You are currently viewing a new version of our website. To view the old version click .

Journal of Personalized Medicine, Volume 10, Issue 2

June 2020 - 35 articles

Cover Story: Informing providers and patients about genetic tests results is becoming increasingly important as genomic medicine expands into all areas of medicine. As there are no standards for return of results (RoR), we examined the planned processes for returning actionable variants in 109 genes and SNVs to consenting participants and providers across 10 sites in the electronic Medical Record and Genomics (eMERGE) network. Marked heterogeneity of RoR was identified, due to differences in population, disease focus, and institutional requirements. This article describes the “real world” of RoR in genomic medicine and provides foundational information for the development of common RoR protocols. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (35)

  • Review
  • Open Access
24 Citations
6,829 Views
12 Pages

Implementation of MALDI Mass Spectrometry Imaging in Cancer Proteomics Research: Applications and Challenges

  • Eline Berghmans,
  • Kurt Boonen,
  • Evelyne Maes,
  • Inge Mertens,
  • Patrick Pauwels and
  • Geert Baggerman

Studying the proteome–the entire set of proteins in cells, tissues, organs and body fluids—is of great relevance in cancer research, as differential forms of proteins are expressed in response to specific intrinsic and extrinsic signals....

  • Article
  • Open Access
11 Citations
4,812 Views
8 Pages

Background and Objective: Since the treatment outcome with oral anti-diabetics differs between individuals, the objective of this study is to evaluate the significance of rs622342 in SLC22A1, CYP2C9*2 (rs1799853) and CYP2C9*3 (rs1057910) with regard...

  • Article
  • Open Access
3 Citations
4,116 Views
10 Pages

In thyroid neoplastic pathology, the BRAF V600E mutation is shown to be involved in the oncogenesis of papillary thyroid cancer and its subtypes. The purpose of this study is to evaluate the correlation between the mutation of the BRAF V600E oncogene...

  • Review
  • Open Access
4 Citations
5,576 Views
9 Pages

Recent progress in Omics technologies has started to empower personalized healthcare development at a thorough biomolecular level. Omics have subsidized medical breakthroughs that have started to enter clinical proceedings. The use of this scientific...

  • Article
  • Open Access
32 Citations
11,616 Views
10 Pages

Risk Factors Associated with Low Back Pain among A Group of 1510 Pregnant Women

  • Aleksandra Bryndal,
  • Marian Majchrzycki,
  • Agnieszka Grochulska,
  • Sebastian Glowinski and
  • Agnieszka Seremak-Mrozikiewicz

Background: Low Back Pain (LBP) is a frequent, very common, and costly health problem. LBP, which occurs during pregnancy, may become a lifelong problem. The aim of this study was to determine the risk factors associated with LBP in pregnant women. M...

  • Article
  • Open Access
13 Citations
4,532 Views
13 Pages

Nursing around the world is developing very dynamically and nurses are undertaking increasingly complex tasks. The extension of entitlements for nurses in Poland in the area of writing prescriptions and referrals for diagnostic tests seems to be a re...

  • Article
  • Open Access
4 Citations
9,567 Views
19 Pages

Several active principles from plants could trigger the release of stem cells from the bone marrow. Stem cell mobilizers have shown side effects in patients. Thus, the purpose of this paper is to find the natural products from plants (curcuminoids, g...

  • Article
  • Open Access
4 Citations
4,745 Views
11 Pages

Failure of Achieving Tacrolimus Target Blood Concentration Might Be Avoided by a Wide Genotyping of Transplanted Patients: Evidence from a Retrospective Study

  • Giovanni Pallio,
  • Natasha Irrera,
  • Alessandra Bitto,
  • Federica Mannino,
  • Letteria Minutoli,
  • Michelangelo Rottura,
  • Socrate Pallio,
  • Domenica Altavilla,
  • Angela Alibrandi and
  • Maria Concetta Marciano
  • + 4 authors

Precise tacrolimus treatment in transplanted patients is achieved in the clinical setting by performing therapeutic drug monitoring (TDM) and consequently adjusting therapy. The aim of this study was to retrospectively analyze the variability in tacr...

  • Article
  • Open Access
20 Citations
4,849 Views
14 Pages

Influence of ApoE Genotype and Clock T3111C Interaction with Cardiovascular Risk Factors on the Progression to Alzheimer’s Disease in Subjective Cognitive Decline and Mild Cognitive Impairment Patients

  • Valentina Bessi,
  • Juri Balestrini,
  • Silvia Bagnoli,
  • Salvatore Mazzeo,
  • Giulia Giacomucci,
  • Sonia Padiglioni,
  • Irene Piaceri,
  • Marco Carraro,
  • Camilla Ferrari and
  • Laura Bracco
  • + 2 authors

Background: Some genes could interact with cardiovascular risk factors in the development of Alzheimer’s disease. We aimed to evaluate the interaction between ApoE ε4 status, Clock T3111C and Per2 C111G polymorphisms with cardiovascular...

  • Article
  • Open Access
7 Citations
4,903 Views
13 Pages

Equilibrium CT Texture Analysis for the Evaluation of Hepatic Fibrosis: Preliminary Evaluation against Histopathology and Extracellular Volume Fraction

  • Jason Yeung,
  • Balaji Ganeshan,
  • Raymond Endozo,
  • Andrew Hall,
  • Simon Wan,
  • Ashley Groves,
  • Stuart A. Taylor and
  • Steve Bandula

Background: Evaluate equilibrium contrast-enhanced CT (EQ-CT) texture analysis (EQ-CTTA) against histologically-quantified fibrosis, serum-based enhanced liver fibrosis panel (ELF) and imaging-based extracellular volume fraction (ECV) in chronic hepa...

of 4

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
J. Pers. Med. - ISSN 2075-4426