Advances in Diagnostics of Head and Neck Cancer

Dear Colleagues,

The relative 5-year survival rate for tumors in the head and neck area, including oral cavity, pharynx, sinonasal cavity, and salivary glands, has increased over the last 40 years. Tobacco smoke, alcohol abuse, and viral infection with human papillomavirus are risk factors. Molecular alterations regarding genetic and epigenetic aberrations in carcinogenesis of the head and neck have been identified. Head and neck cancer is a common disease and requires an interdisciplinary involvement of physicians from many specializations. Together with molecular biologists, geneticists, radiotherapists, and pathologists, surgeons deal with this issue. The main goal of this cooperation and a great deal of research conducted around the world is to develop diagnostic methods that shorten the patient’s waiting time for treatment proposals and allow the most effective treatment method to be used. This will make it possible to get better results in the treatment of patients with head and neck tumors. The growing number of tumors in the head and neck area is the main reason for searching for new diagnostic biomarkers. Moreover, the expanded knowledge of molecular pathogenesis for head and neck cancerogenesis can be exploited for improving the diagnosis and treatment of patients with head and neck cancer.

This Special Issue aims to enrich the research area of head and neck tumors by gathering participation to identify diagnostic biomarkers for head and neck tumors, and to discuss new research developments in the molecular pathology of head and neck malignancies.

To contribute to the knowledge base on diagnosis of head and neck malignancies, the following topics will be considered: the molecular biology of head and neck cancer, the tumor microenvironment, and the prognostic and predictive roles of biomarkers.

Prof. Dr. Maciej Misiolek
Prof. Dr. Joanna Katarzyna Strzelczyk
Guest Editors

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