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Micromachines, Volume 9, Issue 7

2018 July - 54 articles

Cover Story: Circulating biomarkers (CBs) such as exosome and cell-free DNA (cfDNA) are present in saliva and reflect the cancer status of patients. The salivary CBs can be obtained non-invasively using simple collecting methods like swab sucking. However, since the concentration of CBs in saliva is lower than that in blood, it is important to enrich CBs before analysis. Microfluidic technology is a promising tool for integrating saliva pretreatment, enrichment and detection of CBs on a single chip at high throughput sensitivity. By analyzing salivary CBs through microfluidic platform, clinical cancer research may progress more rapidly and efficiently. View this paper.
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Articles (54)

  • Article
  • Open Access
5 Citations
4,460 Views
21 Pages

23 July 2018

Magnetically actuated microrobot in a liquid media is faced with the problem of head-tilting reaction caused by its hydrodynamic structure and its speed while moving horizontally. When the instance microrobot starts a lateral motion, the drag force a...

  • Article
  • Open Access
4 Citations
5,739 Views
11 Pages

Poly(ionic liquid)s Based Brush Type Nanomotor

  • Yongjun Men,
  • Yingfeng Tu,
  • Wei Li,
  • Fei Peng and
  • Daniela A. Wilson

23 July 2018

A brush type nanomotor was fabricated via assembly assistant polymerization of poly(ionic liquid) and surface grafting polymerization. The method for large-scale fabrication of brush nanomotors with soft surfaces is described. These soft locomotive p...

  • Article
  • Open Access
5 Citations
4,814 Views
12 Pages

Micro Motion Amplifiers for Compact Out-of-Plane Actuation

  • Xin Xie,
  • Majid Bigdeli Karimi,
  • Sanwei Liu,
  • Battushig Myanganbayar and
  • Carol Livermore

23 July 2018

Small-scale, out-of-plane actuators can enable tactile interfaces; however, achieving sufficient actuator force and displacement can require larger actuators. In this work, 2-mm2 out-of-plane microactuators were created, and were demonstrated to outp...

  • Feature Paper
  • Article
  • Open Access
19 Citations
5,277 Views
13 Pages

Long Period Grating-Based Fiber Coupling to WGM Microresonators

  • Francesco Chiavaioli,
  • Dario Laneve,
  • Daniele Farnesi,
  • Mario Christian Falconi,
  • Gualtiero Nunzi Conti,
  • Francesco Baldini and
  • Francesco Prudenzano

23 July 2018

A comprehensive model for designing robust all-in-fiber microresonator-based optical sensing setups is illustrated. The investigated all-in-fiber setups allow light to selectively excite high-Q whispering gallery modes (WGMs) into optical microresona...

  • Article
  • Open Access
11 Citations
3,895 Views
12 Pages

22 July 2018

This paper presents for the first time an improved algorithm for vibration amplitude-phase information extraction of capacitive microelectromechanical systems (MEMS) gyroscopes. Amplitude and phase information resulting from the improved algorithm is...

  • Review
  • Open Access
31 Citations
6,927 Views
20 Pages

21 July 2018

In this article, a new conceptual biomedical engineering strategy to tackle modern disease challenges, called liquid metal (LM) enabled electrobiology, is proposed. This generalized and simple method is based on the physiological fact that specially...

  • Review
  • Open Access
157 Citations
15,314 Views
23 Pages

Topic Review: Application of Raman Spectroscopy Characterization in Micro/Nano-Machining

  • Zongwei Xu,
  • Zhongdu He,
  • Ying Song,
  • Xiu Fu,
  • Mathias Rommel,
  • Xichun Luo,
  • Alexander Hartmaier,
  • Junjie Zhang and
  • Fengzhou Fang

21 July 2018

The defects and subsurface damages induced by crystal growth and micro/nano-machining have a significant impact on the functional performance of machined products. Raman spectroscopy is an efficient, powerful, and non-destructive testing method to ch...

  • Article
  • Open Access
24 Citations
5,196 Views
12 Pages

20 July 2018

During rolling stock operation, various kinds of energy such as vibration, heat, and train-induced wind are dissipated. The amount of energy dissipation cannot be overlooked when a heavy railroad vehicle operates at high speed. Therefore, if the wast...

  • Review
  • Open Access
14 Citations
6,002 Views
22 Pages

Compound Glass Microsphere Resonator Devices

  • Jibo Yu,
  • Elfed Lewis,
  • Gerald Farrell and
  • Pengfei Wang

19 July 2018

In recent years, compound glass microsphere resonator devices have attracted increasing interest and have been widely used in sensing, microsphere lasers, and nonlinear optics. Compared with traditional silica resonators, compound glass microsphere r...

