Skip to Content

Pathogens, Volume 14, Issue 7

2025 July - 113 articles

Cover Story: The present study utilizes herpes simplex virus type 1 (HSV-1), a rare but serious respiratory infection that causes pneumonia in the elderly, to demonstrate that aging exacerbates lung infection and disease in mice. Compared to young and adult mice, aged mice exhibited (i) impaired expression of TLR3, a marker that plays a crucial role in antiviral response, on airway epithelial cells, dendritic cells, and macrophages; (ii) decreased frequencies of activated dendritic cells expressing MHC-I, MHC-II, and CD80/86; (iii) decreased frequencies of antiviral CD4+ and CD8+ T cells expressing cytotoxic markers (GzmB and CD107) and producing IFN-γ; and (iv) reduced anti-inflammatory cytokines in the lungs. These findings highlight an age-associated decline of innate and adaptive immune responses to respiratory viral infections. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (113)

  • Article
  • Open Access
3 Citations
2,314 Views
12 Pages

Detection and Molecular Characterization of Rift Valley Fever Virus in Apparently Healthy Cattle in Uganda

  • Eugene Arinaitwe,
  • Kaitlyn Waters,
  • Bonto Faburay,
  • Gladys K. Nakanjako and ,
  • David Kalenzi Atuhaire,
  • Mathias Afayoa,
  • Frank Norbert Mwiine and
  • Joseph Erume
  • + 3 authors+ 0 author

Rift Valley fever (RVF) is a zoonotic disease caused by the Rift Valley fever virus (RVFV), affecting humans, livestock, and wild ruminants. This study aimed to characterize and assess the genetic diversity of RVFV strains circulating among livestock...

(This article belongs to the Section Emerging Pathogens)
  • Article
  • Open Access
4 Citations
1,392 Views
11 Pages

A Look Under the Carpet of a Successful Eradication Campaign Against Small Ruminant Lentiviruses

  • Fadri Vincenz,
  • Maksym Samoilenko,
  • Carlos Eduardo Abril,
  • Patrik Zanolari and ,
  • Giuseppe Bertoni and
  • Beat Thomann
  • + 1 author+ 0 author

Small ruminant lentiviruses (SRLVs) are widespread and have a long co-evolutionary history with their hosts, namely sheep and goats. These viruses induce insidious pathologies, causing significant financial losses and animal welfare issues for the af...

(This article belongs to the Special Issue Emergence and Re-Emergence of Animal Viral Diseases)
  • Article
  • Open Access
2 Citations
1,801 Views
18 Pages

Vector-Borne Agents in Species of Silky Anteater (Cyclopes Gray, 1821) from South America

  • Pedro Henrique Cotrin Rodrigues,
  • João Paulo Soares Alves,
  • Flávia Regina Miranda,
  • Cesar Rojano and
  • Júlia Angélica Gonçalves Silveira

Cyclopes, the smallest of all known anteaters, has an insectivorous diet and is arboreal, rarely descending to the ground. There are scarce reports on diseases and pathogenic agents affecting this taxon. Hemopathogens are pathogenic agents that inhab...

(This article belongs to the Special Issue Exploring the Biodiversity of Parasites in Humans, Wild and Domestic Animals)
  • Systematic Review
  • Open Access
14 Citations
12,788 Views
17 Pages

Efficacy of GS-441524 for Feline Infectious Peritonitis: A Systematic Review (2018–2024)

  • Emma Gokalsing,
  • Joana Ferrolho,
  • Mark S. Gibson,
  • Hugo Vilhena and
  • Sofia Anastácio

Feline infectious peritonitis (FIP) is a severe viral disease with a very high fatality rate. GS-441524 is an adenosine analogue that acts as an antiviral and has shown promise in FIP treatment. However, its commercialization in some regions is not y...

  • Article
  • Open Access
4 Citations
1,672 Views
27 Pages

Distinct Virologic Properties of African and Epidemic Zika Virus Strains: The Role of the Envelope Protein in Viral Entry, Immune Activation, and Neuropathogenesis

  • Ashkan Roozitalab,
  • Chenyu Zhang,
  • Jiantao Zhang,
  • Ge Li and ,
  • Chengyu Yang,
  • Wangheng Hou,
  • Qiyi Tang and
  • Richard Y. Zhao
  • + 3 authors+ 0 author

The 2016 Zika virus (ZIKV) epidemic has largely subsided, but a key question remains. How did ZIKV evolve to become a virulent human pathogen compared to the virus of its original discovery? What specific virologic and pathologic changes contributed...

