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Brain Sciences, Volume 14, Issue 9

2024 September - 102 articles

Cover Story: Mitochondrial dysfunction has been implicated in various neurodegenerative disorders, including Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis, and Huntington’s diseases. Understanding the impact of mitochondrial biology on these conditions can provide valuable insights for developing targeted cell therapies. This mini-review refocuses on the mitochondria and emphasizes the potential of therapies leveraging mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, stem cell-derived secretions, and extracellular vesicles. Mesenchymal stem cell-mediated mitochondrial transfer is highlighted for the restoration of mitochondrial health in cells with dysfunctional mitochondria. Additionally, attention is paid to gene-editing techniques such as mito-CRISPR, mitoTALENs, mito-ZNFs, and DdCBEs to ensure the safety and efficacy of stem cell treatments. View this paper
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Articles (102)

  • Review
  • Open Access
22 Citations
6,227 Views
17 Pages

The Kynurenine Pathway, Aryl Hydrocarbon Receptor, and Alzheimer’s Disease

  • Enoc Mariano Cortés Malagón,
  • Adolfo López Ornelas,
  • Irlanda Olvera Gómez and
  • José Bonilla Delgado

23 September 2024

Alzheimer’s disease (AD) is the leading cause of dementia, mainly affecting elderly individuals. AD is characterized by β-amyloid plaques, abnormal tau tangles, neuronal loss, and metabolic disruptions. Recent studies have revealed the inv...

(This article belongs to the Section Neurodegenerative Diseases)
  • Article
  • Open Access
9 Citations
7,368 Views
18 Pages

Repetitive Transcranial Magnetic Stimulation for the Treatment of Depression in a Real-World Setting: Findings from a Cohort Study

  • Tiziano Prodi,
  • Gabriele Pezzullo,
  • Kevin La Monica,
  • Alberto Priori and ,
  • Matteo Vismara,
  • Bernardo Dell’Osso and
  • Beatrice Benatti
  • + 2 authors+ 0 author

22 September 2024

Background/Objectives: In the past two decades, significant advancements in neuromodulation techniques have occurred, such as transcranial magnetic stimulation (TMS) for treatment-resistant depression (TRD). According to the assumption that repeated...

(This article belongs to the Special Issue Brain Stimulation for Psychiatric Disorders: Emerging Evidence and New Perspectives)
  • Review
  • Open Access
20 Citations
6,837 Views
30 Pages

Calcitonin Gene-Related Peptide Monoclonal Antibodies: Key Lessons from Real-World Evidence

  • Bianca Orlando,
  • Gabriella Egeo,
  • Cinzia Aurilia,
  • Giulia Fiorentini and
  • Piero Barbanti

22 September 2024

Background: The advent of monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway has transformed the management of migraine, offering newfound optimism for clinicians and individuals with episodic migraine (EM) and...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Review
  • Open Access
3 Citations
7,144 Views
14 Pages

22 September 2024

Background: Musculoskeletal pain is a leading cause of medical visits, posing significant challenges both socially and economically, encouraging the scientific community to continue researching and exploring the most effective methods to address the...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
9 Citations
3,915 Views
18 Pages

Lenition in L2 Spanish: The Impact of Study Abroad on Phonological Acquisition

  • Ratree Wayland,
  • Rachel Meyer,
  • Sophia Vellozzi and
  • Kevin Tang

21 September 2024

Objective: This study investigated the degrees of lenition, or consonantal weakening, in the production of Spanish stop consonants by native English speakers during a study abroad (SA) program. Lenition is a key phonological process in Spanish, where...

(This article belongs to the Section Neurolinguistics)
  • Article
  • Open Access
18 Citations
7,089 Views
14 Pages

Transcutaneous Auricular Vagus Nerve Stimulation Modulating the Brain Topological Architecture of Functional Network in Major Depressive Disorder: An fMRI Study

  • Zhi-Peng Guo,
  • Dan Liao,
  • Lei Chen,
  • Cong Wang and ,
  • Miao Qu,
  • Xue-Yu Lv,
  • Ji-Liang Fang and
  • Chun-Hong Liu
  • + 3 authors+ 0 author

21 September 2024

Background: Transcutaneous auricular vagus nerve stimulation (taVNS) is effective in regulating mood and high-level cognition in patients with major depressive disorder (MDD). This study aimed to investigate the efficacy of taVNS treatment in patient...

