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Life, Volume 12, Issue 6

2022 June - 153 articles

Cover Story: The assessment of shoulder kinematics and kinetics is commonly undertaken using rigid-body models and stereophotogrammetric measurements of skin-mounted marker trajectories. This paper uses a Monte Carlo approach to quantify the effect of the inter-operator uncertainty on the skin marker position as well as the artifact movement between the skin and the underlying bones occurring during exercise on shoulder kinematics and kinetics calculations. Our results reported that computed kinetics is four times more sensitive to marker errors than kinematics. Moreover, to limit shoulder kinematic and kinetic errors, one should prioritize reducing skin artifacts as they contribute to twice as much error as marker misplacements do. View this paper
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Articles (153)

  • Review
  • Open Access
33 Citations
6,006 Views
16 Pages

Production and Characterization of a Bioemulsifier Derived from Microorganisms with Potential Application in the Food Industry

  • Jaffar Z. Thraeib,
  • Ammar B. Altemimi,
  • Alaa Jabbar Abd Al-Manhel,
  • Tarek Gamal Abedelmaksoud,
  • Ahmed Ali Abd El-Maksoud,
  • Chandu S. Madankar and
  • Francesco Cacciola

20 June 2022

There is a growing interest in the development and use of natural emulsifiers, which provide biodegradability as well as non-toxicity along with giving better performance compared to existing emulsifying agents used in the food industry. A large vari...

  • Article
  • Open Access
6 Citations
3,384 Views
8 Pages

Comparison of the C-Reactive Protein Level and Visual Analog Scale Scores between Piezosurgery and Rotatory Osteotomy in Mandibular Impacted Third Molar Extraction

  • Lakshmi Shetty,
  • Khushal Gangwani,
  • Uday Londhe,
  • Swati Bharadwaj,
  • Mohammed Mousa H. Bakri,
  • Ahmed Alamoudi,
  • Rodolfo Reda,
  • Shilpa Bhandi,
  • A. Thirumal Raj and
  • Luca Testarelli
  • + 1 author

20 June 2022

This study aimed to compare the C-reactive protein level and visual analog scale scores of piezo- and rotatory-based surgical extraction of the third molar. As a split-mouth study, the comparative groups consisted of 25 patients, each of whom underwe...

  • Article
  • Open Access
5 Citations
2,881 Views
12 Pages

Effect of Malignancy on Semen Parameters

  • Guy Shrem,
  • Liat Azani,
  • Ido Feferkorn,
  • Tamar Listovsky,
  • Sofia Hussaini,
  • Benjamin Farber,
  • Michael H. Dahan and
  • Mali Salmon-Divon

20 June 2022

Purpose: We aimed to examine how various types of cancer, classified histologically, affect semen quality. Methods: The study group included 313 patients who were diagnosed with cancer and reached for a sperm cryopreservation before a gonadotoxic tre...

  • Article
  • Open Access
8 Citations
3,541 Views
19 Pages

20 June 2022

Upland cotton (Gossypium hirsutum) is a salt-tolerant crop that can withstand high salinity levels without showing signs of harm to the plant. However, the plant is more prone to salinity stress at the germination stage and a poor germination as well...

  • Article
  • Open Access
10 Citations
2,948 Views
14 Pages

Suilyin Disrupts the Blood–Brain Barrier by Activating Group III Secretory Phospholipase A2

  • Yutong Sui,
  • Ying Chen,
  • Qingyu Lv,
  • Yuling Zheng,
  • Decong Kong,
  • Hua Jiang,
  • Wenhua Huang,
  • Yuhao Ren,
  • Peng Liu and
  • Yongqiang Jiang

20 June 2022

Serious diseases caused by Streptococcus suis serotype 2 (S. suis 2) include septicaemia and meningitis, which are associated with high morbidity and mortality. Proliferation in the blood can result in a breach of the blood–brain barrier (BBB)...

  • Article
  • Open Access
3 Citations
4,155 Views
16 Pages

First Steps towards the Development of Epigenetic Biomarkers in Female Cheetahs (Acinonyx jubatus)

  • Alexandra Weyrich,
  • Tania P. Guerrero-Altamirano,
  • Selma Yasar,
  • Gábor Á. Czirják,
  • Bettina Wachter and
  • Jörns Fickel

20 June 2022

Free-ranging cheetahs (Acinonyx jubatus) are generally healthy, whereas cheetahs under human care, such as those in zoological gardens, suffer from ill-defined infectious and degenerative pathologies. These differences are only partially explained by...

