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Takamatsu, H. Comparison of Minimal Residual Disease Detection by Multiparameter Flow Cytometry, ASO-qPCR, Droplet Digital PCR, and Deep Sequencing in Patients with Multiple Myeloma Who Underwent Autologous Stem Cell Transplantation. J. Clin. Med. 2017, 6, 91
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Ultrasound for Early Detection of Joint Disease in Patients with Hemophilic Arthropathy
Open AccessFeature PaperReview

Knee and Ankle Arthroplasty in Hemophilia

Division of Orthopaedic Surgery and Traumatology, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Via F. Sforza, 28, 20122 Milan, Italy
Author to whom correspondence should be addressed.
J. Clin. Med. 2017, 6(11), 107;
Received: 11 May 2017 / Revised: 30 October 2017 / Accepted: 1 November 2017 / Published: 22 November 2017
(This article belongs to the Special Issue Outstanding Advances in Hemophilia Therapies)
Today, major surgical procedures can be safely performed in hemophilic patients with chronic arthropathy, using available factor concentrates. In this setting, total knee replacement is considered the “gold standard”, while the use of total ankle replacement is still debated. Indeed, the unsatisfactory results obtained with the previous available design of implants did not raise enthusiasm as knee or hip replacement. Recently, the introduction of new implant designs and better reported outcomes have renewed the interest in total ankle replacement in people with hemophilia. In this review, the role of replacement surgery in the treatment of chronic hemophilic arthropathy will be described. View Full-Text
Keywords: hemophilia; knee; ankle; arthroplasty; replacement hemophilia; knee; ankle; arthroplasty; replacement
MDPI and ACS Style

Solimeno, L.P.; Pasta, G. Knee and Ankle Arthroplasty in Hemophilia. J. Clin. Med. 2017, 6, 107.

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