(This article belongs to the Special Issue Brain Stimulation for Psychiatric Disorders: Emerging Evidence and New Perspectives)
  • Article
  • Open Access
1,684 Views
12 Pages

Neuronal Mechanisms of Reading Informational Texts in People with Different Levels of Mental Resilience

  • Małgorzata Chojak,
  • Anna Gawron,
  • Marta Czechowska-Bieluga,
  • Andrzej Różański and ,
  • Ewa Sarzyńska-Mazurek and
  • Anna Stachyra-Sokulska
  • + 1 author+ 0 author

21 September 2024

The aim of this study was to verify whether the level of mental resilience would differentiate reading comprehension performance when using different information carriers. More than 150 people filled out a test regarding the level of resilience. They...

(This article belongs to the Topic Risk and Protective Factors in Social Interactions: Behavioral and Neural Evidence)
  • Article
  • Open Access
1 Citations
4,366 Views
18 Pages

21 September 2024

Objectives: The main purpose of the current study was to examine the effects of social information processing, self-regulation, and metacognition variables on ToM using path analysis. Methods: For this purpose, path analysis was conducted for the mod...

(This article belongs to the Section Educational Neuroscience)
  • Review
  • Open Access
2 Citations
11,400 Views
29 Pages

Biostasis: A Roadmap for Research in Preservation and Potential Revival of Humans

  • Andrew T. McKenzie,
  • Brian Wowk,
  • Anton Arkhipov,
  • Borys Wróbel and ,
  • Nathan Cheng and
  • Emil F. Kendziorra
  • + 1 author+ 0 author

21 September 2024

Human biostasis, the preservation of a human when all other contemporary options for extension of quality life are exhausted, offers the speculative potential for survival via continuation of life in the future. While provably reversible preservation...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
12 Citations
5,852 Views
14 Pages

Effectiveness of Two Models of Telerehabilitation in Improving Recovery from Subacute Upper Limb Disability after Stroke: Robotic vs. Non-Robotic

  • Arianna Pavan,
  • Alessio Fasano,
  • Stefania Lattanzi,
  • Laura Cortellini and ,
  • Valeria Cipollini,
  • Sabina Insalaco,
  • Maria Cristina Mauro,
  • Marco Germanotta and
  • Irene Giovanna Aprile
  • + 4 authors+ 0 author

21 September 2024

Background/Objectives: Finding innovative digital solutions is fundamental to ensure prompt and continuous care for patients with chronic neurological disorders, whose demand for rehabilitation also in home-based settings is steadily increasing. The...

(This article belongs to the Special Issue Collection Series: Neurorehabilitation Insights in 2024)
  • Article
  • Open Access
5 Citations
12,901 Views
24 Pages

20 September 2024

Background/Objectives: With the rapid expansion of the global sports market, the significance of sports sponsorship has attracted growing attention. However, during the golden age of the sports industry’s development in China, international spo...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Review
  • Open Access
12 Citations
5,438 Views
24 Pages

Utility of Quantitative EEG in Neurological Emergencies and ICU Clinical Practice

  • Misericordia Veciana de las Heras,
  • Jacint Sala-Padro,
  • Jordi Pedro-Perez,
  • Beliu García-Parra and ,
  • Guillermo Hernández-Pérez and
  • Merce Falip
  • + 1 author+ 0 author

20 September 2024

The electroencephalogram (EEG) is a cornerstone tool for the diagnosis, management, and prognosis of selected patient populations. EEGs offer significant advantages such as high temporal resolution, real-time cortical function assessment, and bedside...