(This article belongs to the Special Issue Advances in Virus-Host Interactions, Viral Pathogenicity and Antiviral Drug Development)
  • Article
  • Open Access
2,552 Views
12 Pages

Coinfections with hepatitis C virus (HCV) or human immunodeficiency virus (HIV) among individuals with chronic hepatitis B (CHB) are associated with worse clinical outcomes but remain understudied due to their low prevalence and the sensitivity of as...

(This article belongs to the Special Issue Viral Hepatitis Among Specific Populations: Epidemiology, Transmission, Treatment, and Prevention)
  • Article
  • Open Access
1 Citations
1,720 Views
17 Pages

A Novel Parvovirus Associated with the Whitefly Bemisia tabaci

  • Fani Gousi,
  • Zineb Belabess,
  • Nathalie Laboureau,
  • Michel Peterschmitt and
  • Mikhail M. Pooggin

The whitefly Bemisia tabaci (Hemiptera: Aleyrodoidea) causes direct feeding damage to crop plants and transmits pathogenic plant viruses, thereby threatening global food security. Although whitefly-infecting RNA viruses are known and proposed as bioc...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
7 Citations
1,959 Views
15 Pages

Expanding the Antiviral Spectrum of Scorpion-Derived Peptides Against Toscana Virus and Schmallenberg Virus

  • Rosa Giugliano,
  • Carla Zannella,
  • Roberta Della Marca,
  • Annalisa Chianese and ,
  • Laura Di Clemente,
  • Alessandra Monti,
  • Nunzianna Doti,
  • Federica Cacioppo,
  • Valentina Iovane and
  • Anna De Filippis
  • + 8 authors+ 3 authors

Toscana virus (TOSV) and Schmallenberg virus (SBV) are arthropod-borne viruses from the Bunyaviricetes class, posing significant human and animal health threats. TOSV, endemic to the Mediterranean region, is a notable human pathogen detected in vario...

(This article belongs to the Special Issue Current Challenges in Veterinary Virology)
  • Article
  • Open Access
4 Citations
1,745 Views
16 Pages

Surveillance of Salmonella Serovars in the Food Chain in Poland: A Five-Year Review (2016–2020)

  • Ewelina Skrzypiec,
  • Magdalena Skarżyńska,
  • Magdalena Zając,
  • Renata Kwit and ,
  • Anna Lalak,
  • Aleksandra Śmiałowska-Węglińska,
  • Emilia Mikos-Wojewoda,
  • Paulina Pasim,
  • Weronika Koza and
  • Dariusz Wasyl
  • + 9 authors+ 4 authors

(1) Background: Understanding the distribution of Salmonella serovars in food, animals, and their environments is crucial for identifying infection sources and monitoring pathogen prevalence in the food chain. This study analysed Salmonella serovars...

  • Article
  • Open Access
4 Citations
2,386 Views
21 Pages

Pneumococcal Infection and Vaccination-Related Knowledge, Attitudes and Practices Among Saudi Residents

  • Wed S. Althobaiti,
  • Abeer D. Alnefaie,
  • Kaifah M. Althaali,
  • Ola M. Alsufyani and ,
  • Yassmin M. Shebany,
  • Ayman A. Atalla,
  • Ibtihal M. Alotaibi,
  • Eman Y. Santali and
  • Sayed F. Abdelwahab
  • + 4 authors+ 0 author

Background and aims: Pneumococcal infections, primarily caused by Streptococcus pneumoniae, pose significant global public health challenges, particularly in vulnerable populations. In Saudi Arabia, the introduction of pneumococcal vaccination has be...

  • Communication
  • Open Access
3 Citations
1,574 Views
11 Pages

First Report of Triple Viral Co-Infection (PPV, PCV2, PCMV) in Wild Boars in the Western Balkans

  • Dimitrije Glišić,
  • Sofija Šolaja,
  • Kukilo Stevan,
  • Vesna Milićević and ,
  • Miloš Vučićević,
  • Jelena Aleksić and
  • Dajana Davitkov
  • + 2 authors+ 0 author

Wild boars are recognized reservoirs of numerous viral pathogens, posing a significant risk to domestic pig populations, particularly in areas with poor biosecurity. This study assessed the prevalence and co-infection patterns of porcine circovirus t...

(This article belongs to the Special Issue Current Challenges in Veterinary Virology)
  • Article
  • Open Access
6 Citations
4,127 Views
15 Pages

Antibacterial Activity of Clove Essential Oil (Syzygium aromaticum) Against Oxacillin-Resistant Staphylococcus pseudintermedius Isolated from Dogs with Otitis Externa

  • Vanessa Danielle de Freitas,
  • Edison Lorran Jerdlicka Coelho,
  • Janaina Marcela Assunção Rosa Moreira,
  • Valéria Dutra and ,
  • Valéria Régia Franco Sousa and
  • Arleana do Bom Parto Ferreira de Almeida
  • + 1 author+ 0 author

Infections caused by oxacillin-resistant Staphylococcus pseudintermedius are increasingly common in veterinary medicine. The indiscriminate use of antibiotics by pet owners worsens this problem, reducing treatment efficacy and creating the need for a...

