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Antioxidants, Volume 13, Issue 1

January 2024 - 134 articles

Cover Story: Heavy metals pose a serious threat to human health. Recent studies have linked damage associated with heavy metal exposure to oxidative stress and aging, and have identified common pathways, such as apoptosis, endoplasmic reticulum stress, and mitochondrial stress. Chelation therapy is a traditional approach to heavy metal-induced disorders, but recently the focus has shifted to antioxidants, which have been proven to be more effective treatments. This review discusses the molecular basis of heavy metal toxicity, its correlation with aging, and its clinical significance, as well as the role of antioxidants and other protective agents against heavy metal damage, reflecting the evolving paradigm in therapeutic approaches. View this paper
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Articles (134)

  • Article
  • Open Access
15 Citations
3,647 Views
17 Pages

Pyrroloquinoline Quinone Improves Ram Sperm Quality through Its Antioxidative Ability during Storage at 4 °C

  • Zhendong Zhu,
  • Wenjia Li,
  • Qitai Yang,
  • Haolong Zhao,
  • Weijing Zhang,
  • Adedeji O. Adetunji,
  • S. A. Masudul Hoque,
  • Xin Kou and
  • Lingjiang Min

15 January 2024

Sperm motility is an important factor in the migration of sperm from the uterus to the oviduct. During sperm preservation in vitro, sperm generates excessive ROS that damages its function. This study aims to investigate whether the addition of pyrrol...

  • Article
  • Open Access
2 Citations
2,286 Views
20 Pages

Dietary Marine Oils Selectively Decrease Obesogenic Diet-Derived Carbonylation in Proteins Involved in ATP Homeostasis and Glutamate Metabolism in the Rat Cerebellum

  • Francisco Moreno,
  • Lucía Méndez,
  • Ana Raner,
  • Bernat Miralles-Pérez,
  • Marta Romeu,
  • Sara Ramos-Romero,
  • Josep Lluís Torres and
  • Isabel Medina

15 January 2024

The regular intake of diets high in saturated fat and sugars increases oxidative stress and has been linked to cognitive decline and premature brain aging. The cerebellum is highly vulnerable to oxidative stress and thus, obesogenic diets might be pa...

  • Article
  • Open Access
2 Citations
3,204 Views
18 Pages

The Amazonian Camu-Camu Fruit Modulates the Development of Drosophila melanogaster and the Neural Function of Adult Flies under Oxidative Stress Conditions

  • Elize Aparecida Santos Musachio,
  • Rafaela Garay Pires,
  • Eliana Jardim Fernandes,
  • Stefani Andrade,
  • Luana Barreto Meichtry,
  • Dieniffer Espinosa Janner,
  • Graziela Moro Meira,
  • Euler Esteves Ribeiro,
  • Fernanda Barbisan and
  • Ivana Beatrice Mânica da Cruz
  • + 1 author

15 January 2024

Camu-camu (Myrciaria dubia) is known for its antioxidant properties, although little is known about its developmental safety effects, particularly on adult neural function under basal redox and oxidative stress conditions. Therefore, this study sough...

  • Article
  • Open Access
5 Citations
2,980 Views
15 Pages

C2CD4B Evokes Oxidative Stress and Vascular Dysfunction via a PI3K/Akt/PKCα–Signaling Pathway

  • Paola Di Pietro,
  • Angela Carmelita Abate,
  • Valeria Prete,
  • Antonio Damato,
  • Eleonora Venturini,
  • Maria Rosaria Rusciano,
  • Carmine Izzo,
  • Valeria Visco,
  • Michele Ciccarelli and
  • Carmine Vecchione
  • + 1 author

14 January 2024

High glucose–induced endothelial dysfunction is an important pathological feature of diabetic vasculopathy. While genome-wide studies have identified an association between type 2 diabetes mellitus (T2DM) and increased expression of a C2 calciu...

  • Review
  • Open Access
44 Citations
5,194 Views
30 Pages

Bioactive Components, Applications, Extractions, and Health Benefits of Winery By-Products from a Circular Bioeconomy Perspective: A Review

  • Oana Emilia Constantin,
  • Florina Stoica,
  • Roxana Nicoleta Rațu,
  • Nicoleta Stănciuc,
  • Gabriela Elena Bahrim and
  • Gabriela Râpeanu

14 January 2024

Significant waste streams produced during winemaking include winery by-products such as pomace, skins, leaves, stems, lees, and seeds. These waste by-products were frequently disposed of in the past, causing resource waste and environmental issues. H...

  • Review
  • Open Access
3 Citations
3,539 Views
21 Pages

Application of Multi-Omics Technologies to the Study of Phytochromes in Plants

  • Shumei Wu,
  • Yue Gao,
  • Qi Zhang,
  • Fen Liu and
  • Weiming Hu

14 January 2024

Phytochromes (phy) are distributed in various plant organs, and their physiological effects influence plant germination, flowering, fruiting, and senescence, as well as regulate morphogenesis throughout the plant life cycle. Reactive oxygen species (...

  • Review
  • Open Access
38 Citations
11,179 Views
30 Pages

Silymarin and Inflammation: Food for Thoughts

  • Peter F. Surai,
  • Anton Surai and
  • Katie Earle-Payne

14 January 2024

Inflammation is a vital defense mechanism, creating hostile conditions for pathogens, preventing the spread of tissue infection and repairing damaged tissues in humans and animals. However, when inflammation resolution is delayed or compromised as a...

  • Article
  • Open Access
3 Citations
2,791 Views
13 Pages

PhInd—Database on Polyphenol Content in Agri-Food By-Products and Waste: Features of the Database

  • Nemanja Teslić,
  • Milica Pojić,
  • Alena Stupar,
  • Anamarija Mandić,
  • Branimir Pavlić and
  • Aleksandra Mišan

12 January 2024

Timely access to topic-relevant datasets is of paramount importance for the development of any successful strategy (food waste reduction strategy), since datasets illuminate opportunities, challenges and development paths. PhInd is the first comprehe...

  • Article
  • Open Access
1 Citations
2,479 Views
19 Pages

The Fecal Redox Potential in Healthy and Diarrheal Pigs and Their Correlation with Microbiota

  • Ni Feng,
  • Rongying Xu,
  • Dongfang Wang,
  • Lian Li,
  • Yong Su and
  • Xiaobo Feng

12 January 2024

The redox potential plays a critical role in sustaining the stability of gut microbiota. This study measured the fecal redox potential in healthy and diarrheal pigs using direct and dilution methods and investigated their correlation with microbiota....

  • Review
  • Open Access
10 Citations
5,445 Views
15 Pages

12 January 2024

Acute respiratory distress syndrome (ARDS) is a life-threatening event that occurs in patients suffering from bacterial, fungal, or viral sepsis. Research performed over the last five decades showed that ARDS is a consequence of severe unrestrained s...

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Antioxidants - ISSN 2076-3921