(This article belongs to the Special Issue Diagnosis and Prediction of Neurological Diseases: Application of EEG-Based Technology)
  • Article
  • Open Access
4 Citations
3,105 Views
10 Pages

Prevalence and Awareness of Medication Overuse Headache among Undergraduate Students at the University of Belgrade

  • Aleksandra Radojičić,
  • Ana Milićević,
  • Mirjana Ždraljević,
  • Marta Jeremić and ,
  • Dajana Orlović and
  • Milija Mijajlović
  • + 1 author+ 0 author

19 September 2024

Background: Medication overuse headache (MOH) is a prevalent and potentially preventable secondary headache disorder linked to the excessive use of medications intended for primary headache management, particularly migraine. Aim: The aim of our study...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Review
  • Open Access
2 Citations
6,697 Views
16 Pages

19 September 2024

Background: This scoping review had as a primary goal a review of the literature and the an analysis of the possible effectiveness of the LSVT LOUD approach in children with voice and speech deficits. Methods: A search was conducted in the Scopus and...

(This article belongs to the Special Issue Recent Advances in Assessment and Rehabilitation of Individuals with Communication and Language Disorders)
  • Review
  • Open Access
3 Citations
5,284 Views
23 Pages

19 September 2024

Exposure to physical and psychological stress modulates pain transmission in a dual manner. Stress-induced analgesia (SIA) refers to the reduction in pain sensitivity that can occur in response to acute stress. On the contrary, chronic stress exposur...

(This article belongs to the Special Issue Stress, Resilience and Susceptibility)
  • Article
  • Open Access
2 Citations
2,124 Views
14 Pages

Abnormal Dynamic Reconfiguration of Multilayer Temporal Networks in Patients with Bipolar Disorder

  • Luyao Lai,
  • Dandan Li,
  • Yating Zhang,
  • Jianchao Hao and ,
  • Xuedong Wang,
  • Xiaohong Cui,
  • Jie Xiang and
  • Bin Wang
  • + 3 authors+ 0 author

19 September 2024

Background: Multilayer networks have been used to identify abnormal dynamic reconfiguration in bipolar disorder (BD). However, these studies ignore the differences in information interactions between adjacent layers when constructing multilayer netwo...

(This article belongs to the Section Neuropsychiatry)
  • Article
  • Open Access
4 Citations
4,140 Views
10 Pages

Clinical and Anatomical Characteristics of Perforator Aneurysms of the Posterior Cerebral Artery: A Single-Center Experience

  • Anahita Malvea,
  • Shigeta Miyake,
  • Ronit Agid,
  • Hugo Andrade Barazarte and ,
  • Richard Farb,
  • Timo Krings,
  • Pascal John Roger Mosimann,
  • Patrick Joseph Nicholson,
  • Ivan Radovanovic and
  • Eef J. Hendriks
  • + 8 authors+ 3 authors

19 September 2024

Introduction: Posterior cerebral artery (PCA) aneurysms represent up to 1% of all cerebral aneurysms. P1-P2 perforator aneurysms are thought to be even less prevalent and often require complex treatment strategies due to their anatomical and morpholo...

(This article belongs to the Special Issue The Latest Exploration of Cerebrovascular Diseases: From Preclinical Research to Treatment)
  • Correction
  • Open Access
1,501 Views
4 Pages

Correction: Amin et al. Hippocampal and Cerebellar Changes in Acute Restraint Stress and the Impact of Pretreatment with Ceftriaxone. Brain Sci. 2020, 10, 193

  • Shaimaa N. Amin,
  • Sherif S. Hassan,
  • Ahmed S. Khashaba,
  • Magdy F. Youakim and ,
  • Noha S. Abdel Latif,
  • Laila A. Rashed and
  • Hanan D. Yassa
  • + 2 authors+ 0 author

18 September 2024

In the original publication [...]