  • Article
  • Open Access
4 Citations
5,177 Views
10 Pages

19 June 2022

Background: The aim of the study was to evaluate the effectiveness of subjective tinnitus treatment in patients with cochlear sensorineural hearing loss with magnetic ear stimulation using a prototype device. Since the 1970s, studies have been conduc...

  • Review
  • Open Access
55 Citations
9,411 Views
31 Pages

18 June 2022

Antarctica represents a unique environment, both due to the extreme meteorological and geological conditions that govern it and the relative isolation from human influences that have kept its environment largely undisturbed. However, recent trends in...

  • Article
  • Open Access
2 Citations
3,940 Views
18 Pages

Efficacy of Ficus sycomorus (Sycamore Fig) Extract on Intestinal Coccidiosis in Experimentally Infected Rabbits

  • Ahmed Dawod,
  • Said Fathalla,
  • Hesham R. El-Seedi,
  • Mohamed A. Hammad,
  • Noha Osman,
  • Nagwa Abosheriba,
  • Anis Anis,
  • Awad A. Shehata and
  • Ahmed Elkhatam

18 June 2022

This study was conducted to investigate the effect of the Ficus sycomorus extract on Eimeria intestinalis in experimentally infected rabbits. For this purpose, forty male 30-day-old rabbits (Blanc de Bouscat) were divided into four groups (n = 10 in...

  • Article
  • Open Access
9 Citations
3,200 Views
12 Pages

Effects of Heat Stress and Exogenous Salicylic Acid on Secondary Metabolites Biosynthesis in Pleurotus ostreatus (Jacq.) P. Kumm

  • Yanru Hu,
  • Qianqian Chai,
  • Yue Wang,
  • Yujie Chen,
  • Haozhe Dong,
  • Jinwen Shen,
  • Yuancheng Qi,
  • Haiyou Yu,
  • Fengqin Wang and
  • Qing Wen

17 June 2022

Pleurotus ostreatus (Jacq.) P. Kumm has high medicinal value, but few studies exist on regulating secondary metabolite biosynthesis. Environmental factors play a substantial role in the accumulation of microbial secondary metabolites. In this study,...

  • Article
  • Open Access
24 Citations
6,890 Views
21 Pages

Licorice Extract Supplementation Affects Antioxidant Activity, Growth-Related Genes, Lipid Metabolism, and Immune Markers in Broiler Chickens

  • Magda I. Abo-Samaha,
  • Youssef S. Alghamdi,
  • Set A. El-Shobokshy,
  • Sarah Albogami,
  • Eman M. Abd El-Maksoud,
  • Foad Farrag,
  • Mohamed M. Soliman,
  • Mustafa Shukry and
  • Mohamed E. Abd El-Hack

17 June 2022

The objective of this study was to evaluate the Glycyrrhiza glabra effect on growth performance, blood parameters, antioxidant and lysosomal activity, histology and immunohistochemistry of liver and intestine, and the gene expression profile of broil...

  • Review
  • Open Access
13 Citations
3,860 Views
22 Pages

17 June 2022

The use of digital care visits has been increasing during the COVID-19 pandemic. Learning more about healthcare professionals’ technology experiences provides valuable insight and a basis for improving digital visits. This study aimed to explor...

  • Review
  • Open Access
6 Citations
8,056 Views
10 Pages

Very-Low-Dose Radiation and Clinical Molecular Nuclear Medicine

  • Chi-Jung Tsai,
  • Kang-Wei Chang,
  • Bang-Hung Yang,
  • Ping-Hsiu Wu,
  • Ko-Han Lin,
  • Ching Yee Oliver Wong,
  • Hsin-Lun Lee and
  • Wen-Sheng Huang

17 June 2022

Emerging molecular and precision medicine makes nuclear medicine a de facto choice of imaging, especially in the era of target-oriented medical care. Nuclear medicine is minimally invasive, four-dimensional (space and time or dynamic space), and func...

