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Diagnostics, Volume 12, Issue 4

April 2022 - 249 articles

Cover Story: Personalized diagnosis for thyroid nodules benefits from a combination of imagery and molecular biomarkers, as well as artificial intelligence algorithms, which are used more and more in our timeline. Functional imaging diagnosis such as SPECT, PET, or fused images (SPECT/CT, PET/CT, PET/MRI), is exploited at maximum in thyroid nodules, with a long history in the past and a bright future with many suitable radiotracers that could properly contribute to diagnosing malignancy in thyroid nodules. In this way, patients will be spared from surgery complications, and apparently more expensive diagnostic workouts will financially compensate each patient and also the healthcare system. For those in need of personalized therapeutic management, PRRT and gene therapies are in continuous development supporting thyroid carcinoma’s treatment gap. View this paper
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Articles (249)

  • Article
  • Open Access
14 Citations
2,693 Views
11 Pages

Use of a Feed-Forward Back Propagation Network for the Prediction of Small for Gestational Age Newborns in a Cohort of Pregnant Patients with Thrombophilia

  • Petronela Vicoveanu,
  • Ingrid Andrada Vasilache,
  • Ioana Sadiye Scripcariu,
  • Dragos Nemescu,
  • Alexandru Carauleanu,
  • Dragos Vicoveanu,
  • Ana Roxana Covali,
  • Catalina Filip and
  • Demetra Socolov

(1) Background: Fetal growth restriction is a relatively common disorder in pregnant patients with thrombophilia. New artificial intelligence algorithms are a promising option for the prediction of adverse obstetrical outcomes. The aim of this study...

  • Article
  • Open Access
14 Citations
5,021 Views
17 Pages

Multicentric Evaluation of SeeGene Allplex Real-Time PCR Assays Targeting 28 Bacterial, Microsporidal and Parasitic Nucleic Acid Sequences in Human Stool Samples

  • Felix Weinreich,
  • Andreas Hahn,
  • Kirsten Alexandra Eberhardt,
  • Simone Kann,
  • Thomas Köller,
  • Philipp Warnke,
  • Susann Dupke,
  • Denise Dekker,
  • Jürgen May and
  • Hagen Frickmann
  • + 1 author

Prior to the implementation of new diagnostic techniques, a thorough evaluation is mandatory in order to ensure diagnostic reliability. If positive samples are scarcely available, however, such evaluations can be difficult to perform. Here, we evalua...

  • Article
  • Open Access
6 Citations
6,035 Views
14 Pages

Urine Flow Cytometry Parameter Cannot Safely Predict Contamination of Urine—A Cohort Study of a Swiss Emergency Department Using Machine Learning Techniques

  • Martin Müller,
  • Nadine Sägesser,
  • Peter M. Keller,
  • Spyridon Arampatzis,
  • Benedict Steffens,
  • Simone Ehrhard and
  • Alexander B. Leichtle

Background: Urine flow cytometry (UFC) analyses urine samples and determines parameter counts. We aimed to predict different types of urine culture growth, including mixed growth indicating urine culture contamination. Methods: A retrospective cohort...

  • Review
  • Open Access
37 Citations
36,157 Views
15 Pages

Imaging of the Temporomandibular Joint

  • Seyed Mohammad Gharavi,
  • Yujie Qiao,
  • Armaghan Faghihimehr and
  • Josephina Vossen

Temporomandibular disorder (TMD) is a common musculoskeletal condition that causes pain and disability for patients and imposes a high financial burden on the healthcare system. The most common cause of TMD is internal derangement, mainly secondary t...

  • Review
  • Open Access
7 Citations
4,603 Views
11 Pages

Surgical Treatment in Silicone Oil-Associated Glaucoma

  • Catalin Cornacel,
  • Otilia-Maria Dumitrescu,
  • Alexandra Catalina Zaharia,
  • Ruxandra Angela Pirvulescu,
  • Mihnea Munteanu,
  • Calin Petru Tataru and
  • Sinziana Istrate

Glaucoma is a vision threatening, not uncommon complication of eyes that have undergone pars plana vitrectomy with silicone oil endotamponade. Although most patients respond well to medical antiglaucoma therapy, there are refractory cases where surge...

  • Article
  • Open Access
6 Citations
2,730 Views
9 Pages

Diagnosing pancreatic malignancy is challenging, especially in patients with chronic pancreatitis (CP). Endoscopic ultrasonography (EUS) is a promising diagnostic procedure for discriminating between malignancy and CP. We aimed to investigate the pre...

  • Case Report
  • Open Access
1 Citations
3,056 Views
9 Pages

Total Pancreatectomy for Multicentric Cystic Neuroendocrine Tumor of the Pancreas: A Case Report

  • Milica Mitrovic-Jovanovic,
  • Nikica Grubor,
  • Stefan Milosevic,
  • Aleksandra Jankovic,
  • Katarina Stosic,
  • Slavenko Ostojic,
  • Aleksandar Ninic,
  • Marjan Micev and
  • Jelena Djokic Kovac

Pancreatic neuroendocrine tumors (PNETs) are uncommon pancreatic neoplasms with malignant potential, heterogeneous clinical behavior, as well as imaging appearance. These tumors represent less than 3% of all pancreatic neoplasms with typical CT prese...

  • Article
  • Open Access
16 Citations
3,759 Views
13 Pages

Radiomics for the Prediction of Response to Antifibrotic Treatment in Patients with Idiopathic Pulmonary Fibrosis: A Pilot Study

  • Cheng-Chun Yang,
  • Chin-Yu Chen,
  • Yu-Ting Kuo,
  • Ching-Chung Ko,
  • Wen-Jui Wu,
  • Chia-Hao Liang,
  • Chun-Ho Yun and
  • Wei-Ming Huang

Antifibrotic therapy has changed the treatment paradigm for idiopathic pulmonary fibrosis (IPF); however, a subset of patients still experienced rapid disease progression despite treatment. This study aimed to determine whether CT-based radiomic feat...

  • Article
  • Open Access
3 Citations
2,694 Views
11 Pages

Parkinson’s Disease Symptoms Associated with Developing On-State Axial Symptoms Early after Subthalamic Deep Brain Stimulation

  • Gustavo Fernández-Pajarín,
  • Ángel Sesar,
  • José Luis Relova,
  • Begoña Ares,
  • Isabel Jiménez,
  • Miguel Gelabert-González,
  • Eduardo Arán and
  • Alfonso Castro

Background: The relationship between axial symptoms in Parkinson’s disease (PD) and subthalamic deep brain stimulation (STN-DBS) is still unclear. Purpose: We searched for particular clinical characteristics before STN-DBS linked to on-state ax...

  • Case Report
  • Open Access
1 Citations
2,997 Views
5 Pages

To date, along with the progress of new technology and computer program development, the high-resolution computed tomography (HRCT) had been applied in different clinical application, such as HRCT for coronary angiography. In the current neuroimaging...

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Diagnostics - ISSN 2075-4418