  • Article
  • Open Access
10 Citations
3,660 Views
9 Pages

A Study on Microturning with Electrochemical Assistance of the Cutting Process

  • Marcin Grabowski,
  • Sebastian Skoczypiec and
  • Dominik Wyszynski

19 July 2018

The paper investigated an electrochemically-assisted microturning process. Depending on the variant of electrochemical assistance, material can be removed with simultaneous electrochemical and mechanical action or electrochemical assistance can chang...

  • Article
  • Open Access
4 Citations
4,229 Views
11 Pages

19 July 2018

In this paper, a polydimethylsiloxane (PDMS) fabrication method is introduced. It eliminates the need for conventional fabrication methods, such as photolithography and etching. Only a series of oxygen plasma treatments, silanization, and polyvinyl c...

  • Feature Paper
  • Article
  • Open Access
20 Citations
6,978 Views
14 Pages

Injection Compression Molded Microlens Arrays for Hyperspectral Imaging

  • Marcel Roeder,
  • Marc Drexler,
  • Thilo Rothermel,
  • Thomas Meissner,
  • Thomas Guenther and
  • André Zimmermann

18 July 2018

In this work, a polymer microlens array (MLA) for a hyperspectral imaging (HSI) system is produced by means of ultraprecision milling (UP-milling) and injection compression molding. Due to the large number of over 12,000 microlenses on less than 2 cm...

  • Article
  • Open Access
16 Citations
4,102 Views
7 Pages

16 July 2018

The accurate detection of NOx is an important issue, because nitrogen oxides are not only environmental pollutants, but also harm to human health. An array composed of two carbon nanotubes (CNTs)-based ionization sensors with different separations is...

  • Article
  • Open Access
29 Citations
7,850 Views
17 Pages

Updated Tactile Feedback with a Pin Array Matrix Helps Blind People to Reduce Self-Location Errors

  • Luca Brayda,
  • Fabrizio Leo,
  • Caterina Baccelliere,
  • Elisabetta Ferrari and
  • Claudia Vigini

14 July 2018

Autonomous navigation in novel environments still represents a challenge for people with visual impairment (VI). Pin array matrices (PAM) are an effective way to display spatial information to VI people in educative/rehabilitative contexts, as they p...

  • Article
  • Open Access
9 Citations
9,246 Views
15 Pages

Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint

  • Yun-Ting Chen,
  • Kun-Ying Yeh,
  • Szu-Han Chen,
  • Chuang-Yin Wang,
  • Chao-Chi Yeh,
  • Ming-Xin Xu,
  • Shey-Shi Lu,
  • Yunn-Jy Chen and
  • Yao-Joe Yang

14 July 2018

Obstructive sleep apnea (OSA), which is caused by obstructions of the upper airway, is a syndrome with rising prevalence. Mandibular advancement splints (MAS) are oral appliances for potential treatment of OSA. This work proposes a highly-sensitive p...

  • Review
  • Open Access
41 Citations
8,762 Views
21 Pages

Progress in Circulating Tumor Cell Research Using Microfluidic Devices

  • Hogyeong Gwak,
  • Junmoo Kim,
  • Leila Kashefi-Kheyrabadi,
  • Bongseop Kwak,
  • Kyung-A Hyun and
  • Hyo-Il Jung

14 July 2018

Circulating tumor cells (CTCs) are a popular topic in cancer research because they can be obtained by liquid biopsy, a minimally invasive procedure with more sample accessibility than tissue biopsy, to monitor a patient’s condition. Over the pa...

  • Feature Paper
  • Review
  • Open Access
81 Citations
11,379 Views
29 Pages

13 July 2018

Graphene transparent conductive electrodes are highly attractive for photodetector (PD) applications due to their excellent electrical and optical properties. The emergence of graphene/semiconductor hybrid heterostructures provides a platform useful...

  • Article
  • Open Access
13 Citations
4,675 Views
12 Pages

12 July 2018

Process parameter conditions such as vibrating motion, abrasives, pressure and tool wear play an important role in vibration-assisted polishing of micro-optic molds as they strongly affect material removal efficiency and stability. This paper present...

  • Article
  • Open Access
14 Citations
4,984 Views
13 Pages

Improved Virtual Gyroscope Technology Based on the ARMA Model

  • Jinlong Song,
  • Zhiyong Shi,
  • Lvhua Wang and
  • Hailiang Wang

11 July 2018

In view of the large output noise and low precision of the Micro-electro-mechanical Systems (MEMS) gyroscope, the virtual gyroscope technology was used to fuse the data of the MEMS gyroscope to improve its output precision. Random error model in the...

