study investigates the interaction between human osteoblast-like cells and 3D-printed scaffolds mimicking physiological a...
Periodontitis is a chronic, multifactorial inflammatory disease characterized by the progressive destruction of the periodontal supporting tissues, including alveolar bone, potentially resulting in tooth loss. Etiopathogenesis involves a dysbiotic sh...
In this study, 3D Mg scaffolds were obtained by the spark plasma sintering (SPS), and a calcium phosphate coating was then obtained on the samples by the plasma electrolytic oxidation. A hybrid coating with vancomycin, zoledronic acid, and menaquinon...
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