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Journal of Functional Biomaterials, Volume 10, Issue 1

March 2019 - 16 articles

Cover Story: Brushite (DCPD) is among the possible precursors of the inorganic phase of the hard tissues of vertebrates. Herein, we investigated the role of aspartic acid (ASP) and poly-aspartic acid (PASP), as models of the acidic macromolecules of biomineralized tissues, on the synthesis and hydrolysis of DCPD. The results indicate that ASP is not significantly incorporated into DCPD, whereas functionalization with PASP occurs up to about 2.3 wt.%. PASP shows a greater influence than ASP also on the hydrolysis of DCPD into more stable phases, thanks to the cooperative action of the carboxylate groups and to its good fit with DCPD structure. View this paper.
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Articles (16)

  • Article
  • Open Access
5 Citations
6,990 Views
14 Pages

Assessment of Dental Implants with Modified Calcium-Phosphate Surface in a Multicenter, Prospective, Non-Interventional Study: Results up to 50 Months of Follow-Up

  • Carles Subirà-Pifarré,
  • Cristina Masuet-Aumatell,
  • Carlos Rodado Alonso,
  • Ricardo Medina Madrid and
  • Cosimo Galletti

Prescription of implant treatments is very widespread at present, mainly due to the low rate of annual loss and, to date, few studies have assessed their survival in the routine clinical practice of dentistry. The purpose of this observational study...

  • Review
  • Open Access
386 Citations
17,998 Views
15 Pages

Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies

  • Eleonora Calzoni,
  • Alessio Cesaretti,
  • Alice Polchi,
  • Alessandro Di Michele,
  • Brunella Tancini and
  • Carla Emiliani

Polymer nanoparticles (NPs) represent one of the most innovative non-invasive approaches for drug delivery applications. NPs main objective is to convey the therapeutic molecule be they drugs, proteins, or nucleic acids directly into the target organ...

  • Review
  • Open Access
155 Citations
15,994 Views
36 Pages

Periodontal diseases involve injuries to the supporting structures of the tooth and, if left untreated, can lead to the loss of the tooth. Regenerative periodontal therapies aim, ideally, at healing all the damaged periodontal tissues and represent a...

  • Article
  • Open Access
16 Citations
7,136 Views
12 Pages

Chronic dermal lesions, such as pressure ulcers, are difficult to heal. Degradable tissue scaffold systems can be employed to serve as a provisional matrix for cellular ingrowth and facilitate regenerative healing during degradation. Degradable regen...

  • Review
  • Open Access
26 Citations
8,780 Views
24 Pages

A Critical Review on Selected External Physical Cues and Modulation of Cell Behavior: Magnetic Nanoparticles, Non-thermal Plasma and Lasers

  • Barbora Smolková,
  • Mariia Uzhytchak,
  • Anna Lynnyk,
  • Šárka Kubinová,
  • Alexandr Dejneka and
  • Oleg Lunov

Physics-based biomedical approaches have proved their importance for the advancement of medical sciences and especially in medical diagnostics and treatments. Thus, the expectations regarding development of novel promising physics-based technologies...

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J. Funct. Biomater. - ISSN 2079-4983