You are currently viewing a new version of our website. To view the old version click .

Journal of Functional Biomaterials, Volume 16, Issue 6

June 2025 - 38 articles

Cover Story: Superparamagnetic iron oxide (SPIO) nanoparticles injected as a tracer in early-stage cancer patients can be detected accurately by a handheld magnetometer and optimize the lymphatic mapping of sentinel lymph nodes (SLNs). We proved that this detection method is not inferior when compared to pelvic lymphadenectomy, which is the standard of care. The diagnostic accuracy parameters of the SPIO detection of metastatic SLNs evaluated by the Receiver Operating Characteristic (ROC) curve analysis with the area under the ROC curve (AUC) demonstrated a sensitivity of 100% and an AUC of 1.0. The SPIO method was determined to be safe (no adverse events reported), accurate (magnetic sensing remains accurate through its use), and reliable (SPIO retains its signal during surgical management). View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (38)

  • Systematic Review
  • Open Access
894 Views
16 Pages

Potential Applications of PRP-Enhanced Polybutylene Succinate Graft as Vascular Access for Chemotherapy in Oncological Patients: A Systematic Review

  • Andrea Gottardo,
  • Giulia Bonventre,
  • Tancredi Didier Bazan Russo,
  • Pietro Zanatta,
  • Giulia Lo Monte,
  • Valerio Gristina,
  • Antonio Galvano,
  • Antonio Russo and
  • Attilio Ignazio Lo Monte

This systematic review aimed to evaluate the potential of combining platelet-rich plasma (PRP) and polybutylene succinate (PBS) for the development of vascular grafts in patients undergoing chemotherapy. Relevant articles published in English or Ital...

  • Article
  • Open Access
1 Citations
1,411 Views
24 Pages

Developing Bioengineered 3D-Printed Composite Scaffolds with Antimicrobial Potential for Bone Tissue Regeneration

  • Andreea Trifan,
  • Eduard Liciu,
  • Cristina Busuioc,
  • Izabela-Cristina Stancu,
  • Adela Banciu,
  • Carmen Nicolae,
  • Mihai Dragomir,
  • Doru-Daniel Cristea,
  • Rosina-Elena Sabău and
  • David-Andrei Nițulescu
  • + 1 author

This research activity proposes to produce composite hydrogel–bioactive glass. The primary purpose of this research is to develop and optimize 3D-printed scaffolds using doped bioglass, aimed at enhancing bone regeneration in bone defects. The...

  • Review
  • Open Access
1 Citations
1,830 Views
17 Pages

What Are the Best Biocompatible Materials for Extracorporeal Membrane Oxygenation

  • Junya Hagiwara,
  • Jeffrey D. DellaVolpe and
  • Yuichi Matsuzaki

Extracorporeal membrane oxygenation (ECMO) is a crucial life support therapy for patients with severe cardiac and respiratory failure. However, the complications associated with venoarterial ECMO (VA-ECMO), including thrombus formation, bleeding, and...

  • Article
  • Open Access
1 Citations
2,190 Views
18 Pages

The Impact of Different Fiber Placement Techniques on the Fracture Resistance of Premolars Restored with Direct Resin Composite, In Vitro Study

  • Reham Hesham Ibrahim,
  • Dina Wafik ElKassas,
  • Sameh Mahmoud Nabih,
  • Mennatallah Naguib Salem and
  • Rasha Haridy

Fiber-reinforced composites (FRCs) are recognized for enhancing the fracture resistance of structurally compromised teeth. However, the optimal orientation and placement of fibers in direct resin composite restorations remain under debate. This study...

  • Article
  • Open Access
1,513 Views
19 Pages

The Influence of the Machining Drill and Direction of Rotation on the Surfaces of Ti6Al4V Dental Implants Subjected to Implantoplasty

  • Esteban Padullés-Gaspar,
  • Francisco Real-Voltas,
  • Esteban Padullés-Roig,
  • Miguel Punset,
  • Guillermo Cabanes,
  • Pablo Fernández and
  • Javier Gil

Implantoplasty is widely used to treat peri-implantitis by removing biofilms from Ti6Al4V dental implants using rotating drills. This study examined the effects of diamond and tungsten carbide drills, and rotation direction (clockwise/counterclockwis...

  • Article
  • Open Access
1,278 Views
11 Pages

Effect of Thermal Aging on Color Stability and Mechanical Properties of High-Density CAD/CAM Polymers Utilized for Provisional Restorations

  • Rasha Alharthi,
  • Ali Robaian Alqahtani,
  • Abdullah Mohammed Alshehri,
  • Abdulrahman Almalki,
  • Heba Wageh Abozaed,
  • Eman Mohamed Raffat Hussein and
  • Tarek Ahmed Soliman

Background: This study evaluated and compared the effects of thermal aging on the color stability and mechanical properties of CAD/CAM polymers utilized for provisional restorations. Material and Methods: Three CAD/CAM polymers in this study: CAD-Tem...

  • Article
  • Open Access
1,225 Views
22 Pages

Enhanced Osteogenesis and Antibacterial Properties of Ketoprofen-Loaded MgCu-MOF74-Coated Titanium Alloy for Bone Implant

  • Ziqing Duan,
  • Yifeng Yao,
  • Jiamin Liu,
  • Yanni Tan,
  • Qingge Wang,
  • Man Fang,
  • Aqsa Kanwal,
  • Shuqiao Cheng,
  • Juan Huang and
  • Hong Wu

To address the dual clinical challenges of poor osseointegration and inadequate analgesia caused by postoperative infections in traditional titanium implants, this study proposes a multifunctional synergistic strategy based on metal—organic fra...

  • Article
  • Open Access
2,046 Views
17 Pages

Objective: This study aims to evaluate the stress distribution on endodontically treated anterior teeth restored using different restorative materials and different post lengths versus endocrowns employing finite element analysis (FEA). Methods: An e...

  • Article
  • Open Access
1,184 Views
21 Pages

A Modular Biomimetic Preclinical Platform to Elucidate the Interaction Between Cancer Cells and the Bone Metastatic Niche

  • Claudia Cocchi,
  • Massimiliano Dapporto,
  • Ania Naila Guerrieri,
  • Chiara Liverani,
  • Marta Tavoni,
  • Chiara Bellotti,
  • Chiara Spadazzi,
  • Anna Tampieri,
  • Marco Gambarotti and
  • Giacomo Miserocchi
  • + 6 authors

Breast cancer (BC) frequently metastasizes to bone, leading to poor patient prognosis. The infiltration of cancer cells in bone impairs its homeostasis, triggering a pathological interaction between tumors and resident cells. Preclinical models able...

  • Article
  • Open Access
1 Citations
979 Views
23 Pages

Electrospinning of Bovine Split Hide Collagen and Collagen/Glycosaminoglycan for a Study of Stem Cell Adhesion and Proliferation on the Mats: Influence of Composition and Structural Morphology

  • Todorka G. Vladkova,
  • Dilyana N. Gospodinova,
  • Peter D. Dineff,
  • Milena Keremidarska-Markova,
  • Kamelia Hristova-Panusheva and
  • Natalia Krasteva

Electrospun collagen-based fibrous mats are of increasing interest for cell culture, regenerative medicine, and tissue engineering. The focus of this investigation is on the assessment of the electrospinning ability of bovine split hide collagen (BSH...

of 4

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
J. Funct. Biomater. - ISSN 2079-4983Creative Common CC BY license