  • Article
  • Open Access
3 Citations
1,654 Views
18 Pages

From Delta to Omicron—Genetic Epidemiology of SARS-CoV-2 (hCoV-19) in Southern Poland

  • Maria Miklasińska-Majdanik,
  • Emilia Morawiec,
  • Jolanta Bratosiewicz-Wąsik,
  • Karol Serwin and ,
  • Adam Pudełko,
  • Michał Czerwiński,
  • Anna Bednarska-Czerwińska,
  • Miłosz Parczewski and
  • Tomasz J. Wąsik
  • + 4 authors+ 0 author

Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, in December 2019, it has evolved, leading to variants that differ in their transmissibility, severity of disease, and susceptibility to therapy. Ou...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
2 Citations
3,261 Views
14 Pages

Development of a Clostridium Perfringens Challenge Model in Broiler Chickens to Evaluate the Effects of Feed Additives

  • Anna Kollár,
  • Kinga Selymes,
  • Gergely Tóth,
  • Sándor Szekeres and ,
  • Péter Ferenc Dobra,
  • Krisztina Bárdos,
  • László Ózsvári,
  • Zsófia Bata,
  • Viviána Molnár-Nagy and
  • Miklós Tenk
  • + 5 authors+ 0 author

Necrotic enteritis, caused by Clostridium perfringens (C. perfringens) is a disease present worldwide and causes major economic losses. The re-emergence of the disease, in recent years, is mainly due to the ban of the usage of antibiotics as growth p...

  • Review
  • Open Access
1 Citations
2,810 Views
12 Pages

Exophiala Bloodstream Infections in Humans—A Narrative Review

  • Afroditi Ziogou,
  • Alexios Giannakodimos,
  • Ilias Giannakodimos,
  • Stella Baliou and ,
  • Andreas G. Tsantes and
  • Petros Ioannou
  • + 1 author+ 0 author

Background: Exophiala spp. are dematiaceous fungi with opportunistic pathogenic potential and a widespread environmental presence. Clinical cases of Exophiala spp. fungemia are uncommon. Although rarely encountered in the general population, the...

(This article belongs to the Section Fungal Pathogens)
  • Article
  • Open Access
8 Citations
2,543 Views
15 Pages

Study of Class 1, 2, and 3 Integrons, Antibiotic Resistance Patterns, and Biofilm Formation in Clinical Staphylococcus aureus Isolates from Hospital-Acquired Infections

  • Eman E. Hegazy,
  • Wageih Salem ElNaghy,
  • Marwa M. Shalaby,
  • Sarah M. Shoeib and ,
  • Nashwa S. M. Abdeen,
  • Mohamed H. Fouda,
  • Ola A. Elshora,
  • Mohammed H. Elnaggar,
  • Waleed Elrefaey and
  • Maha S. Elnady
  • + 11 authors+ 6 authors

Antibiotic resistance and biofilm formation complicate Staphylococcus aureus infections, raising concerns for global health. Understanding antimicrobial resistance and biofilm formation in these pathogens is essential for effective infection manageme...

  • Systematic Review
  • Open Access
21 Citations
5,837 Views
26 Pages

Hepatitis E Virus (HEV) Infection in the Context of the One Health Approach: A Systematic Review

  • Sophie Deli Tene,
  • Abou Abdallah Malick Diouara,
  • Sarbanding Sané and
  • Seynabou Coundoul

Hepatitis E virus (HEV) is a pathogen that has caused various epidemics and sporadic localized cases. It is considered to be a public health problem worldwide. HEV is a small RNA virus with a significant genetic diversity, a broad host range, and a h...

(This article belongs to the Section Viral Pathogens)
  • Case Report
  • Open Access
2 Citations
3,002 Views
19 Pages

Fatal Paraclostridium sordellii Infection: Post-Mortem Assessment and Review of the Literature

  • Martina Focardi,
  • Simone Faccioli,
  • Beatrice Defraia,
  • Rossella Grifoni and ,
  • Ilenia Bianchi,
  • Fabio Vaiano,
  • Luca Novelli,
  • Nunziata Ciccone,
  • Emanuele Capasso and
  • Gian Maria Rossolini
  • + 7 authors+ 2 authors

Clostridium sordellii, which has recently been reclassified as Paeniclostridium sordellii and subsequently as Paraclostridium sordellii, is a rare human pathogen linked to infections of high morbidity and mortality, often presenting as fulminant toxi...