  • Article
  • Open Access
4 Citations
8,655 Views
16 Pages

Brain Evaluation by Dual PET/CT with [18F] FDOPA and [18F] FDG in Differential Diagnosis of Parkinsonian Syndromes

  • Fabio Andrés Sinisterra Solís,
  • Francisco Rubén Romero Castellanos,
  • Emilly Alejandra Cortés Mancera,
  • Ana L. Calderón Ávila and ,
  • Sofía Denisse González Rueda,
  • Juan Salvador Rosales García,
  • Nora Estela Kerik Rotenberg,
  • Dioselina Panamá Tristán Samaniego and
  • Andrés Mauricio Bonilla Navarrete
  • + 4 authors+ 0 author

18 September 2024

Parkinsonian syndromes are considered clinicopathological conditions that are challenging to diagnose. Molecular imaging with [18F]-FDOPA and [18F]-FDG contributes to a more accurate clinical diagnosis by evaluating presynaptic dopaminergic pathways...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Article
  • Open Access
5 Citations
3,459 Views
14 Pages

Exploring Sleep Architecture in Polish Patients with Multiple Sclerosis: A Polysomnography Study

  • Michalina Rzepka,
  • Tomasz Chmiela,
  • Weronika Galus,
  • Anetta Lasek-Bal and
  • Ewa Krzystanek

18 September 2024

Background: Sleep disturbances are a prevalent phenomenon in patients with multiple sclerosis (PwMS). The present study employs polysomnography (PSG) to quantify sleep efficiency and architecture in PwMS, aiming to elucidate the relationships between...

(This article belongs to the Section Sleep and Circadian Neuroscience)
  • Article
  • Open Access
1 Citations
4,250 Views
20 Pages

Real-Time fMRI Neurofeedback Training of Selective Attention in Older Adults

  • Tian Lin,
  • Mohit Rana,
  • Peiwei Liu,
  • Rebecca Polk and ,
  • Amber Heemskerk,
  • Steven M. Weisberg,
  • Dawn Bowers,
  • Ranganatha Sitaram and
  • Natalie C. Ebner
  • + 4 authors+ 0 author

18 September 2024

Background: Selective attention declines with age, due to age-related functional changes in dorsal anterior cingulate cortex (dACC). Real-time functional magnetic resonance imaging (rtfMRI) neurofeedback has been used in young adults to train volitio...

(This article belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
  • Article
  • Open Access
8 Citations
3,507 Views
15 Pages

18 September 2024

Background/Objectives: Problematic online gaming and gambling tend to co-occur. The exact mechanisms underlying this phenomenon and the potential effects of gender differences remain unknown. This study aimed to identify the early clustering patterns...

(This article belongs to the Section Neuropsychiatry)
  • Article
  • Open Access
4,168 Views
16 Pages

Effectiveness of Transcranial Direct Current Stimulation (tDCS) during a Virtual Reality Task in Women with Fibromyalgia—A Randomized Clinical Study

  • Thaís Nogueira da Silva,
  • Vivian Finotti Ribeiro,
  • Margot Carol Condori Apaza,
  • Lívia Gallerani Romana and ,
  • Íbis Ariana Peña de Moraes,
  • Eduardo Dati Dias,
  • Suely Steinschreiber Roizenblatt,
  • Juliana Perez Martinez,
  • Fernando Henrique Magalhães and
  • Carlos Bandeira de Mello Monteiro
  • + 9 authors+ 4 authors

18 September 2024

Background/Objectives: Fibromyalgia (FM) is a chronic condition characterized by widespread musculoskeletal pain, fatigue, and impaired motor performance. This study aimed to investigate the effects of transcranial direct current stimulation (tDCS) d...

(This article belongs to the Special Issue Insight in the Application of Rehabilitation Devices in Neurological Disease)
  • Article
  • Open Access
5 Citations
2,673 Views
23 Pages

Investigation of Deficits in Auditory Emotional Content Recognition by Adult Cochlear Implant Users through the Study of Electroencephalographic Gamma and Alpha Asymmetry and Alexithymia Assessment

  • Giulia Cartocci,
  • Bianca Maria Serena Inguscio,
  • Andrea Giorgi,
  • Dario Rossi and ,
  • Walter Di Nardo,
  • Tiziana Di Cesare,
  • Carlo Antonio Leone,
  • Rosa Grassia,
  • Francesco Galletti and
  • Fabio Babiloni
  • + 9 authors+ 4 authors

17 September 2024

Background/Objectives: Given the importance of emotion recognition for communication purposes, and the impairment for such skill in CI users despite impressive language performances, the aim of the present study was to investigate the neural correlat...