  • Article
  • Open Access
7 Citations
4,872 Views
14 Pages

Arthrospira platensis Mutagenesis for Protein and C-Phycocyanin Improvement and Proteomics Approaches

  • Wanida Pan-utai,
  • Siriluck Iamtham,
  • Sittiruk Roytrakul,
  • Sarn Settachaimongkon,
  • Ladda Sangduean Wattanasiritham,
  • Sumitra Boonbumrung,
  • Juta Mookdasanit and
  • Sayamon Sithtisarn

17 June 2022

Arthrospira (Spirulina) platensis is known for its use as a food supplement, with reported therapeutic properties including antiviral, anti-inflammatory and antioxidant activity. Arthrospira is also an excellent source of proteins and C-phycocyanin....

  • Review
  • Open Access
48 Citations
9,133 Views
24 Pages

Crosstalk of Astrocytes and Other Cells during Ischemic Stroke

  • Tingting He,
  • Guo-Yuan Yang and
  • Zhijun Zhang

17 June 2022

Stroke is a leading cause of death and long-term disability worldwide. Astrocytes structurally compose tripartite synapses, blood–brain barrier, and the neurovascular unit and perform multiple functions through cell-to-cell signaling of neurons...

  • Case Report
  • Open Access
6 Citations
8,833 Views
9 Pages

An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach

  • Maurizio Guastalegname,
  • Valeria Rondinone,
  • Giuseppe Lucifora,
  • Alfredo Vallone,
  • Laura D’Argenio,
  • Giovanni Petracca,
  • Antonia Giordano,
  • Luigina Serrecchia,
  • Viviana Manzulli and
  • Domenico Galante
  • + 4 authors

17 June 2022

In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were hospit...

  • Review
  • Open Access
11 Citations
6,577 Views
19 Pages

17 June 2022

(1) Background: This study aimed to perform a literature review related to disk displacement (DD) in class II malocclusion or cervical vertebrae position alterations and to report a hypodivergent case with cervical pain and right anterolateral DD wit...

  • Article
  • Open Access
3 Citations
3,037 Views
13 Pages

Heavy-Ion-Induced Lung Tumors: Dose- & LET-Dependence

  • Polly Y. Chang,
  • James Bakke,
  • Chris J. Rosen,
  • Kathleen A. Bjornstad,
  • Jian-Hua Mao and
  • Eleanor A. Blakely

17 June 2022

There is a limited published literature reporting dose-dependent data for in vivo tumorigenesis prevalence in different organs of various rodent models after exposure to low, single doses of charged particle beams. The goal of this study is to reduce...

  • Systematic Review
  • Open Access
4 Citations
4,518 Views
14 Pages

17 June 2022

Background: Maternal obesity is associated with several adverse reproductive outcomes. It is a growing public health burden in sub-Saharan Africa, a region with low resources and capacity to care for the large, affected population. Objectives: To ass...

  • Article
  • Open Access
15 Citations
3,588 Views
8 Pages

17 June 2022

The hydrolate byproduct resulting from the industrial essential oil extraction of Spanish purple garlic has been studied against the root-knot nematode Meloidogyne javanica by in vitro and in vivo bioassays. The essential oil, the hydrolate and its o...

  • Editorial
  • Open Access
1 Citations
2,378 Views
2 Pages

16 June 2022

Although it was discovered about 25 years ago, alpha-synuclein (αS) misfolding and accumulation in neuronal tissues is still recognized as one of the most crucial aspects in Parkinson’s disease (PD) pathology [...]

  • Review
  • Open Access
85 Citations
9,437 Views
28 Pages

Bone Tissue Engineering through 3D Bioprinting of Bioceramic Scaffolds: A Review and Update

  • Ahmad Taha Khalaf,
  • Yuanyuan Wei,
  • Jun Wan,
  • Jiang Zhu,
  • Yu Peng,
  • Samiah Yasmin Abdul Kadir,
  • Jamaludin Zainol,
  • Zahraa Oglah,
  • Lijia Cheng and
  • Zheng Shi

16 June 2022

Trauma and bone loss from infections, tumors, and congenital diseases make bone repair and regeneration the greatest challenges in orthopedic, craniofacial, and plastic surgeries. The shortage of donors, intrinsic limitations, and complications in tr...

