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Diagnostics, Volume 12, Issue 4

April 2022 - 249 articles

Cover Story: Personalized diagnosis for thyroid nodules benefits from a combination of imagery and molecular biomarkers, as well as artificial intelligence algorithms, which are used more and more in our timeline. Functional imaging diagnosis such as SPECT, PET, or fused images (SPECT/CT, PET/CT, PET/MRI), is exploited at maximum in thyroid nodules, with a long history in the past and a bright future with many suitable radiotracers that could properly contribute to diagnosing malignancy in thyroid nodules. In this way, patients will be spared from surgery complications, and apparently more expensive diagnostic workouts will financially compensate each patient and also the healthcare system. For those in need of personalized therapeutic management, PRRT and gene therapies are in continuous development supporting thyroid carcinoma’s treatment gap. View this paper
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Articles (249)

  • Case Report
  • Open Access
2 Citations
3,797 Views
7 Pages

Clear cell odontogenic carcinoma (CCOC) is a rare, aggressive epithelial neoplasm of the jaw first described in 1985 by Hansen and classified as an odontogenic malignant tumor in the 2005 WHO classification. To date, only 117 cases have been reported...

  • Article
  • Open Access
94 Citations
5,766 Views
12 Pages

Glioma Tumors’ Classification Using Deep-Neural-Network-Based Features with SVM Classifier

  • Ghazanfar Latif,
  • Ghassen Ben Brahim,
  • D. N. F. Awang Iskandar,
  • Abul Bashar and
  • Jaafar Alghazo

The complexity of brain tissue requires skillful technicians and expert medical doctors to manually analyze and diagnose Glioma brain tumors using multiple Magnetic Resonance (MR) images with multiple modalities. Unfortunately, manual diagnosis suffe...

  • Article
  • Open Access
9 Citations
3,964 Views
19 Pages

Novel User-Friendly Application for MRI Segmentation of Brain Resection following Epilepsy Surgery

  • Roberto Billardello,
  • Georgios Ntolkeras,
  • Assia Chericoni,
  • Joseph R. Madsen,
  • Christos Papadelis,
  • Phillip L. Pearl,
  • Patricia Ellen Grant,
  • Fabrizio Taffoni and
  • Eleonora Tamilia

Delineation of resected brain cavities on magnetic resonance images (MRIs) of epilepsy surgery patients is essential for neuroimaging/neurophysiology studies investigating biomarkers of the epileptogenic zone. The gold standard to delineate the resec...

  • Review
  • Open Access
19 Citations
14,114 Views
17 Pages

Diagnosis and Management of Malignant Pleural Effusion: A Decade in Review

  • Blake Jacobs,
  • Ghias Sheikh,
  • Houssein A. Youness,
  • Jean I. Keddissi and
  • Tony Abdo

Malignant pleural effusion (MPE) is a common complication of thoracic and extrathoracic malignancies and is associated with high mortality. Treatment is mainly palliative, with symptomatic management achieved via effusion drainage and pleurodesis. Pl...

  • Article
  • Open Access
6 Citations
2,925 Views
10 Pages

Prevalence of Occult Hepatitis C Virus Infection in Egyptian Patients with Lymphoma: A New Vision

  • Kholoud A. Elkashef,
  • Wafaa A. Emam,
  • Noha M. Mesbah,
  • Dina M. Abo-Elmatty and
  • Asmaa R. Abdel-Hamed

Occult hepatitis C virus infection (OCI) is the absence of HCV RNA in serum and the presence of actively replicating HCV RNA in hepatocytes and peripheral blood mononuclear cells (PBMCs), as evidenced by the presence of antigenomic negative sense sin...

  • Article
  • Open Access
2 Citations
2,279 Views
9 Pages

Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study

  • Katsuhiro Inoue,
  • Ryohei Nakayama,
  • Shiho Isoshima,
  • Shinichi Takase,
  • Tsunehiro Yamahata,
  • Maki Umino,
  • Masayuki Maeda and
  • Hajime Sakuma

Unstable carotid plaques are visualized as high-signal plaques (HSPs) on 3D turbo spin-echo T1-weighted black-blood vessel wall imaging (3D TSE T1-BB VWI). The purpose of this study was to compare manual segmentation and semiautomated segmentation fo...

  • Article
  • Open Access
2 Citations
2,579 Views
9 Pages

Faecal Immunochemical Test Impact on Prognosis of Colorectal Cancer Detected in Symptomatic Patients

  • Jesús Daniel Fernández de Castro,
  • Franco Baiocchi Ureta,
  • Raquel Fernández González,
  • Noel Pin Vieito and
  • Joaquín Cubiella Fernández

The use of the faecal immunochemical test (FIT) to stratify the risk of colorectal cancer (CRC) in symptomatic patients in primary healthcare enables improved referrals to colonoscopy. However, its effect on diagnostic delays or the prognosis of pati...

  • Review
  • Open Access
31 Citations
4,912 Views
12 Pages

Splenic Artery Pseudoaneurysms: The Role of ce-CT for Diagnosis and Treatment Planning

  • Fabio Corvino,
  • Francesco Giurazza,
  • Anna Maria Ierardi,
  • Pierleone Lucatelli,
  • Antonello Basile,
  • Antonio Corvino and
  • Raffaella Niola

Splenic artery pseudoaneurysm (PSA) is a contained vascular wall lesion associated with a high mortality rate, generally related to pancreatitis, trauma, malignancy, iatrogenic injury, and segmental arterial mediolysis. Computed tomography angiograph...

  • Systematic Review
  • Open Access
22 Citations
4,645 Views
11 Pages

Utility of Red Cell Distribution Width (RDW) as a Noninvasive Biomarker for the Diagnosis of Acute Appendicitis: A Systematic Review and Meta-Analysis of 5222 Cases

  • Sachit Anand,
  • Nellai Krishnan,
  • Miro Jukić,
  • Zvonimir Križanac,
  • Carlos Martin Llorente Muñoz and
  • Zenon Pogorelić

Background: Despite great advances in medicine, numerous available laboratory markers, and radiological imaging, the diagnosis of acute appendicitis (AA) in some cases still remains controversial and challenging for clinicians. Because of that, clini...

  • Article
  • Open Access
8 Citations
4,048 Views
12 Pages

Assessment of Maxillary Molars Interradicular Septum Morphological Characteristics as Criteria for Ideal Immediate Implant Placement—The Advantages of Cone Beam Computed Tomography Analysis

  • Zlata Rajkovic Pavlovic,
  • Pavle Milanovic,
  • Milica Vasiljevic,
  • Nemanja Jovicic,
  • Aleksandra Arnaut,
  • Djurdjina Colic,
  • Marijana Petrovic,
  • Momir Stevanovic,
  • Dragica Selakovic and
  • Gvozden Rosic

The aim of this study was to evaluate the interradicular septum bone morphometric characteristics using cone beam computed tomography (CBCT) images, as well as to establish quantitative shortcuts to allow clinicians to make a faster and more reliable...

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Diagnostics - ISSN 2075-4418