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Journal of Clinical Medicine, Volume 6, Issue 11

November 2017 - 9 articles

Cover Story: We have not infrequently found water retention and hyponatremia in non-endocrine disorders. Sustained elevation of arginine vasopressin is profoundly involved in pathogenesis of impaired water excretion. If hyponatremia is a consequence of water retention in edematous diseases, hyponatremia predicts their long-term outcome. The present review summarizes recent understanding of pathological role of exaggerated release of arginine vasopressin in non-endocrine disorders. View this paper
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Articles (9)

  • Feature Paper
  • Review
  • Open Access
30 Citations
5,660 Views
6 Pages

Knee and Ankle Arthroplasty in Hemophilia

  • Luigi Piero Solimeno and
  • Gianluigi Pasta

22 November 2017

Today, major surgical procedures can be safely performed in hemophilic patients with chronic arthropathy, using available factor concentrates. In this setting, total knee replacement is considered the “gold standard”, while the use of total ankle rep...

  • Article
  • Open Access
4 Citations
6,464 Views
9 Pages

Inter-Rater Reliability of Provider Interpretations of Irritable Bowel Syndrome Food and Symptom Journals

  • Jasmine Zia,
  • Chia-Fang Chung,
  • Kaiyuan Xu,
  • Yi Dong,
  • Jeanette M. Schenk,
  • Kevin Cain,
  • Sean Munson and
  • Margaret M. Heitkemper

4 November 2017

There are currently no standardized methods for identifying trigger food(s) from irritable bowel syndrome (IBS) food and symptom journals. The primary aim of this study was to assess the inter-rater reliability of providers’ interpretations of IBS jo...

  • Feature Paper
  • Review
  • Open Access
11 Citations
4,664 Views
10 Pages

3 November 2017

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder, with the characteristic symptoms of chronic abdominal pain and altered bowel habits (diarrhea, constipation, or both). IBS is a highly prevalent condition, which negatively aff...

  • Article
  • Open Access
12 Citations
6,091 Views
9 Pages

Gender and Weight Influence Quality of Life in Irritable Bowel Syndrome

  • LeeAnne B. Sherwin,
  • Onyinyechi M. Ozoji,
  • Christina M. Boulineaux,
  • Paule V. Joseph,
  • Nicolaas H. Fourie,
  • Sarah K. Abey,
  • Xuemin Zhang and
  • Wendy A. Henderson

1 November 2017

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by abdominal pain and bowel dysfunction in the absence of structural abnormality. Diagnosis can be challenging and often leads to extensive medical tests, non-effectiv...

  • Feature Paper
  • Review
  • Open Access
5 Citations
6,465 Views
11 Pages

31 October 2017

Exaggerated release of arginine vasopressin (AVP) is profoundly involved in impaired water excretion and related hyponatremia. Such disorders underlie syndromes of inappropriate secretion of antidiuretic hormone (SIADH) and edematous diseases, such a...

  • Feature Paper
  • Review
  • Open Access
45 Citations
22,506 Views
16 Pages

Pharmacotherapy for Irritable Bowel Syndrome

  • Michael Camilleri and
  • Alexander C. Ford

27 October 2017

Irritable bowel syndrome (IBS) is a disorder of the brain-gut axis; the pathophysiological mechanisms include altered colonic motility, bile acid metabolism, neurohormonal regulation, immune dysfunction, alterations in the epithelial barrier and secr...

  • Feature Paper
  • Review
  • Open Access
66 Citations
11,305 Views
17 Pages

27 October 2017

Oxidative stress arises when cellular antioxidant defences become overwhelmed by a surplus generation of reactive oxygen species (ROS). Once this occurs, many cellular biomolecules such as DNA, lipids, and proteins become susceptible to free radical-...

  • Feature Paper
  • Review
  • Open Access
401 Citations
37,050 Views
8 Pages

26 October 2017

Functional gastrointestinal disorders (FGIDs) account for at least 40% of all referrals to gastroenterologists. Of the 33 recognized adult FGIDs, irritable bowel syndrome (IBS) is the most prevalent, with a worldwide prevalence estimated at 12%. IBS...

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J. Clin. Med. - ISSN 2077-0383