  • Article
  • Open Access
2 Citations
3,061 Views
9 Pages

Complex Aortic Interventions Can Be Safely Introduced to the Clinical Practice by Physicians Skilled in Basic Endovascular Techniques

  • Sarolta Borzsák,
  • András Szentiványi,
  • András Süvegh,
  • Daniele Mariastefano Fontanini,
  • Milán Vecsey-Nagy,
  • Péter Banga,
  • Zoltán Szeberin,
  • Péter Sótonyi and
  • Csaba Csobay-Novák

16 June 2022

Our purpose was to evaluate the risk associated with the learning curve of starting a complex aortic programme in an Eastern European country. A retrospective study was conducted involving the initial 20 patients (16 males, mean age: 65 ± 11 y...

  • Article
  • Open Access
24 Citations
4,641 Views
13 Pages

Self-Reported Long COVID in the General Population: Sociodemographic and Health Correlates in a Cross-National Sample

  • Tore Bonsaksen,
  • Janni Leung,
  • Daicia Price,
  • Mary Ruffolo,
  • Gary Lamph,
  • Isaac Kabelenga,
  • Hilde Thygesen and
  • Amy Østertun Geirdal

15 June 2022

We aimed to gain knowledge of possible sociodemographic predictors of long COVID and whether long COVID was associated with health outcomes almost two years after the pandemic outbreak. There were 1649 adults who participated in the study by completi...

  • Article
  • Open Access
20 Citations
3,394 Views
11 Pages

Transbronchial Cryobiopsy Compared to Forceps Biopsy for Diagnosis of Acute Cellular Rejection in Lung Transplants: Analysis of 63 Consecutive Procedures

  • Carolin Steinack,
  • Ariana Gaspert,
  • Fiorenza Gautschi,
  • René Hage,
  • Bart Vrugt,
  • Alex Soltermann,
  • Macé Matthew Schuurmans and
  • Daniel Franzen

15 June 2022

Background: Acute cellular rejection (ACR) is a complication after lung transplantation (LTx). The diagnosis of ACR is based on histologic findings using transbronchial forceps biopsy (FB). However, its diagnostic accuracy is limited because of the s...

  • Article
  • Open Access
13 Citations
3,249 Views
10 Pages

Evaluation of the Effect of Wheat Germ Oil and Olmutinib on the Thioacetamide-Induced Liver and Kidney Toxicity in Mice

  • Salman Alamery,
  • Seema Zargar,
  • Fatimah Yaseen,
  • Tanveer A. Wani and
  • Abdulaziz Siyal

15 June 2022

Thioacetamide (TAA) intoxication produces a reproducible standard animal model of induced liver and kidney injuries where free radicals are produced by phase I oxidation reactions, which eventually leads to liver and kidney failure. Wheat germ oil (W...

  • Article
  • Open Access
4 Citations
10,657 Views
13 Pages

Anti-Inflammatory, Antioxidant, and Anti-Atherosclerotic Effects of Natural Supplements on Patients with FMF-Related AA Amyloidosis: A Non-Randomized 24-Week Open-Label Interventional Study

  • Micol Romano,
  • Facundo Garcia-Bournissen,
  • David Piskin,
  • Ulkumen Rodoplu,
  • Lizzy Piskin,
  • Abdelbaset A. Elzagallaai,
  • Tunc Tuncer,
  • Siren Sezer,
  • Didar Ucuncuoglu and
  • Erkan Demirkaya
  • + 5 authors

15 June 2022

We aimed to evaluate the effect of a combination of natural products on parameters related to inflammation, endothelial dysfunction, and oxidative stress in a cohort of familial Mediterranean fever (FMF) patients with Serum Amyloid A amyloidosis, in...

  • Article
  • Open Access
6 Citations
3,269 Views
15 Pages

In Vitro Characterization of the Human Skeletal Stem Cell-like Properties of Primary Bone-Derived Mesenchymal Stem/Stromal Cells in Patients with Late and Early Hip Osteoarthritis

  • Lara Jasenc,
  • Klemen Stražar,
  • Anže Mihelič,
  • Rene Mihalič,
  • Rihard Trebše,
  • Gregor Haring,
  • Matjaž Jeras and
  • Janja Zupan

15 June 2022

Human skeletal stem cells (hSSCs) were recently identified as podoplanin (PDPN)/CD73/CD164-positive and CD146-negative cells that decline with age, and play a role in the pathogenesis of osteoarthritis (OA). The aim of this study was to identify the...

