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Journal of Personalized Medicine, Volume 13, Issue 4

April 2023 - 131 articles

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Cover Story: Long-term survival after emergency colorectal cancer surgery is low, and its estimation is most frequently neglected. We retrospectively studied 437 patients who underwent emergency surgery for colorectal cancer. We created a multivariate logistic regression model that included eight independent prognostic factors: age > 63 years, Charlson score > 4, revised cardiac risk index, lymphocytes/neutrophils ratio, tumor site, macroscopic tumoral invasion, surgery type, and lymph node dissection, with an area under the curve of 0.831. The nomogram created has a good individual prediction of overall survival and may support clinicians when informing patients about prognosis. View this paper

Articles (131)

  • Communication
  • Open Access
4 Citations
2,493 Views
8 Pages

Contrast-Induced Acute Kidney Injury and Endothelial Dysfunction: The Role of Vascular and Biochemical Parameters

  • Adolfo Marco Perrotta,
  • Antonietta Gigante,
  • Silverio Rotondi,
  • Paolo Menè,
  • Adriano Notturni,
  • Stefano Schiavetto,
  • Gaetano Tanzilli,
  • Chiara Pellicano,
  • Giuseppe Guaglianone and
  • Francesca Tinti
  • + 4 authors

21 April 2023

Introduction: Contrast-induced acute kidney injury (CIAKI) is one of the main causes of acute renal failure in hospitalized patients, following the administration of iodinated contrast medium used for CT scans and angiographic procedures. CIAKI deter...

  • Article
  • Open Access
1 Citations
2,595 Views
13 Pages

Transcription Factor ATF3 Participates in DeltaNp63-Mediated Proliferation of Corneal Epithelial Cells

  • Yi-Jen Hsueh,
  • Yaa-Jyuhn James Meir,
  • Hui-Yi Hsiao,
  • Chao-Min Cheng,
  • Hui-Kang David Ma,
  • Wei-Chi Wu and
  • Hung-Chi Chen

21 April 2023

Understanding the regulatory mechanisms underlying corneal epithelial cell (CEC) proliferation in vitro may provide the means to boost CEC production in cell therapy for ocular disorders. The transcription factor ΔNp63 plays a crucial role in t...

  • Review
  • Open Access
9 Citations
4,763 Views
11 Pages

SARS-CoV-2 Footprints in the Placenta: What We Know after Three Years of the Pandemic

  • Valentina Tosto,
  • Arun Meyyazhagan,
  • Malek Alqasem,
  • Valentina Tsibizova and
  • Gian Carlo Di Renzo

21 April 2023

As the COVID-19 pandemic continues into its third year, there is accumulating evidence on the consequences of maternal infection. Emerging data indicate increased obstetrics risks, including maternal complications, preterm births, impaired intrauteri...

  • Article
  • Open Access
3 Citations
4,303 Views
11 Pages

MRI Characteristics and Alterations in Patellar Height in Patients with Patellar Tendinopathy—A Retrospective Study

  • Kim Loose,
  • Sophie Pennekamp,
  • Wolfgang Hitzl,
  • Maximilian Willauschus,
  • Johannes Rüther,
  • Sandeep Silawal,
  • Philipp Schuster,
  • Hermann Josef Bail,
  • Michael Millrose and
  • Markus Geßlein

21 April 2023

(1) Background: Patellar tendinopathy (PT) is an overuse condition of the knee extensor mechanism characterized by ventral knee pain at the lower pole of the patella and limited functionality. (2) Methods: In this retrospective study, a group of pati...

  • Systematic Review
  • Open Access
27 Citations
6,876 Views
19 Pages

Investigating the Role of Maintenance TMS Protocols for Major Depression: Systematic Review and Future Perspectives for Personalized Interventions

  • Giacomo d’Andrea,
  • Gianluca Mancusi,
  • Maria Chiara Santovito,
  • Carlotta Marrangone,
  • Fabrizio Martino,
  • Mario Santorelli,
  • Andrea Miuli,
  • Francesco Di Carlo,
  • Maria Salvina Signorelli and
  • Massimo Clerici
  • + 2 authors

21 April 2023

Repetitive Transcranial Magnetic Stimulation (rTMS) has been approved by the FDA as an effective intervention for Treatment-Resistant Depression (TRD). However, there is little evidence about maintenance protocol necessity. The aim of this systematic...

  • Case Report
  • Open Access
2,644 Views
8 Pages

Uroperitoneum as a Complication of Laparoscopic Cholecystectomy: A Case Report

  • Charalampos Kefalas,
  • Alexandra Menni,
  • Eleni Karlafti,
  • Stavros Panidis,
  • Georgios Chatziantoniou,
  • Konstantina Katsiafliaka,
  • Despina Krokou,
  • Aristeidis Ioannidis,
  • Patroklos Goulas and
  • Smaro Netta
  • + 1 author

21 April 2023

Background: Bladder rupture is more frequently encountered in blunt pelvic trauma, but can also be spontaneous or iatrogenic. Laparoscopic repair has been widely used during the last few years as a treatment for intraperitoneal bladder perforation. T...

  • Review
  • Open Access
6 Citations
2,912 Views
13 Pages

Bortezomib Pharmacogenetic Biomarkers for the Treatment of Multiple Myeloma: Review and Future Perspectives

  • Antonio Sanz-Solas,
  • Jorge Labrador,
  • Raquel Alcaraz,
  • Beatriz Cuevas,
  • Raquel Vinuesa,
  • María Victoria Cuevas and
  • Miriam Saiz-Rodríguez

20 April 2023

Multiple myeloma (MM) is a hematological neoplasm for which different chemotherapy treatments are used with several drugs in combination. One of the most frequently used drugs for the treatment of MM is the proteasome inhibitor bortezomib. Patients t...

  • Review
  • Open Access
8 Citations
3,006 Views
19 Pages

Utilization of Circulating Tumor Cells in the Management of Solid Tumors

  • Peter C. Kurniali,
  • Michael H. Storandt and
  • Zhaohui Jin

20 April 2023

Circulating tumor cells (CTCs) are tumor cells shed from the primary tumor into circulation, with clusters of CTCs responsible for cancer metastases. CTC detection and isolation from the bloodstream are based on properties distinguishing CTCs from no...

  • Article
  • Open Access
3 Citations
2,683 Views
10 Pages

20 April 2023

Purpose: To investigate the incidence of central nervous system (CNS) diseases in adult patients with voiding dysfunction and videourodynamics (VUDS) proven urethral sphincter dysfunction. Methods: This retrospective analysis reviewed the medical cha...

  • Article
  • Open Access
13 Citations
9,395 Views
12 Pages

Radiation Exposure and Frequency of Dental, Bitewing and Occlusal Radiographs in Children and Adolescents

  • Ina Manuela Schüler,
  • Christoph-Ludwig Hennig,
  • Rika Buschek,
  • Rebecca Scherbaum,
  • Collin Jacobs,
  • Marcel Scheithauer and
  • Hans-Joachim Mentzel

20 April 2023

Dental radiographs are valuable diagnostic aids for oral healthcare, but exposure to ionizing radiation carries health risks, especially in children due to their high radio-sensitivity. Valid reference values for intraoral radiographs in children and...

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