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Brain Sciences, Volume 15, Issue 3

March 2025 - 110 articles

Cover Story: Sleep appears to have a central role in Freud’s original model, since dreaming is considered the guardian of sleep. The function of dreaming is to protect sleep from disruption, thereby preserving its biological integrity. Freud also recognized sleep as an active process, given that human beings voluntarily withdraw from the external world to sleep. The discovery of REM sleep in the 1950s led psychoanalysts to view sleep as the necessary backdrop against which dreaming occurs. Although Freud dismissed the clinical importance of sleep disturbances, authors have since suggested that sleep disturbances might have specific psychological significance. Thanks to Freud’s work, the desire to sleep assumes an important role as a psychological, active factor that contributes to the occurrence and function of sleep. View this paper
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Articles (110)

  • Systematic Review
  • Open Access
1 Citations
1,507 Views
13 Pages

Skin Lesions as Signs of Neuroenhancement in Sport

  • Sorana-Cristiana Popescu,
  • Roman Popescu,
  • Vlad Voiculescu and
  • Carolina Negrei

Background: Neuroenhancement in sports, through pharmacological and non-pharmacological methods, is a complex and highly debated topic with no definitive regulatory framework established by the World Anti-Doping Agency (WADA). The hypothesis that der...

  • Systematic Review
  • Open Access
1 Citations
2,926 Views
28 Pages

Brain Markers of Resilience to Psychosis in High-Risk Individuals: A Systematic Review and Label-Based Meta-Analysis of Multimodal MRI Studies

  • Guusje Collin,
  • Joshua E. Goldenberg,
  • Xiao Chang,
  • Zhenghan Qi,
  • Susan Whitfield-Gabrieli,
  • Wiepke Cahn,
  • Jijun Wang,
  • William S. Stone,
  • Matcheri S. Keshavan and
  • Martha E. Shenton

Background/Objectives: Most individuals who have a familial or clinical risk of developing psychosis remain free from psychopathology. Identifying neural markers of resilience in these at-risk individuals may help clarify underlying mechanisms and yi...

  • Article
  • Open Access
1 Citations
1,756 Views
17 Pages

Altered Hemispheric Asymmetry of Functional Hierarchy in Schizophrenia

  • Yi Zhen,
  • Hongwei Zheng,
  • Yi Zheng,
  • Zhiming Zheng,
  • Yaqian Yang and
  • Shaoting Tang

Background/Objectives: Schizophrenia is a severe psychiatric disorder characterized by deficits in perception and advanced cognitive functions. Prior studies have reported abnormal lateralization in cortical morphology and functional connectivity in...

  • Article
  • Open Access
1 Citations
1,692 Views
15 Pages

Differences in Gaze Behavior Between Male and Female Elite Handball Goalkeepers During Penalty Throws

  • Wojciech Jedziniak,
  • Krystian Panek,
  • Piotr Lesiakowski,
  • Beata Florkiewicz and
  • Teresa Zwierko

Background: Recent research suggests that an athlete’s gaze behavior plays a significant role in expert sport performance. However, there is a lack of studies investigating sex differences in gaze behavior during technical and tactical actions....

  • Article
  • Open Access
1 Citations
2,300 Views
12 Pages

Presence of Psychotic Spectrum Symptoms Before Age 12 in Schizophrenia Patients: A Retrospective Study on Clinical Implications for Early Detection and Intervention

  • Pietro Carmellini,
  • Alessandro Cuomo,
  • Annarita Vignapiano,
  • Francesco Monaco,
  • Simone Pardossi,
  • Bernardo Firenzuoli and
  • Andrea Fagiolini

Background/Objectives: Schizophrenia is a severe psychiatric disorder, with onset typically occurring in late adolescence or early adulthood. Early identification of psychotic symptoms, especially those occurring before age 12, has been linked to bet...

  • Article
  • Open Access
2 Citations
1,831 Views
19 Pages

Olfactory Testing and Gray Matter Volume: A Combined Approach to Predict the Conversion to Alzheimer

  • Claudia Casadio,
  • Daniela Ballotta,
  • Francesco Ricci,
  • Vanessa Zanelli,
  • Omar Carpentiero,
  • Maria Giulia Corni,
  • Elisa Bardi,
  • Nicola Filippini,
  • Fausta Lui and
  • Paolo Frigio Nichelli
  • + 2 authors

Background/Objectives: Olfactory decline is common in normal aging and frequent in neurodegenerative diseases such as Alzheimer’s disease (AD). Therefore, it has been suggested as a marker for the Mild Cognitive Impairment (MCI) progression to...

  • Review
  • Open Access
4 Citations
5,761 Views
20 Pages

Current Applications of Single-Cell RNA Sequencing in Glioblastoma: A Scoping Review

  • Edgar G. Ordóñez-Rubiano,
  • Nicolás Rincón-Arias,
  • William J. Shelton,
  • Andres F. Salazar,
  • María Alejandra Sierra,
  • Raphael Bertani,
  • Diego F. Gómez-Amarillo,
  • Fernando Hakim,
  • Matías Baldoncini and
  • César Payán-Gómez
  • + 3 authors

Background and Objective: The discovery of novel molecular biomarkers via next-generation sequencing technologies has revolutionized how glioblastomas (GBMs) are classified nowadays. This has resulted in more precise diagnostic, prognostic, and thera...

  • Review
  • Open Access
1,101 Views
14 Pages

Background/Objectives: Pain memory refers to the ability to encode, store, and recall information related to a specific pain event. Reviewing its common features is crucial, as it provides researchers with a foundational guide for designing studies t...

  • Article
  • Open Access
1 Citations
5,061 Views
19 Pages

Background: The beat-by-beat fluctuation of heart rate (HR) in its temporal sequence (HR dynamics) provides information on HR regulation by the autonomic nervous system (ANS) and its dysregulation in pathological states. Commonly, linear analyses of...

  • Review
  • Open Access
6 Citations
5,707 Views
19 Pages

Neurobiological Relationships Between Neurodevelopmental Disorders and Mood Disorders

  • Amanda Gollo Bertollo,
  • Camila Ferreira Puntel,
  • Brunna Varela da Silva,
  • Marcio Martins,
  • Margarete Dulce Bagatini and
  • Zuleide Maria Ignácio

According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), neurodevelopmental disorders (NDDs) are a group of conditions that arise early in development and are characterized by deficits in personal, social, academic, or occupati...

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Brain Sci. - ISSN 2076-3425