  • Review
  • Open Access
107 Citations
10,927 Views
20 Pages

Multidrug Resistance of Cancer Cells and the Vital Role of P-Glycoprotein

  • Chenmala Karthika,
  • Raman Sureshkumar,
  • Mehrukh Zehravi,
  • Rokeya Akter,
  • Faraat Ali,
  • Sarker Ramproshad,
  • Banani Mondal,
  • Priti Tagde,
  • Zubair Ahmed and
  • Simona Cavalu
  • + 2 authors

15 June 2022

P-glycoprotein (P-gp) is a major factor in the multidrug resistance phenotype in cancer cells. P-gp is a protein that regulates the ATP-dependent efflux of a wide range of anticancer medicines and confers resistance. Due to its wide specificity, seve...

  • Communication
  • Open Access
19 Citations
3,787 Views
11 Pages

Influence of Different Light-Emitting Diode Colors on Growth and Phycobiliprotein Generation of Arthrospira platensis

  • Conrad H. G. Jung,
  • Peter Waldeck,
  • Shadi Sykora,
  • Steffen Braune,
  • Ingolf Petrick,
  • Jan-Heiner Küpper and
  • Friedrich Jung

15 June 2022

Light-emitting diodes (LED) can be utilized as tailorable artificial light sources for the cultivation of cyanobacteria such as Arthrospira platensis (AP). To study the influence of different LED light colors on phototrophic growth and biomass compos...

  • Article
  • Open Access
10 Citations
3,386 Views
10 Pages

α-Synuclein A53T Promotes Mitochondrial Proton Gradient Dissipation and Depletion of the Organelle Respiratory Reserve in a Neuroblastoma Cell Line

  • Pierpaolo Risiglione,
  • Salvatore Antonio Maria Cubisino,
  • Cristiana Lucia Rita Lipari,
  • Vito De Pinto,
  • Angela Messina and
  • Andrea Magrì

15 June 2022

α-synuclein (αSyn) is a small neuronal protein whose accumulation correlates with Parkinson’s disease. αSyn A53T mutant impairs mitochondrial functions by affecting substrate import within the organelle, activity of complex I...

  • Article
  • Open Access
146 Citations
7,822 Views
12 Pages

Green Biosynthesis of Selenium Nanoparticles Using Orange Peel Waste: Characterization, Antibacterial and Antibiofilm Activities against Multidrug-Resistant Bacteria

  • Salem S. Salem,
  • Mona Shaban E. M. Badawy,
  • Abdulaziz A. Al-Askar,
  • Amr Abker Arishi,
  • Fathy M. Elkady and
  • Amr H. Hashem

15 June 2022

There is an increase of pathogenic multidrug-resistant bacteria globally due to the misuse of antibiotics. Recently, more scientists used metal nanoparticles to counteract antibacterial resistance. In this study, orange peel waste (OPW) was used for...

  • Article
  • Open Access
7 Citations
3,544 Views
10 Pages

Obstetrical and Fertility Outcomes Following Transcatheter Pelvic Arterial Embolization for Postpartum Hemorrhage: A Cohort Follow-Up Study

  • Anda-Petronela Radan,
  • Sophie Schneider,
  • Jarmila A. Zdanowicz,
  • Luigi Raio,
  • Nando Mertineit,
  • Johannes Thomas Heverhagen and
  • Daniel V. Surbek

15 June 2022

Objectives: Management of severe postpartum hemorrhage (PPH) includes transcatheter pelvic arterial embolization (TAE). Data regarding subsequent fertility and obstetrical outcomes is limited, as most fertility outcomes derive from TAE in uterine fib...

  • Editorial
  • Open Access
4 Citations
2,279 Views
2 Pages

15 June 2022

Chronic inflammation has a crucial pathogenetic role in many diseases, including cutaneous chronic inflammatory disorders, such as psoriasis, atopic dermatitis, hidradenitis suppurativa, and chronic urticaria [...]

