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Journal of Functional Biomaterials, Volume 10, Issue 1

March 2019 - 16 articles

Cover Story: Brushite (DCPD) is among the possible precursors of the inorganic phase of the hard tissues of vertebrates. Herein, we investigated the role of aspartic acid (ASP) and poly-aspartic acid (PASP), as models of the acidic macromolecules of biomineralized tissues, on the synthesis and hydrolysis of DCPD. The results indicate that ASP is not significantly incorporated into DCPD, whereas functionalization with PASP occurs up to about 2.3 wt.%. PASP shows a greater influence than ASP also on the hydrolysis of DCPD into more stable phases, thanks to the cooperative action of the carboxylate groups and to its good fit with DCPD structure. View this paper.
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Articles (16)

  • Review
  • Open Access
35 Citations
10,263 Views
18 Pages

The conventional applicability of biomaterials in the field of bone tissue engineering takes into consideration several key parameters to achieve desired results for prospective translational use. Hence, several engineering strategies have been devel...

  • Article
  • Open Access
42 Citations
9,654 Views
14 Pages

Fabrication of Porous Bone Scaffolds Using Alginate and Bioactive Glass

  • Jonathan Hatton,
  • Graham Roy Davis,
  • Abdel-Hamid I. Mourad,
  • Nizamudeen Cherupurakal,
  • Robert G. Hill and
  • Sahar Mohsin

Porous composite scaffold using an alginate and bioactive glass ICIE16M was synthesized by a simple freeze-drying technique. The scaffold was characterized using compression testing, Fourier-transform infrared spectroscopy (FTIR), differential scanni...

  • Article
  • Open Access
34 Citations
8,586 Views
11 Pages

Six-Month Color Stability Assessment of Two Calcium Silicate-Based Cements Used in Regenerative Endodontic Procedures

  • Paulo J. Palma,
  • Joana A. Marques,
  • Rui I. Falacho,
  • Eder Correia,
  • Alexandra Vinagre,
  • João Miguel Santos and
  • João C. Ramos

Aim: The purpose of the present study is to assess the color stability of two calcium silicate-based cements (CSCs) used in regenerative endodontic procedures (REPs). Methods: A total of 40 acrylic single-rooted transparent teeth, with immature apex,...

  • Article
  • Open Access
21 Citations
7,372 Views
16 Pages

Effect of Calcium Precursor on the Bioactivity and Biocompatibility of Sol-Gel-Derived Glasses

  • Alejandra Ruiz-Clavijo,
  • Andrew P. Hurt,
  • Arun K. Kotha and
  • Nichola J. Coleman

This study investigated the impact of different calcium reagents on the morphology, composition, bioactivity and biocompatibility of two-component (CaO-SiO2) glasses produced by the Stöber process with respect to their potential application in g...

  • Article
  • Open Access
19 Citations
8,603 Views
21 Pages

A synthetic technique inspired by the biomineralisation process in nacre has been previously reported to be effective in replicating the nanostructural elements of nacre in 2D chitosan hydrogel films. Here we evaluate the applicability of this synthe...

  • Article
  • Open Access
23 Citations
8,397 Views
12 Pages

Dicalcium phosphate dihydrate (DCPD) is one of the mineral phases indicated as possible precursors of biological apatites and it is widely employed in the preparation of calcium phosphate bone cements. Herein, we investigated the possibility to funct...

  • Feature Paper
  • Review
  • Open Access
11 Citations
7,377 Views
34 Pages

Biomaterial enhanced regeneration (BER) falls mostly under the broad heading of Tissue Engineering: the use of materials (synthetic and natural) usually in conjunction with cells (both native and genetically modified as well as stem cells) and/or bio...

  • Feature Paper
  • Review
  • Open Access
60 Citations
10,864 Views
7 Pages

3D printing of polymers can now be considered as a common processing technology for the development of biomaterials. These can be constituted out of polymeric abiotic material alone or can be co-printed with living cells. However, the adaptive and sh...

  • Retraction
  • Open Access
1 Citations
6,632 Views

Due to human error, the authors included some of the experimental data in this article [...]

  • Feature Paper
  • Article
  • Open Access
19 Citations
7,237 Views
12 Pages

Evaluation of Osteoconduction of Biphasic Calcium Phosphate Ceramic in the Calvaria of Rats: Microscopic and Histometric Analysis

  • Igor de Oliveira Puttini,
  • Pier Paolo Poli,
  • Carlo Maiorana,
  • Igor Rodrigues de Vasconcelos,
  • Luis Eduardo Schmidt,
  • Luara Teixeira Colombo,
  • Henrique Hadad,
  • Gabriel Mulinari dos Santos,
  • Paulo Sergio Perri de Carvalho and
  • Francisley Ávila Souza

(1) Background: Evaluate the osteoconduction capability of a biphasic calcium phosphate (BCP) ceramic composed of hydroxyapatite and β-tricalcium phosphate 60%/40% in a rat model. (2) Methods: In the calvarial bone of 54 adult male rats, 7-mm di...

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J. Funct. Biomater. - ISSN 2079-4983