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Antioxidants, Volume 9, Issue 12

December 2020 - 143 articles

Cover Story: The present review deals with reactive oxygen and nitrogen species, as they have emerged over the past centuries. It describes their discovery in biological systems, their metabolic fate, their role in host defense, their pathogenic potential, and their physiological role in redox regulation and signaling. The article ends with a critical discussion of the inflationary use of poorly defined terms such as ROS, NOS, antioxidants, and stress. View this paper
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Articles (143)

  • Article
  • Open Access
26 Citations
5,129 Views
13 Pages

Quantitative Spatiotemporal Mapping of Lipid and Protein Oxidation in Mayonnaise

  • Suyeon Yang,
  • Aletta A. Verhoeff,
  • Donny W. H. Merkx,
  • John P. M. van Duynhoven and
  • Johannes Hohlbein

15 December 2020

Lipid oxidation in food emulsions is mediated by emulsifiers in the water phase and at the oil–water interface. To unravel the physico-chemical mechanisms and to obtain local lipid and protein oxidation rates, we used confocal laser scanning mi...

  • Article
  • Open Access
8 Citations
2,810 Views
14 Pages

Associations between Lifestyle Factors and Vitamin E Metabolites in the General Population

  • Leon G. Martens,
  • Jiao Luo,
  • Fleur L. Meulmeester,
  • Nadia Ashrafi,
  • Esther Winters van Eekelen,
  • Renée de Mutsert,
  • Dennis O. Mook-Kanamori,
  • Frits R. Rosendaal,
  • Ko Willems van Dijk and
  • Kevin Mills
  • + 2 authors

15 December 2020

The antioxidant vitamin E (α-tocopherol, α-TOH) protects lipids from oxidation by reactive oxygen species. We hypothesized that lifestyle factors associate with vitamin E metabolism marked by urinary α-tocopheronolactone hydroquinon...

  • Review
  • Open Access
53 Citations
8,490 Views
21 Pages

Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems

  • Miroslav Barancik,
  • Branislav Kura,
  • Tyler W. LeBaron,
  • Roberto Bolli,
  • Jozef Buday and
  • Jan Slezak

15 December 2020

The increased production of reactive oxygen species and oxidative stress are important factors contributing to the development of diseases of the cardiovascular and central nervous systems. Molecular hydrogen is recognized as an emerging therapeutic,...

  • Review
  • Open Access
17 Citations
11,618 Views
15 Pages

Miracle Berry as a Potential Supplement in the Control of Metabolic Risk Factors in Cancer

  • Marta Gómez de Cedrón,
  • Sonia Wagner,
  • Marina Reguero,
  • Adrián Menéndez-Rey and
  • Ana Ramírez de Molina

15 December 2020

The increased incidence of chronic diseases related to altered metabolism has become a social and medical concern worldwide. Cancer is a chronic and multifactorial disease for which, together with genetic factors, environmental factors are crucial. A...

  • Review
  • Open Access
258 Citations
12,466 Views
21 Pages

15 December 2020

Activated hepatic stellate cells (HSCs) and myofibroblasts are the main producers of extracellular matrix (ECM) proteins that form the fibrotic tissue that leads to hepatic fibrosis. Reactive oxygen species (ROS) can directly activate HSCs or induce...

  • Article
  • Open Access
4 Citations
3,697 Views
16 Pages

14 December 2020

Antioxidant effects of statins have been implicated in the reduction in microvascular permeability and edema formation in experimental and clinical studies. Bradykinin (Bk)-induced increases in microvascular permeability are potentiated by IL-1β...

  • Article
  • Open Access
37 Citations
3,886 Views
16 Pages

14 December 2020

Emerging evidence suggests that epigenetic mechanisms such as histone modification are crucially involved in the pathophysiology of acute kidney injury (AKI). The histone acetyltransferase p300 regulates several biological processes through the acety...

  • Article
  • Open Access
6 Citations
2,398 Views
16 Pages

Influence of the Location of Ascorbic Acid in Walnut Oil Spray-Dried Microparticles with Outer Layer on the Physical Characteristics and Oxidative Stability

  • Denisse Cáceres,
  • Begoña Giménez,
  • Gloria Márquez-Ruiz,
  • Francisca Holgado,
  • Cristina Vergara,
  • Patricio Romero-Hasler,
  • Eduardo Soto-Bustamante and
  • Paz Robert

14 December 2020

Purified walnut oil (PWO) microparticles with Capsul® (C, encapsulating agent), sodium alginate (SA) as outer layer and ascorbic acid (AA) as oxygen scavenger were obtained by spray drying using a three-fluid nozzle. AA was incorporated in the in...

  • Article
  • Open Access
29 Citations
5,125 Views
19 Pages

14 December 2020

Background: The mode of action of Phoenix dactylifera seed extract in skin care has never been explored. Methods: P. dactylifera L. seeds were extracted by ultrasonic extraction. The antioxidant characteristics of the extract were determined by 2,2-d...

  • Article
  • Open Access
17 Citations
5,146 Views
16 Pages

14 December 2020

Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxid...

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Antioxidants - ISSN 2076-3921