  • Article
  • Open Access
4 Citations
5,345 Views
13 Pages

Retrospective Review of Children Hospitalized for Epstein–Barr Virus-Related Infectious Mononucleosis

  • Shufeng Tian,
  • Jinjun Zheng,
  • Zhe Zhou,
  • Qingluan Yang and ,
  • Biao Sun,
  • Yuxi Li,
  • Zengrui Lin,
  • Yuchun Long,
  • Song Guan and
  • Jikui Deng
  • + 9 authors+ 4 authors

Objectives: Our objective was to investigate the clinical characteristics, complications, and treatment outcomes of Epstein–Barr virus (EBV)-related infectious mononucleosis (IM) in children and to identify risk factors associated with prolonge...

  • Article
  • Open Access
3 Citations
1,343 Views
15 Pages

Progress in Our Understanding of the Cross-Protection Mechanism of CTV-VT No-SY Isolates Against Homologous SY Isolates

  • Grazia Licciardello,
  • Giuseppe Scuderi,
  • Marcella Russo,
  • Marina Bazzano and ,
  • Giuseppe Paradiso,
  • Moshe Bar-Joseph and
  • Antonino F. Catara
  • + 2 authors+ 0 author

The Citrus tristeza virus (CTV), a member of the Closterovirus genus, is considered a serious threat to citrus trees grafted onto sour orange (SO) rootstock. In the Mediterranean area, the most prevalent CTV strains are VT and T30. The VT strain incl...

  • Article
  • Open Access
4 Citations
2,732 Views
21 Pages

Harnessing Hazara Virus as a Surrogate for Crimean–Congo Hemorrhagic Fever Virus Enables Inactivation Studies at a Low Biosafety Level

  • Judith Olejnik,
  • Kristina Meier,
  • Jarod N. Herrera,
  • Daniel J. DeStasio and ,
  • Dylan J. Deeney,
  • Elizabeth Y. Flores,
  • Mitchell R. White,
  • Adam J. Hume and
  • Elke Mühlberger
  • + 4 authors+ 0 author

Research on highly pathogenic biosafety level 4 (BSL-4) viruses that are classified as Select Agents involves transferring inactivated materials to lower containment levels for further analysis. Compliance with Select Agent and BSL-4 safety regulatio...

(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Molecular Epidemiology, Diagnostics and Management of Viral Pathogens)
  • Review
  • Open Access
3 Citations
2,280 Views
18 Pages

The Frontier of Entomo-Virology: Applications and Tools for Virus and Vector Surveillance

  • Poliana da Silva Lemos,
  • Mayron Mielly Morais Pacheco,
  • Bruna Laís Sena do Nascimento,
  • Mônica Silva Coelho and ,
  • Luciano Chaves Franco Filho,
  • Daniel Damous Dias,
  • Leonardo Sena,
  • Sandro Patroca da Silva and
  • Maria Anice Mureb Sallum
  • + 4 authors+ 0 author

The term ‘entomo-virology’ arose because of the confluence of entomology and virology, focused on deepening the knowledge about the interactions between vectors and viruses and the aspects that involve hosts and the environment. Based on...

(This article belongs to the Section Parasitic Pathogens)
  • Case Report
  • Open Access
1,204 Views
7 Pages

Nocardia cyriacigeorgica in a Mallard (Anas platyrhynchos) from Arizona, USA

  • Susan Knowles,
  • Brenda M. Berlowski-Zier,
  • Anne Justice-Allen,
  • Barbara L. Bodenstein and
  • Jeffrey M. Lorch

Nocardia spp. are opportunistic pathogens of humans, domestic animals, and wildlife that can cause high levels of morbidity and mortality. Here, we present a unique case of nocardial airsacculitis in a free-ranging mallard (Anas platyrhynchos) from A...

  • Brief Report
  • Open Access
1,206 Views
11 Pages

Reexamining a Host-Associated Genomic Diversity of Bean Golden Mosaic Virus (BGMV) Isolates from Phaseolus Species and Other Fabaceae Hosts

  • Luciane de Nazaré Almeida dos Reis,
  • Josiane Goulart Batista,
  • Maria Luiza Fernandes de Oliveira,
  • Maria Esther de Noronha Fonseca and ,
  • Josias Corrêa de Faria,
  • Francisco José Lima Aragão,
  • Leonardo Silva Boiteux and
  • Rita de Cássia Pereira-Carvalho
  • + 3 authors+ 0 author

Beans (Phaseolus vulgaris and P. lunatus) are the major hosts of bean golden mosaic begomovirus (BGMV). Robust taxonomic criteria were established for Begomovirus species demarcation. However, DNA–A identities among BGMV isolates display a cont...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
1 Citations
2,716 Views
13 Pages