  • Article
  • Open Access
12 Citations
4,279 Views
13 Pages

14 June 2022

Polycystic ovary syndrome (PCOS) is a complex reproductive, metabolic, and endocrine disorder that affects women of reproductive age. Kelulut honey is stingless bee honey that possesses anti-inflammatory, anti-cancer, anti-diabetic, and potent antiox...

  • Article
  • Open Access
1 Citations
2,227 Views
12 Pages

Hypofractionation and Concomitant Boost in Ductal Carcinoma In Situ (DCIS): Analysis of a Prospective Case Series with Long-Term Follow-Up

  • Domenico Cante,
  • Marina Paolini,
  • Cristina Piva,
  • Edoardo Petrucci,
  • Lorenzo Radici,
  • Silvia Ferrario,
  • Guido Mondini,
  • Silvia Bagnera,
  • Maria Rosa La Porta and
  • Pierfrancesco Franco

14 June 2022

We previously reported on a cohort of breast cancer patients affected with ductal carcinoma in situ (DCIS) that were treated with breast conservative surgery and hypofractionated whole-breast radiotherapy with a concomitant boost to the lumpectomy ca...

  • Article
  • Open Access
44 Citations
5,089 Views
18 Pages

14 June 2022

A biofloc technology-based 75-day indoor growth trial in an 80 L glass aquaria was conducted to evaluate the effects of two different carbon sources (sugarcane bagasse, SB, and wheat flour, WF) on the biofloc composition, bacterial abundance, and gro...

  • Article
  • Open Access
3 Citations
3,185 Views
16 Pages

Differences and Similarities between the Lung Transcriptomic Profiles of COVID-19, COPD, and IPF Patients: A Meta-Analysis Study of Pathophysiological Signaling Pathways

  • Daniel Aguilar,
  • Adelaida Bosacoma,
  • Isabel Blanco,
  • Olga Tura-Ceide,
  • Anna Serrano-Mollar,
  • Joan Albert Barberà and
  • Victor Ivo Peinado

14 June 2022

Coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease associated with high morbidity and mortality. Although many patients recover, long-term sequelae after infection have become increasingly recognized and concerning. Among other seq...

  • Review
  • Open Access
120 Citations
6,844 Views
25 Pages

Salicylic Acid, a Multifaceted Hormone, Combats Abiotic Stresses in Plants

  • Junli Liu,
  • Gaoyang Qiu,
  • Chen Liu,
  • Hua Li,
  • Xiaodong Chen,
  • Qinglin Fu,
  • Yicheng Lin and
  • Bin Guo

14 June 2022

In recent decades, many new and exciting findings have paved the way to the better understanding of plant responses in various environmental changes. Some major areas are focused on role of phytohormone during abiotic stresses. Salicylic acid (SA) is...

  • Review
  • Open Access
16 Citations
5,066 Views
12 Pages

cAMP Is a Promising Regulatory Molecule for Plant Adaptation to Heat Stress

  • Shuang Liang,
  • Jinfeng Sun,
  • Yanmin Luo,
  • Shanshan Lv,
  • Jiajia Chen,
  • Yanpei Liu and
  • Xiuli Hu

14 June 2022

With gradual warming or increased frequency and magnitude of high temperature, heat stress adversely affects plant growth and eventually reduces plant productivity and quality. Plants have evolved complex mechanisms to sense and respond to heat stres...

  • Article
  • Open Access
6 Citations
2,599 Views
11 Pages

Locomotor Activity of Ixodes ricinus Females in 900 MHz Electromagnetic Field

  • Blažena Vargová,
  • Igor Majláth,
  • Juraj Kurimský,
  • Roman Cimbala,
  • Ján Zbojovský,
  • Piotr Tryjanowski and
  • Viktoria Majláthová

13 June 2022

Mobile telecommunications technologies have become an indispensable part of people’s lives of all ages around the world. They affect personal life and social interactions and are a work tool in the work routine. Network availability requirement...

  • Review
  • Open Access
8 Citations
5,204 Views
12 Pages

13 June 2022

Sudden infant death syndrome (SIDS) is defined as the sudden death of an infant younger than one year of age which remains unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, a...

  • Systematic Review
  • Open Access
36 Citations
26,130 Views
18 Pages

13 June 2022

The present study aims to determine the potential benefits of PNF on balance and gait function in patients with chronic stroke by using a systematic review and meta-analysis. Systematic review in the following databases: MEDLINE/PubMed, Physiotherapy...