(This article belongs to the Special Issue Recent Advances in Hearing Impairment)
  • Article
  • Open Access
2 Citations
4,217 Views
13 Pages

17 September 2024

Background: This report aims to supplement the existing knowledge on the inferior oblique muscle. In particular, this study presents detailed anatomical and histological data concerning the muscle’s entry point (or entry zone) of the nerve to t...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
7 Citations
2,430 Views
12 Pages

Neonatal Markers of Prematurity as Predictors of Permanent Childhood Hearing Loss and Neurodevelopmental Impairment in Children Admitted to the Neonatal Intensive Care Unit

  • Hayma Moosan,
  • Derek J. Hoare,
  • Dulip Jayasinghe,
  • Karen R. Willis and ,
  • Katherine Martin and
  • Sally K. Thornton
  • + 1 author+ 0 author

17 September 2024

Need for admission to the neonatal intensive care unit (NICU) confers an increased risk of hearing loss in the newborn and of later neurodevelopmental impairment. In this retrospective longitudinal case-controlled study, we assess how the degree of p...

(This article belongs to the Special Issue Recent Advances in Hearing Impairment)
  • Article
  • Open Access
3 Citations
6,459 Views
25 Pages

16 September 2024

Compelling evidence supports the foundational importance of early self-regulation (SR). It also supports parents in the home environment as having the foremost influence on early development. Yet, prevailing approaches to support early SR growth have...

(This article belongs to the Special Issue Effects of Cognitive Training on Executive Function and Cognition)
  • Article
  • Open Access
5 Citations
3,471 Views
22 Pages

16 September 2024

Previous research has established that bilinguals automatically activate lexical items in both of their languages in a nonselectivemanner, even when processing linguistic information in the second language (L2) alone. However, whether this co-activat...

(This article belongs to the Section Neurolinguistics)
  • Article
  • Open Access
3 Citations
2,029 Views
12 Pages

The Systemic Inflammation Response Index Efficiently Discriminates between the Failure Patterns of Patients with Isocitrate Dehydrogenase Wild-Type Glioblastoma Following Radiochemotherapy with FLAIR-Based Gross Tumor Volume Delineation

  • Sukran Senyurek,
  • Murat Serhat Aygun,
  • Nulifer Kilic Durankus,
  • Eyub Yasar Akdemir and ,
  • Duygu Sezen,
  • Erkan Topkan,
  • Yasemin Bolukbasi and
  • Ugur Selek
  • + 3 authors+ 0 author

15 September 2024

Background/Objectives: The objective of this study was to assess the connection between the systemic inflammation response index (SIRI) values and failure patterns of patients with IDH wild-type glioblastoma (GB) who underwent radiotherapy (RT) with...

(This article belongs to the Special Issue Brain Tumors: From Molecular Basis to Therapy)
  • Article
  • Open Access
3 Citations
2,701 Views
17 Pages

Increased Risk for Clinically Significant Sleep Disturbances in Mild Traumatic Brain Injury: An Approach to Leveraging the Federal Interagency Traumatic Brain Injury Research Database

  • Maya E. O’Neil,
  • Danielle Krushnic,
  • William C. Walker,
  • David Cameron and ,
  • William Baker-Robinson,
  • Sara Hannon,
  • Kate Clauss,
  • Tamara P. Cheney,
  • Lawrence J. Cook and
  • Aaron M. Martin
  • + 8 authors+ 3 authors

14 September 2024

Study Objectives: The Federal Interagency Traumatic Brain Injury Research (FITBIR) Informatics System contains individual-patient-level traumatic brain injury (TBI) data, which when combined, allows for the examination of rates and outcomes for key s...