  • Feature Paper
  • Article
  • Open Access
15 Citations
5,641 Views
9 Pages

2D Optical Gratings Based on Hexagonal Voids on Transparent Elastomeric Substrate

  • Valentina Piccolo,
  • Andrea Chiappini,
  • Cristina Armellini,
  • Mario Barozzi,
  • Anna Lukowiak,
  • Pier-John A. Sazio,
  • Alessandro Vaccari,
  • Maurizio Ferrari and
  • Daniele Zonta

10 July 2018

A chromatic vectorial strain sensor constituted by hexagonal voids on transparent elastomeric substrate has been successfully fabricated via soft colloidal lithography. Initially a highly ordered 1.6 microns polystyrene spheres monolayer colloidal cr...

  • Review
  • Open Access
60 Citations
8,617 Views
17 Pages

Recent Progress in Rapid Sintering of Nanosilver for Electronics Applications

  • Wei Liu,
  • Rong An,
  • Chunqing Wang,
  • Zhen Zheng,
  • Yanhong Tian,
  • Ronglin Xu and
  • Zhongtao Wang

10 July 2018

Recently, nanosilver pastes have emerged as one of the most promising high temperature bonding materials for high frequency and high power applications, which provide an effective lead-free electronic packaging solution instead of high-lead and gold-...

  • Article
  • Open Access
8 Citations
6,696 Views
16 Pages

Reconfigurable Sensor Analog Front-End Using Low-Noise Chopper-Stabilized Delta-Sigma Capacitance-to-Digital Converter

  • Hyungseup Kim,
  • Byeoncheol Lee,
  • Yeongjin Mun,
  • Jaesung Kim,
  • Kwonsang Han,
  • Youngtaek Roh,
  • Dongkyu Song,
  • Seounghoon Huh and
  • Hyoungho Ko

10 July 2018

This paper proposes a reconfigurable sensor analog front-end using low-noise chopper-stabilized delta-sigma capacitance-to-digital converter (CDC) for capacitive microsensors. The proposed reconfigurable sensor analog front-end can drive both capacit...

  • Article
  • Open Access
22 Citations
5,042 Views
11 Pages

Frequency Characteristic of Resonant Micro Fluidic Chip for Oil Detection Based on Resistance Parameter

  • Zilei Yu,
  • Lin Zeng,
  • Hongpeng Zhang,
  • Guogang Yang,
  • Wenqi Wang and
  • Wanheng Zhang

Monitoring the working condition of hydraulic equipment is significance in industrial fields. The abnormal wear of the hydraulic system can be revealed by detecting the variety and size of micro metal debris in the hydraulic oil. We thus present the...

  • Article
  • Open Access
3 Citations
5,219 Views
12 Pages

Resonant Directly Coupled Inductors–Capacitors Ladder Network Shows a New, Interesting Property Useful for Application in the Sensor Field, Down to Micrometric Dimensions

  • Arnaldo D’Amico,
  • Marco Santonico,
  • Giorgio Pennazza,
  • Alessandro Zompanti,
  • Emma Scipioni,
  • Giuseppe Ferri,
  • Vincenzo Stornelli,
  • Marcello Salmeri and
  • Roberto Lojacono

The study of ladder networks made by sequences of directly coupled inductor–capacitor single cells has led us to discover a new property, which may be of certain interest in the sensor field. In the case of n cells, the n-frequencies vector cha...

  • Article
  • Open Access
15 Citations
6,253 Views
17 Pages

Current CMOS-micro-electro-mechanical systems (MEMS) fabrication technologies permit cardiological implantable devices with sensing capabilities, such as the iStents, to be developed in such a way that MEMS sensors can be monolithically integrated to...

  • Review
  • Open Access
17 Citations
7,223 Views
21 Pages

Thick SU-8 photoresist has been a popular photoresist material to fabricate various mechanical, biological, and chemical devices for many years. The accuracy and precision of the ultraviolet (UV) lithography process of thick SU-8 depend on key parame...

  • Review
  • Open Access
55 Citations
11,489 Views
13 Pages

Salivary Exosome and Cell-Free DNA for Cancer Detection

  • Kyung-A Hyun,
  • Hogyeong Gwak,
  • Jaehun Lee,
  • Bongseop Kwak and
  • Hyo-Il Jung

Liquid biopsies are easier to acquire patient derived samples than conventional tissue biopsies, and their use enables real-time monitoring of the disease through continuous sampling after initial diagnosis, resulting in a paradigm shift to customize...