  • Case Report
  • Open Access
3 Citations
2,755 Views
7 Pages

13 June 2022

Background: Panfolliculoma (PF) is a relative rare, benign follicular tumor comprised of all elements of the hair follicle, with a limited number of cases reported in the literature. Articles on the demographic and pathological analysis of this tumor...

  • Review
  • Open Access
10 Citations
4,680 Views
22 Pages

Cancer Cachexia and Antitumor Immunity: Common Mediators and Potential Targets for New Therapies

  • Konstantinos Rounis,
  • Dimitrios Makrakis,
  • Ioannis Gioulbasanis,
  • Simon Ekman,
  • Luigi De Petris,
  • Dimitris Mavroudis and
  • Sofia Agelaki

12 June 2022

Cancer cachexia syndrome (CCS) is a multifactorial metabolic syndrome affecting a significant proportion of patients. CCS is characterized by progressive weight loss, alterations of body composition and a systemic inflammatory status, which exerts a...

  • Article
  • Open Access
2 Citations
2,633 Views
14 Pages

12 June 2022

Children with diabetes, and particularly those with obesity, have poor glycemic control. They are thus at higher risk of early microvascular complications. Renal tubulointerstitial markers are integral to evaluating diabetic nephropathy. Various biom...

  • Article
  • Open Access
6 Citations
2,690 Views
15 Pages

Chromatographic Profile and Redox-Modulating Capacity of Methanol Extract from Seeds of Ginkgo biloba L. Originating from Plovdiv Region in Bulgaria

  • Lubomir Petrov,
  • Albena Alexandrova,
  • Mariana Argirova,
  • Teodora Tomova,
  • Almira Georgieva,
  • Elina Tsvetanova and
  • Milka Mileva

12 June 2022

Oxidative stress underlies the pathogenesis of many diseases, which determines the interest in natural substances with antioxidant properties. Ginkgo biloba L. leaves are well known and widely used in the pharmaceutical industry, but the therapeutic...

  • Article
  • Open Access
5 Citations
4,183 Views
28 Pages

Characterization of Aurintricarboxylic Acid (ATA) Interactions with Plasma Transporter Protein and SARS-CoV-2 Viral Targets: Correlation of Functional Activity and Binding Energetics

  • Conceição A. Minetti,
  • David P. Remeta,
  • Keiji Hashimoto,
  • Radha Bonala,
  • Rajesh Chennamshetti,
  • Xingyu Yin,
  • Miguel Garcia-Diaz,
  • Arthur P. Grollman,
  • Francis Johnson and
  • Viktoriya S. Sidorenko

10 June 2022

In an effort to identify functional-energetic correlations leading to the development of efficient anti-SARS-CoV-2 therapeutic agents, we have designed synthetic analogs of aurintricarboxylic acid (ATA), a heterogeneous polymeric mixture of structura...

  • Article
  • Open Access
3 Citations
2,633 Views
16 Pages

10 June 2022

The 4D-Dynamic Representation of DNA/RNA Sequences, an alignment-free bioinformatics method recently developed by us, has been used to study the genetic diversity of Echinococcus multilocularis in red foxes in Poland. Sequences of three mitochondrial...

  • Article
  • Open Access
5 Citations
3,643 Views
16 Pages

2-(3-Bromophenyl)-8-fluoroquinazoline-4-carboxylic Acid as a Novel and Selective Aurora A Kinase Inhibitory Lead with Apoptosis Properties: Design, Synthesis, In Vitro and In Silico Biological Evaluation

  • Mohamed H. Elsherbeny,
  • Usama M. Ammar,
  • Magda H. Abdellattif,
  • Mohammed A. S. Abourehab,
  • Ahmed Abdeen,
  • Samah F. Ibrahim,
  • Doaa Abdelrahaman,
  • Wessam Mady,
  • Eun Joo Roh and
  • Ahmed Elkamhawy

10 June 2022

New quinazoline derivatives were designed based on the structural modification of the reported inhibitors to enhance their selectivity toward Aurora A. The synthesized compounds were tested over Aurora A, and a cytotoxicity assay was performed over N...

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Life - ISSN 2075-1729