Trends of Antibiotic Resistance Patterns and Bacteriological Profiles of Pathogens Associated with Genitourinary Infections in Secondary Healthcare Facilities in the Volta Region of Ghana

  • Hayford Odoi,
  • Naodiah Opoku,
  • Brigham Adusei,
  • Kenneth Danquah and ,
  • Gilbert Vordzogbe,
  • Divine Mayer,
  • Araba Hutton-Nyameaye,
  • Jonathan Jato,
  • Samuel O. Somuah and
  • Cornelius C. Dodoo
  • + 11 authors+ 6 authors

Urogenital infections contribute greatly to both hospital- and community-acquired infections. In Ghana, the prevalence of resistance to commonly used antibiotics is relatively high. This study sought to evaluate the antibiotic sensitivity of bacteria...

(This article belongs to the Section Bacterial Pathogens)
  • Article
  • Open Access
3 Citations
2,522 Views
23 Pages

Defining Soilborne Pathogen Complexes Provides a New Foundation for the Effective Management of Faba Bean Root Diseases in Ethiopia

  • Solomon Yilma,
  • Berhanu Bekele,
  • Joop Van Leur,
  • Ming Pei You and ,
  • Seid-Ahmed Kemal,
  • Danièle Giblot-Ducray,
  • Kelly Hill,
  • Thangavel Selvaraji,
  • Alemu Lencho and
  • Martin J. Barbetti
  • + 6 authors+ 1 author

Soilborne diseases cause losses of 45–70% in faba bean in Ethiopia. Studies were undertaken to define soilborne pathogens and their complexes in Ethiopia. First, the severity of root rot was assessed in 150 field sites across seven Ethiopian re...

(This article belongs to the Special Issue An Update on Fungal Infections)
  • Article
  • Open Access
8 Citations
2,400 Views
19 Pages

Macrophages are a principal pulmonary source of type I and III interferons (IFNs), initiating and coordinating the early antiviral response to respiratory viral infections. Yet the contribution of macrophage-derived IFNs to host defense during human...

(This article belongs to the Special Issue New Insights into Viral Pathogenesis, Host Immune Responses and Immunotherapies)
  • Review
  • Open Access
2,389 Views
15 Pages

Epidemiology of Chronic Hepatitis C in First Nations Populations in Canadian Prairie Provinces

  • Kate P. R. Dunn,
  • Dennis Wardman,
  • Maxim Trubnikov,
  • Chris Sarin and ,
  • Tom Wong,
  • Hongqun Liu and
  • Samuel S. Lee
  • + 2 authors+ 0 author

Current structural barriers experienced by First Nations in Canada shape access and engagement for testing and treatment of hepatitis C virus (HCV) infections. This non-systematic informative review considers transdisciplinary perspectives, regional...

  • Article
  • Open Access
3 Citations
1,482 Views
22 Pages

Transcriptome Analysis and CFEM Gene Overexpression in Metschnikowia bicuspidata Under Hemocyte and Iron Ion Stress

  • Bingnan Zuo,
  • Xiaodong Li,
  • Ji Zhang,
  • Bingyu Li and ,
  • Na Sun and
  • Fang Liang
  • + 1 author+ 0 author

The “milky disease” in Chinese mitten crabs (Eriocheir sinensis), caused by Metschnikowia bicuspidata, poses significant threats to aquaculture, though its pathogenic mechanisms remain poorly understood. This study employs transcriptomic...

  • Article
  • Open Access
3 Citations
2,489 Views
11 Pages

Implementation of a Laboratory-Developed Test for the Diagnosis of Mycoplasma pneumoniae Using a High-Throughput Approach

  • Valeria Conciatori,
  • Sarah Di Sopra,
  • Elisa Franchin,
  • Ioannis Bekas and ,
  • Giuseppe Di Pietra,
  • Ignazio Castagliuolo,
  • Cristiano Salata and
  • Claudia Del Vecchio
  • + 3 authors+ 0 author

Mycoplasma pneumoniae is a significant causative agent of atypical pneumonia in both children and adults. Timely and accurate diagnosis is crucial for appropriate patient management. Conventional methods for detecting M. pneumoniae, such as culture a...

(This article belongs to the Section Bacterial Pathogens)
  • Review
  • Open Access
4 Citations
2,526 Views
13 Pages

Climate change and air pollution are reshaping viral circulation patterns and increasing host vulnerability, amplifying the burden of respiratory illness in early childhood. This narrative review synthesizes current evidence on how environmental expo...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
1,347 Views
13 Pages

Atmospheric Carbon Dioxide Modifies the Antimicrobial Activity and Oxidative Stress Generated by Ciprofloxacin in Escherichia coli

  • Viviana Cano Aristizábal,
  • Elia Soledad Mendoza Ocampo,
  • Melisa de los Ángeles Quinteros,
  • María Gabriela Paraje and
  • Paulina Laura Páez

The accelerated increase in atmospheric CO2 concentration is one of the most pressing problems at present. It is possible that this increase causes slight modifications in intracellular CO2. The aim of this work was to determine whether CO2 at differ...