  • Article
  • Open Access
64 Citations
4,929 Views
13 Pages

Adaptive Backstepping Design of a Microgyroscope

  • Yunmei Fang,
  • Juntao Fei and
  • Yuzheng Yang

This paper presents a novel algorithm for the design and analysis of an adaptive backstepping controller (ABC) for a microgyroscope. Firstly, Lagrange–Maxwell electromechanical equations are established to derive the dynamic model of a z-axis m...

  • Article
  • Open Access
10 Citations
11,027 Views
18 Pages

The basic rules of self-organization using a totalistic cellular automaton (CA) were investigated, for which the cell state was determined by summing the states of neighboring cells, like in Conway’s Game of Life. This study used a short-range...

  • Article
  • Open Access
3 Citations
4,423 Views
11 Pages

In single cell analysis, transport of foreign substances into a cell is an important technique. In particular, for accurate analysis, a method to transport a small amount (pico-liter order) of substance into the cell without leakage while retaining t...

  • Article
  • Open Access
14 Citations
4,549 Views
19 Pages

Development of Porous Coatings Enriched with Magnesium and Zinc Obtained by DC Plasma Electrolytic Oxidation

  • Krzysztof Rokosz,
  • Tadeusz Hryniewicz,
  • Sofia Gaiaschi,
  • Patrick Chapon,
  • Steinar Raaen,
  • Winfried Malorny,
  • Dalibor Matýsek and
  • Kornel Pietrzak

Coatings with developed surface stereometry, being based on a porous system, may be obtained by plasma electrolytic oxidation, PEO (micro arc oxidation, MAO). In this paper, we present novel porous coatings, which may be used, e.g., in micromachine&r...

  • Article
  • Open Access
15 Citations
5,172 Views
11 Pages

Nowadays, large aspheric surfaces, including non-rotationally symmetric surfaces, are increasingly used in ground- and space-based astronomical instruments. The fabrication of these surfaces with sub-micrometric form accuracy and nanometric surface f...

  • Article
  • Open Access
30 Citations
6,202 Views
15 Pages

In order to enhance the measurement availability for manufacturing applications, on-machine surface measurement (OMSM) is integrated onto the machine tools, which avoids the errors caused by re-positioning workpieces and utilizes the machine axes to...

  • Article
  • Open Access
11 Citations
4,423 Views
12 Pages

Mixed micro- and nanoscale structures are gaining popularity in various fields due to their rapid advances in patterning. An investigation in stamp resist filling with multiscale cavities via ultraviolet (UV) nanoimprint lithography (UV-NIL) is neces...

  • Article
  • Open Access
20 Citations
5,571 Views
8 Pages

Microlens arrays have been widely used in the fields of micro-optics because of the advantages of their high diffraction efficiency, high fill factor, and wide operating band. However, the microlens array still has problems with its smaller field of...

  • Review
  • Open Access
75 Citations
10,242 Views
21 Pages

A Review of the Precision Glass Molding of Chalcogenide Glass (ChG) for Infrared Optics

  • Tianfeng Zhou,
  • Zhanchen Zhu,
  • Xiaohua Liu,
  • Zhiqiang Liang and
  • Xibin Wang

Chalcogenide glass (ChG) is increasingly demanded in infrared optical systems owing to its excellent infrared optical properties. ChG infrared optics including ChG aspherical and freeform optics are mainly fabricated using the single point diamond tu...

  • Article
  • Open Access
3 Citations
3,607 Views
13 Pages

Multi-axis Response of a Thermal Convection-based Accelerometer

  • Jae Keon Kim,
  • Maeum Han,
  • Shin-Won Kang,
  • Seong Ho Kong and
  • Daewoong Jung

29 June 2018

A thermal convection-based accelerometer was fabricated, and its characteristics were analyzed in this study. To understand the thermal convection of the accelerometer, the Grashof and Prandtl number equations were analyzed. This study conducted expe...

  • Article
  • Open Access
31 Citations
8,802 Views
14 Pages

29 June 2018

The needle-type droplet jetting dispenser has wide applications in the field of microelectronic packaging, and for which the good quality of droplet formation and separation is the key to successful dispensing. This paper simulates the droplet jettin...

  • Feature Paper
  • Article
  • Open Access
41 Citations
5,570 Views
12 Pages

3D Printed Microfluidic Features Using Dose Control in X, Y, and Z Dimensions

  • Michael J. Beauchamp,
  • Hua Gong,
  • Adam T. Woolley and
  • Gregory P. Nordin

28 June 2018

Interest has grown in recent years to leverage the possibilities offered by three-dimensional (3D) printing, such as rapid iterative changes; the ability to more fully use 3D device volume; and ease of fabrication, especially as it relates to the cre...