(This article belongs to the Section Sleep and Circadian Neuroscience)
  • Article
  • Open Access
3 Citations
2,008 Views
12 Pages

Contrasting Effects of Oxytocin on MK801-Induced Social and Non-Social Behavior Impairment and Hyperactivity in a Genetic Rat Model of Schizophrenia-Linked Features

  • Daniel Sampedro-Viana,
  • Toni Cañete,
  • Paula Ancil-Gascón,
  • Sonia Cisci and ,
  • Adolf Tobeña and
  • Alberto Fernández-Teruel
  • + 1 author+ 0 author

13 September 2024

Social withdrawal in rodents is a measure of asociality, an important negative symptom of schizophrenia. The Roman high- (RHA) and low-avoidance (RLA) rat strains have been reported to exhibit differential profiles in schizophrenia-relevant behaviora...

(This article belongs to the Special Issue Exploring Negative Symptoms of Schizophrenia: Where Do We Stand?)
  • Article
  • Open Access
2,614 Views
19 Pages

Does Cognitive Load Affect Measures of Consciousness?

  • André Sevenius Nilsen,
  • Johan Frederik Storm and
  • Bjørn Erik Juel

13 September 2024

Background: Developing and testing methods for reliably measuring the state of consciousness of individuals is important for both basic research and clinical purposes. In recent years, several promising measures of consciousness, grounded in theoreti...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
2 Citations
6,205 Views
19 Pages

13 September 2024

This research aimed to investigate the effectiveness of the Eye Movement Desensitization and Reprocessing (EMDR) method on chronic subjective tinnitus. The research was planned as an observational study. The study group comprises individuals who appl...

(This article belongs to the Special Issue Advances in Tinnitus and Hearing Disorders)
  • Article
  • Open Access
7 Citations
2,422 Views
11 Pages

Sensor-Based Balance Training with Exergaming Feedback in Subjects with Chronic Stroke: A Pilot Randomized Controlled Trial

  • Alex Martino Cinnera,
  • Irene Ciancarelli,
  • Serena Marrano,
  • Massimiliano Palagiano and ,
  • Elisa Federici,
  • Alessio Bisirri,
  • Marco Iosa,
  • Stefano Paolucci,
  • Giacomo Koch and
  • Giovanni Morone
  • + 5 authors+ 0 author

13 September 2024

Background: As one of the leading causes of disability in the world, stroke can determine a reduction of balance performance with a negative impact on daily activity and social life. In this study, we aimed to evaluate the effects of sensor-based bal...

(This article belongs to the Special Issue Stroke and Acute Stroke Care: Looking Ahead)
  • Article
  • Open Access
1 Citations
1,906 Views
11 Pages

Comparison between Motor Performance of People with Multiple Sclerosis during a Virtual Reality Task Practiced on Concrete and Abstract Devices: A Cross-Sectional Randomized Study

  • Camila Miliani Capelini,
  • Giulianna Mendes Ferrero,
  • Ana Maria Canzonieri,
  • Roger Pereira Silva and ,
  • Mauricio Ossamu Bando,
  • Renata Martins Rosa,
  • Cintia Ramari Ferreira,
  • Talita Dias da Silva,
  • Alessandro Hervaldo Nicolai Ré and
  • Carlos Bandeira de Mello Monteiro
  • + 8 authors+ 3 authors

12 September 2024

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system with unknown etiology, resulting in various impairments that necessitate continuous rehabilitation to enhance functionality, quality of life, and motor funct...

(This article belongs to the Section Neurodegenerative Diseases)
  • Article
  • Open Access
2,349 Views
15 Pages

Fronto-Central Changes in Multiple Frequency Bands in Active Tactile Width Discrimination Task

  • Tiago Ramos,
  • Júlia Ramos,
  • Carla Pais-Vieira and
  • Miguel Pais-Vieira

11 September 2024

The neural basis of tactile processing in humans has been extensively studied; however, the neurophysiological basis of human width discrimination remains relatively unexplored. In particular, the changes that occur in neural networks underlying acti...