  • Article
  • Open Access
5 Citations
2,999 Views
17 Pages

Deoxycholic Acid Mitigates Necrotic Enteritis Through Selective Inhibition of Pathobionts and Enrichment of Specific Lactic Acid Bacteria

  • Melanie A. Whitmore,
  • Jiaqing Guo,
  • Dohyung M. Kim,
  • Jing Liu and ,
  • Isabel Tobin and
  • Guolong Zhang
  • + 1 author+ 0 author

Necrotic enteritis (NE), caused by Clostridium perfringens, poses significant economic challenges to the global poultry industry. The widening ban on in-feed antibiotics in livestock production underscores the need for alternative strategies to comba...

(This article belongs to the Section Vaccines and Therapeutic Developments)
  • Article
  • Open Access
3 Citations
3,520 Views
13 Pages

Mytilus galloprovincialis as a Natural Reservoir of Vibrio harveyi: Insights from GFP-Tagged Strain Tracking

  • Arkaitz Almaraz,
  • Flor O. Uriarte,
  • María González-Rivacoba,
  • Inés Arana and ,
  • Itziar Arranz-Veiga,
  • Beñat Zaldibar and
  • Maite Orruño
  • + 2 authors+ 0 author

Vibrios are widespread in marine environments, and their persistence is often linked to natural reservoirs such as filter-feeding bivalves. This study investigated the capacity of the Mediterranean mussel, Mytilus galloprovincialis, to act as a reser...

  • Communication
  • Open Access
3 Citations
981 Views
11 Pages

A Note on the Association Between Climatological Conditions and the Presence of Coxiella burnetii in the Milk-Tank of Dairy Sheep and Goat Farms in Greece

  • Eleni I. Katsarou,
  • Themistoklis Giannoulis,
  • Charalambia K. Michael,
  • Daphne T. Lianou and ,
  • Natalia G. C. Vasileiou,
  • Nikolaos Solomakos,
  • Angeliki I. Katsafadou,
  • Vasia S. Mavrogianni,
  • Dimitriοs C. Chatzopoulos and
  • George C. Fthenakis
  • + 5 authors+ 0 author

The specific objectives of the current paper were the assessment of potential associations of weather conditions with the presence of Coxiella burnetii in the milk-tank of sheep and goat farms and the investigation for possible interactions between w...

  • Article
  • Open Access
10 Citations
3,083 Views
12 Pages

Restoring Control: Real-World Success with Imipenem–Relebactam in Critical MDR Infections—A Multicenter Observational Study

  • Andrea Marino,
  • Giuseppe Pipitone,
  • Emmanuele Venanzi Rullo,
  • Federica Cosentino and ,
  • Rita Ippolito,
  • Roberta Costa,
  • Sara Bagarello,
  • Ylenia Russotto,
  • Chiara Iaria and
  • Giuseppe Nunnari
  • + 6 authors+ 1 author

Background: Multidrug-resistant (MDR) Gram-negative infections, particularly those caused by carbapenem-resistant Enterobacterales (CRE) and difficult-to-treat Pseudomonas aeruginosa (DTR-Pa), present a growing global healthcare challenge, especially...

(This article belongs to the Special Issue Drug Resistant Pathogens: Diagnosis, Treatment, and Global Health Implications)
  • Case Report
  • Open Access
4 Citations
3,241 Views
11 Pages

First Confirmed Case of Zoonotic Transmission of RR-TB from a Dog to a Human, a Neglected Mode of Mycobacterium tuberculosis Infection—Case Report and Review of the Literature

  • Ljiljana Zmak,
  • Marija Gomercic Palcic,
  • Mihaela Obrovac,
  • Ivana Folnozic and ,
  • Drazen Strelec,
  • Irena Reil,
  • Ana Miljan,
  • Maja Zdelar-Tuk,
  • Sanja Duvnjak and
  • Silvio Spicic
  • + 7 authors+ 2 authors

Mycobacterium (M.) tuberculosis mostly spreads from active tuberculosis (TB) patients to human contacts, although human-to-animal and animal-to-human transmission has been described. Here, we present a rare case of rifampicin-resistant tuberculosis (...