  • Article
  • Open Access
24 Citations
5,557 Views
12 Pages

Engineering of Removing Sacrificial Materials in 3D-Printed Microfluidics

  • Pengju Yin,
  • Bo Hu,
  • Langlang Yi,
  • Chun Xiao,
  • Xu Cao,
  • Lei Zhao and
  • Hongyan Shi

28 June 2018

Three-dimensional (3D) printing will create a revolution in the field of microfluidics due to fabricating truly three-dimensional channels in a single step. During the 3D-printing process, sacrificial materials are usually needed to fulfill channels...

  • Article
  • Open Access
13 Citations
3,994 Views
12 Pages

28 June 2018

This paper proposes an effective method to calibrate the microelectromechanical systems (MEMS) vibratory gyroscope based on the virtual Coriolis force. This method utilizes a series of voltage signals to simulate the Coriolis force input, and the gyr...

  • Article
  • Open Access
11 Citations
3,724 Views
13 Pages

Analysis of Shape Geometry and Roughness of Ti6Al4V Parts Fabricated by Nanosecond Laser Ablation

  • Sabina Luisa Campanelli,
  • Fulvio Lavecchia,
  • Nicola Contuzzi and
  • Gianluca Percoco

27 June 2018

Laser milling is a micro-machining process that uses a laser beam as a tool to remove material through the layer-by-layer ablation mechanism. Generally in laser ablation, the quality of parts is reduced by melt accretions and thermal damage; therefor...

  • Article
  • Open Access
3 Citations
3,936 Views
15 Pages

27 June 2018

In this paper, we develop a new sensor network system with a high sampling rate (over 500 Hz) based on the simultaneous synchronization of clock and data acquisition for integrating the data obtained from various sensors. Hence, we also propose a met...

  • Article
  • Open Access
14 Citations
4,271 Views
13 Pages

Characterization of Cotton Ball-like Au/ZnO Photocatalyst Synthesized in a Micro-Reactor

  • Ki-Joong Kim,
  • Peter B. Kreider,
  • Ho-Geun Ahn and
  • Chih-Hung Chang

26 June 2018

Noble metal/metal oxide nanostructures are an efficient system in photocatalysis. Continuous and scalable production of advanced particle systems will be a requirement for commercial-scale deployment for many applications, including photocatalysis. I...

  • Article
  • Open Access
33 Citations
8,871 Views
20 Pages

26 June 2018

Over the last decade, MEMS microphones have become the leading solution for implementing the audio module in most portable devices. One of the main drivers for the success of the MEMS microphone has been the continuous improvement of the correspondin...

  • Article
  • Open Access
15 Citations
4,676 Views
14 Pages

The Design and Positioning Method of a Flexible Zoom Artificial Compound Eye

  • Lun Li,
  • Yongping Hao,
  • Jiulong Xu,
  • Fengli Liu and
  • Jiang Lu

25 June 2018

The focal lengths of the sub-eyes in a single-layer uniform curved compound eye are all the same, resulting in poor imaging quality for the compound eye. A non-uniform curved compound eye can effectively solve the problem of poor edge-imaging quality...

  • Review
  • Open Access
2,774 Views
14 Pages

25 June 2018

Atom-sized contacts of metals are usually characterized by their direct current (DC) conductance. However, when atom-sized contacts are used as device interconnects and transmit high frequency signals or fast pulses, the most critical parameter is no...

  • Feature Paper
  • Review
  • Open Access
93 Citations
16,120 Views
35 Pages

Recent Advances in Tactile Sensing Technology

  • Minhoon Park,
  • Bo-Gyu Bok,
  • Jong-Hyun Ahn and
  • Min-Seok Kim

25 June 2018

Research on tactile sensing technology has been actively conducted in recent years to pave the way for the next generation of highly intelligent devices. Sophisticated tactile sensing technology has a broad range of potential applications in various...

  • Article
  • Open Access
21 Citations
4,973 Views
17 Pages

24 June 2018

Red blood cell (RBC) aggregation causes to alter hemodynamic behaviors at low flow-rate regions of post-capillary venules. Additionally, it is significantly elevated in inflammatory or pathophysiological conditions. In this study, multiple and period...

  • Article
  • Open Access
14 Citations
5,414 Views
7 Pages

23 June 2018

Considering the isotropic release process of nanoelectromechanical systems (NEMSs), defining the active region of NEM memory switches is one of the most challenging process technologies for the implementation of monolithic-three-dimensional (M3D) CMO...

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Micromachines - ISSN 2072-666X