(This article belongs to the Special Issue New Insights into Movement Generation: Sensorimotor Processes)
  • Brief Report
  • Open Access
2 Citations
2,159 Views
7 Pages

Video-Guided Optimization of Stimulation Settings in Patients with Parkinson’s Disease and Deep Brain Stimulation

  • Hannah Jergas,
  • Julia K. Steffen,
  • Charlotte Schedlich-Teufer,
  • Joshua N. Strelow and ,
  • Johanna Kramme,
  • Gereon R. Fink,
  • Veerle Visser-Vandewalle,
  • Michael T. Barbe and
  • Jochen Wirths
  • + 4 authors+ 0 author

11 September 2024

Deep brain stimulation (DBS) for Parkinson’s disease (PD) often necessitates frequent clinic visits for stimulation program optimization, with limited experience in remote patient management. Due to the resource-intensive nature of these proced...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Article
  • Open Access
2,132 Views
15 Pages

The Contribution of Cognitive Control Networks in Word Selection Processing in Parkinson’s Disease: Novel Insights from a Functional Connectivity Study

  • Sonia Di Tella,
  • Matteo De Marco,
  • Isabella Anzuino,
  • Davide Quaranta and ,
  • Francesca Baglio and
  • Maria Caterina Silveri
  • + 1 author+ 0 author

11 September 2024

Parkinson’s disease (PD) patients are impaired in word production when the word has to be selected among competing alternatives requiring higher attentional resources. In PD, word selection processes are correlated with the structural integrity...

(This article belongs to the Special Issue New Challenges in the Study of Cognitive Impairment in Parkinson’s Disease)
  • Article
  • Open Access
2,139 Views
13 Pages

Ultrasound-Induced Release Profile of Nimodipine from Drug-Loaded Block Copolymers after Singular vs. Repeated Sonication: In Vitro Analysis in Artificial Cerebrospinal Fluid

  • Katja Döring,
  • Swetlana Sperling,
  • Milena Ninkovic,
  • Heinrich Lanfermann and ,
  • Frank Streit,
  • Andreas Fischer,
  • Veit Rohde and
  • Vesna Malinova
  • + 3 authors+ 0 author

10 September 2024

Objective: Nimodipine still represents a unique selling point in the prevention of delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH). Its intrathecal effect is limited by a low oral bioavailability, leading to the de...

(This article belongs to the Special Issue The Latest Exploration of Cerebrovascular Diseases: From Preclinical Research to Treatment)
  • Article
  • Open Access
1 Citations
2,370 Views
12 Pages

10 September 2024

The aim of this study is to present the outcomes of cerebral aneurysm treatment with the DERIVO® mini Embolisation Device (DMD), which is compatible with microcatheters with 0.021-inch inner diameters. Consecutive patients treated with DMD were i...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
6 Citations
4,875 Views
13 Pages

9 September 2024

The present study analyzed the association between anxiety, repetitive behavior and parental stress in individuals with autism from Spain (n = 60, mean age = 8.52, SD = 4.41) and Colombia (n = 58, mean age = 10.29, SD = 4.98). Similarly, differences...

(This article belongs to the Special Issue Exploring the Mental Health of People with Autism)
  • Systematic Review
  • Open Access
16 Citations
4,842 Views
21 Pages

Apolipoprotein E and Alzheimer’s Disease in Italian Population: Systematic Review and Meta-Analysis

  • Diana Marisol Abrego-Guandique,
  • Giorgia Francesca Saraceno,
  • Roberto Cannataro,
  • Marilyn Manzzo de Burnside and ,
  • Maria Cristina Caroleo and
  • Erika Cione
  • + 1 author+ 0 author

7 September 2024

Objective: This meta-analysis with a systematic review was undertaken to assess the association between APOE allelic genotypes and the risk of Alzheimer’s disease (AD) in the Italian population. Methods: The Web of Science, PubMed, and Scopus d...

(This article belongs to the Section Neurodegenerative Diseases)
  • Review
  • Open Access
2,807 Views
14 Pages

7 September 2024

In this narrative review, we explore the latest evidence on semantic interventions for older adults, including both prevention and rehabilitation/remediation efforts, discussing them particularly in the context of dementia. Cognitive interventions va...

