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Journal of Clinical Medicine, Volume 11, Issue 18

September-2 2022 - 240 articles

Cover Story: Acute idiopathic blind spot enlargement syndrome (AIBSES) predominantly affects young adults and is often misdiagnosed as optic neuritis because of low awareness. Only around 100 cases have been published. A careful taking of history and unprejudiced ophthalmological workup help in diagnosing AIBSES in patients with unilateral visual field loss in the blind spot area, acute onset photopsia, and funduscopically few or no optic disc changes. As it is a disease of the outer retina, optical coherence tomography (OCT) has become the gold standard in diagnosing AIBSES. In our case series, we present three consecutive patients with AIBSES that are followed prospectively with and without steroid therapy. All of the patients reported full recovery of their symptoms and partial restoration of the outer retinal layer anatomy. View this paper
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Articles (240)

  • Article
  • Open Access
8 Citations
2,598 Views
10 Pages

Muscular Strength and Carotid Intima–Media Thickness in Physically Fit Young Adults: The CHIEF Atherosclerosis Study

  • Gen-Min Lin,
  • Kun-Zhe Tsai,
  • Yun-Chen Chang,
  • Wei-Chun Huang,
  • Xuemei Sui and
  • Carl J. Lavie

16 September 2022

Background: Greater muscular strength (MusS) has been found to have an inverse association with subclinical atherosclerosis in children, as well as with mortality from cardiovascular diseases (CVDs) in middle-aged and elderly individuals. However, th...

  • Article
  • Open Access
1 Citations
2,779 Views
14 Pages

Datterino Trial: A Double Blind, Randomized, Controlled, Crossover, Clinical Trial on the Use of Hydroponic Cultivated Tomato Sauce in Systemic Nickel Allergy Syndrome

  • Angela Rizzi,
  • Raffaella Chini,
  • Serena Porcari,
  • Carlo Romano Settanni,
  • Eleonora Persichetti,
  • Vincenzina Mora,
  • Caterina Fanali,
  • Alessia Leonetti,
  • Giuseppe Parrinello and
  • Franziska Michaela Lohmeyer
  • + 4 authors

16 September 2022

A low-nickel (Ni) diet, a key treatment for Systemic Nickel Allergy Syndrome (SNAS), is difficult in the long term and strongly impacts quality of life (QoL). Hydroponic agriculture could be an alternative to allow the reintroduction of tomato, an es...

  • Article
  • Open Access
2 Citations
2,182 Views
12 Pages

Knee Kinematic Patterns and Early Cartilage Lesion Characteristics in Patients with Anterior Cruciate Ligament Reconstruction

  • Xiaolong Zeng,
  • Jiajun Zeng,
  • Jinpeng Lin,
  • Lingchuang Kong,
  • Haobin Chen,
  • Guoqing Zhong,
  • Limin Ma,
  • Yu Zhang and
  • Wenhan Huang

16 September 2022

Specific knee kinematic alterations have been theorized to correlate with the progression of cartilage degeneration, and therefore, post-traumatic osteoarthritis in patients with anterior cruciate ligament reconstruction (ACLR). However, how specific...

  • Article
  • Open Access
3 Citations
1,877 Views
8 Pages

Impact of Elevated LDH on Cystatin C-Based Glomerular Filtration Rate Estimates in Patients with Cancer

  • Enver Aydilek,
  • Manuel Wallbach,
  • Michael Koziolek,
  • Gerald Georg Wulf and
  • Nils Brökers

16 September 2022

Background: The determination of renal function is crucial for the clinical management of patients with cancer. The glomerular filtration rate (GFR) serves as a key parameter, estimated by creatinine clearance determination in 24-h collected urine (C...

  • Article
  • Open Access
12 Citations
3,950 Views
10 Pages

Peripheral Nerve Block for Pain Management after Total Hip Arthroplasty: A Retrospective Study with Propensity Score Matching

  • Heon Jung Park,
  • Kwan Kyu Park,
  • Jun Young Park,
  • Bora Lee,
  • Yong Seon Choi and
  • Hyuck Min Kwon

16 September 2022

This study aimed to evaluate the effect of a peripheral nerve block (PNB) on immediate postoperative analgesia and the early functional outcomes for patients who underwent total hip arthroplasty (THA). From January 2016 to August 2021, 353 patients w...

  • Article
  • Open Access
10 Citations
4,086 Views
12 Pages

Antithrombotic Treatment Patterns of Patients with Symptomatic Peripheral Arterial Occlusive Disease in Germany: Evidence from Health Insurance Claims Data

  • Frederik Peters,
  • Jenny Kuchenbecker,
  • Laura Acar,
  • Ursula Marschall,
  • Helmut L’Hoest,
  • Fabien Lareyre,
  • Konstantinos Spanos and
  • Christian-Alexander Behrendt

16 September 2022

Objectives: Patients with peripheral arterial occlusive disease (PAOD) are at risk of worsening limb symptoms, major adverse cardiovascular events and exhibit an impaired life expectancy. There is a lack of evidence on the extent of pharmacological s...

  • Systematic Review
  • Open Access
20 Citations
3,445 Views
16 Pages

16 September 2022

There is mounting evidence that statin use is beneficial for COVID-19 outcomes. We performed a systematic review and meta-analysis to evaluate the association between statin use and mortality, intensive care unit (ICU) admission and mechanical ventil...

  • Article
  • Open Access
8 Citations
3,335 Views
9 Pages

16 September 2022

This monocentric, single-blinded, randomized controlled noninferiority trial investigated the analgesic efficacy of erector spinae plane block (ESPB) combined with intercostal nerve block (ICNB) compared to that of thoracic paravertebral block (PVB)...

  • Article
  • Open Access
2 Citations
2,996 Views
11 Pages

Evaluation of a Triage Checklist for Mild COVID-19 Outpatients in Predicting Subsequent Emergency Department Visits and Hospitalization during the Isolation Period: A Single-Center Retrospective Study

  • Yasuhiro Tanaka,
  • Kazuko Yamamoto,
  • Shimpei Morimoto,
  • Takeshi Nabeshima,
  • Kayoko Matsushima,
  • Hiroshi Ishimoto,
  • Nobuyuki Ashizawa,
  • Tatsuro Hirayama,
  • Kazuaki Takeda and
  • Hiroshi Gyotoku
  • + 22 authors

16 September 2022

Managing mild illness in COVID-19 and predicting progression to severe disease are concerning issues. Here, we investigated the outcomes of Japanese patients with mild COVID-19, and identified triage risk factors for further hospitalization and emerg...

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J. Clin. Med. - ISSN 2077-0383