(This article belongs to the Special Issue Emerging and Neglected Pathogens in the Balkans)
  • Article
  • Open Access
3 Citations
1,840 Views
25 Pages

NOD2 (Nucleotide-Binding Oligomerization Domain-Containing Protein 2)-Mediated Modulation of the Immune Response Induced by BCG (Bacillus Calmette-Guérin) Bacilli

  • Magdalena Jurczak,
  • Joanna Kaczmarek,
  • Magdalena Kowalewska-Pietrzak,
  • Paulina Stelmach and
  • Magdalena Druszczynska

The Bacillus Calmette-Guérin (BCG) vaccine confers broad, non-specific immunity that may bolster defenses against respiratory viruses. While NOD2 (nucleotide-binding oligomerization domain-containing protein 2)-driven pathways are central to i...

  • Article
  • Open Access
8 Citations
2,873 Views
16 Pages

Isolation and Molecular Characterization of Antimicrobial-Resistant Bacteria from Vegetable Foods

  • Annamaria Castello,
  • Chiara Massaro,
  • Erine Seghers,
  • Clelia Ferraro and ,
  • Antonella Costa,
  • Rosa Alduina and
  • Cinzia Cardamone
  • + 2 authors+ 0 author

Antimicrobial resistance (AMR) poses a growing threat to global health, and its spread through the food chain is gaining increasing attention. While AMR in food of animal origin has been extensively studied, less is known about its prevalence in plan...

  • Review
  • Open Access
17 Citations
4,838 Views
26 Pages

Current Trends in Approaches to Prevent and Control Antimicrobial Resistance in Aquatic Veterinary Medicine

  • Dongqing Zhao,
  • Konrad Wojnarowski,
  • Paulina Cholewińska and
  • Dušan Palić

The growth of aquaculture production in recent years has revealed multiple challenges, including the rise of antimicrobial resistance (AMR) in aquatic animal production, which is currently attracting significant attention from multiple one-health sta...

  • Article
  • Open Access
1 Citations
1,509 Views
13 Pages

Mitochondrial Genomes of the Blood Flukes Cardicola forsteri and Cardicola orientalis (Trematoda: Aporocotylidae)

  • Jemma Hudson,
  • Sunita B. Sumanam,
  • Bronwyn E. Campbell,
  • Lachlan Coff and ,
  • Barbara F. Nowak,
  • Paul A. Ramsland,
  • Neil D. Young and
  • Nathan J. Bott
  • + 3 authors+ 0 author

Parasitic diseases can be a significant constraint on aquaculture industries, which continue to develop in response to the rise in global demand for sustainable protein sources. Blood flukes, Cardicola forsteri and Cardicola orientalis, are economica...

(This article belongs to the Special Issue Genomic Insights into Parasites of Fishes)
  • Article
  • Open Access
1 Citations
1,996 Views
19 Pages

Potential for Duplexed, In-Tandem gRNA-Mediated Suppression of Two Essential Genes of Tomato Leaf Curl New Delhi Virus in Crop Plants

  • Saher Naveed,
  • Judith K. Brown,
  • Muhammad Mubin,
  • Nazir Javed and
  • Muhammad Shah Nawaz-ul-Rehman

Tomato leaf curl New Delhi virus (ToLCNDV) is among the most prevalent and widely distributed begomovirus infecting chili pepper (Capsicum annuum) and tomato in the Indian subcontinent. In this study, a guide RNA (gRNA) sequence-CRISPR-Cas9 approach...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
7 Citations
2,296 Views
16 Pages

Thirteen-Year Sequelae of Marburg Virus Disease Survival: Persistent Cardiometabolic, Immunometabolic, and Haematological Alterations in the Absence of Psychological Morbidity

  • Jennifer Serwanga,
  • Raymond Ernest Kaweesa,
  • Joseph Katende Ssebwana,
  • Goeffrey Odoch and ,
  • Raymond Reuel Wayesu,
  • Anne Daphine Ntabadde,
  • Deborah Mukisa,
  • Peter Ejou,
  • FiloStudy Team and
  • Pontiano Kaleebu
  • + 6 authors+ 1 author

Background: Marburg virus disease (MVD) is a highly lethal filoviral infection, yet its long-term health consequences remain poorly understood. We present one of the most temporally distant evaluations of MVD survivors, conducted 13 years post-outbre...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
1 Citations
1,307 Views
11 Pages

SNX11 Deletion Inhibits Dabie bandavirus Infection by Interfering with the Assembly of V-ATPase

  • Tiezhu Liu,
  • Xueqi Wang,
  • Yang Fang,
  • Ping Zhang and ,
  • Qiang Sun,
  • Jiandong Li and
  • Shiwen Wang
  • + 2 authors+ 0 author

SNX11, a sorting nexin protein localized on the endosomal membrane, is an important protein closely related to protein sorting and endosomal trafficking. Previously, through a genome-wide CRISPR screening, we identified SNX11 as a critical protein fo...