(This article belongs to the Special Issue Advances in Memory and Cognitive Decline Associated with Aging and Alzheimer's Disease)
  • Case Report
  • Open Access
5 Citations
2,450 Views
20 Pages

Bidirectional and Cross-Hemispheric Modulations of Face-Selective Neural Activity Induced by Electrical Stimulation within the Human Cortical Face Network

  • Luna Angelini,
  • Corentin Jacques,
  • Louis Maillard,
  • Sophie Colnat-Coulbois and ,
  • Bruno Rossion and
  • Jacques Jonas
  • + 1 author+ 0 author

6 September 2024

A major scientific objective of cognitive neuroscience is to define cortico-cortical functional connections supporting cognitive functions. Here, we use an original approach combining frequency-tagging and direct electrical stimulation (DES) to test...

(This article belongs to the Special Issue Recent Advances in Brain Lateralization)
  • Article
  • Open Access
5 Citations
2,387 Views
14 Pages

Functional MRI Assessment of Brain Activity Patterns Associated with Reading in Medulloblastoma Survivors

  • Josue L. Dalboni da Rocha,
  • Ping Zou Stinnett,
  • Matthew A. Scoggins,
  • Samuel S. McAfee and ,
  • Heather M. Conklin,
  • Amar Gajjar and
  • Ranganatha Sitaram
  • + 2 authors+ 0 author

6 September 2024

Medulloblastoma, a malignant brain tumor primarily affecting children, poses significant challenges to patients and clinicians due to its complex treatment and potential long-term cognitive consequences. While recent advancements in treatment have si...

(This article belongs to the Section Neuro-oncology)
  • Case Report
  • Open Access
1,648 Views
12 Pages

6 September 2024

Members of three generations of a Norwegian family (N = 9) with a rare demyelinating disease were studied. Neuropsychological testing was performed using the Mini Mental Status Examination (MMSE), Wechsler Intelligence Scale-III (WAIS-III), and Hopki...

(This article belongs to the Section Neurodegenerative Diseases)
  • Article
  • Open Access
2 Citations
2,431 Views
16 Pages

Effect of Chronic Tibolone Administration on Memory and Choline Acetyltransferase and Tryptophan Hydroxylase Content in Aging Mice

  • Tzayaka Castillo-Mendieta,
  • Guadalupe Bautista-Poblet,
  • Angélica Coyoy-Salgado,
  • Emily L. Castillo-García and ,
  • Rodolfo Pinto-Almazán,
  • Claudia Erika Fuentes-Venado,
  • Teresa Neri-Gómez and
  • Christian Guerra-Araiza
  • + 3 authors+ 0 author

6 September 2024

Gonadal steroids exert different effects on the central nervous system (CNS), such as preserving neuronal function and promoting neuronal survival. Estradiol, progesterone, and testosterone reduce neuronal loss in the CNS in animal models of neurodeg...

(This article belongs to the Section Neurodegenerative Diseases)
  • Review
  • Open Access
24 Citations
13,524 Views
16 Pages

6 September 2024

Extensive research has shed light on the cellular and functional underpinnings of higher cognition as influenced by the prefrontal cortex. Neurotransmitters act as key regulatory molecules within the PFC to assist with synchronizing cognitive state a...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
10 Citations
5,236 Views
22 Pages

Tai Chi Practice Buffers Aging Effects in Functional Brain Connectivity

  • Jonathan Cerna,
  • Prakhar Gupta,
  • Maxine He,
  • Liran Ziegelman and ,
  • Yang Hu and
  • Manuel E. Hernandez
  • + 1 author+ 0 author

6 September 2024

Tai Chi (TC) practice has been shown to improve both cognitive and physical function in older adults. However, the neural mechanisms underlying the benefits of TC remain unclear. Our primary aims are to explore whether distinct age-related and TC-pra...

(This article belongs to the Special Issue Advances of AI in Neuroimaging)

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Brain Sci. - ISSN 2076-3425