  • Article
  • Open Access
1 Citations
2,260 Views
10 Pages

Temporal Parasitemia Trends Predict Risk and Timing of Experimental Cerebral Malaria in Mice Infected by Plasmodium berghei ANKA

  • Peyton J. Murin,
  • Cláudio Tadeu Daniel-Ribeiro,
  • Leonardo José Moura Carvalho and
  • Yuri Chaves Martins

Background: Experimental models using Plasmodium berghei ANKA (PbA)-infected mice have been essential for uncovering cerebral malaria (CM) pathogenesis. However, variability in experimental CM (ECM) incidence, onset, and mortality introduce challenge...

(This article belongs to the Special Issue Parasitic Diseases in the Contemporary World)
  • Article
  • Open Access
10 Citations
2,474 Views
14 Pages

Comprehensive Survey of PCV2 and PCV3 in Domestic Pigs and Wild Boars Across Portugal: Prevalence, Geographical Distribution and Genetic Diversity

  • Bernardo Almeida,
  • Margarida D. Duarte,
  • Ana Duarte,
  • Teresa Fagulha and ,
  • Fernanda Ramos,
  • Tiago Luís,
  • Inês Caetano,
  • Sílvia C. Barros,
  • Fábio Abade dos Santos and
  • Ana Margarida Henriques
  • + 5 authors+ 0 author

Porcine circoviruses are significant pathogens that affect swine populations worldwide, with implications for animal health and productivity. While PCV2 is well-documented, particularly due to widespread vaccination programs, PCV3 is less understood,...

(This article belongs to the Special Issue Current Challenges in Veterinary Virology)
  • Article
  • Open Access
1,895 Views
12 Pages

Dientamoeba fragilis in Ulcerative Colitis: Analysis of Clinical Findings and Biochemical Parameters

  • Ismail Taskiran,
  • Erdogan Malatyali,
  • Ibrahim Yildiz,
  • Levent Durmus Guler and ,
  • Evren Tileklioglu,
  • Hatice Ertabaklar and
  • Sema Ertug
  • + 2 authors+ 0 author

Although Dientamoeba fragilis is a common protozoan in humans, its pathogenicity and clinical significance in human diseases remain poorly understood. This study aimed to determine the frequency of D. fragilis in adult ulcerative colitis patients and...

(This article belongs to the Section Parasitic Pathogens)
  • Systematic Review
  • Open Access
6 Citations
4,525 Views
20 Pages

Undetectable = Untransmittable: A Cross-Population Systematic Review and Meta-Analysis on Awareness and Acceptance

  • Nikolaos Georgiadis,
  • Andreas Katsimpris,
  • Perry N. Halkitis,
  • Evridiki Kaba and ,
  • Georgina Tzanakaki,
  • Tonia Vassilakou,
  • Apostolos Beloukas and
  • Theodoros N. Sergentanis
  • + 3 authors+ 0 author

The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to assess the global prevalence of awa...

  • Brief Report
  • Open Access
1,197 Views
7 Pages

Evaluating the Antiviral Activity of Termin-8 and Finio Against a Surrogate ASFV-like Algal Virus

  • Amanda Palowski,
  • Francisco Domingues,
  • Othmar Lopez,
  • Nicole Holcombe and ,
  • Gerald Shurson and
  • Declan C. Schroeder
  • + 1 author+ 0 author

The objective of this study was to evaluate the time-course of incubation for the potential preventative mitigation of megaviruses using Termin-8 (a formaldehyde-based product) and Finio (non-formaldehyde solution) from Anitox. Emiliania huxleyi viru...

(This article belongs to the Special Issue Emergence and Control of African Swine Fever: Second Edition)
  • Article
  • Open Access
2 Citations
2,048 Views
11 Pages

Investigation of Leishmania infantum Infection and Feeding Preferences of Lutzomyia longipalpis During Deltamethrin (4%) Dog Collar Intervention

  • Gabriel F. F. Rodrigues,
  • Keuryn A. M. Luz-Requena,
  • Bruno S. Mathias,
  • Tania M. T. Suto and ,
  • Rosemari Suto,
  • Luciana T. R. Rocha,
  • Osias Rangel,
  • Katia D. S. Bresciani,
  • Susy M. P. Sampaio and
  • Karin Kirchgatter
  • + 6 authors+ 1 author

Leishmaniasis is a zoonotic disease caused by protozoa of the genus Leishmania, transmitted by phlebotomine sand flies. Understanding the feeding behavior and infection rates of these vectors is crucial for disease surveillance and control. We aimed...

(This article belongs to the Section Parasitic Pathogens)

of 3

XFacebookLinkedIn
Pathogens - ISSN 2076-0817