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Clinics and Practice, Volume 13, Issue 4

2023 August - 24 articles

Cover Story: Oxidative stress is defined as the imbalance between the production of free radicals and their removal by antioxidants, leading to the accumulation and subsequent organ and tissue damage. Glutathione is commonly referred to as the principal antioxidant of the brain and, therefore, plays a critical role in maintaining redox homeostasis. Reduced levels of glutathione in the brain increase its vulnerability to oxidative stress, and may be associated with the development and progression of several psychiatric disorders. We analyze potential associations between the glutathione antioxidant pathway and psychiatric disorders. Our findings further suggest a need to study such pathways with consideration of the interactions with first-line pharmacotherapy, and the potential use of antioxidants as supplemental therapy. View this paper
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Articles (24)

  • Review
  • Open Access
30 Citations
5,466 Views
21 Pages

20 August 2023

The success of artificial intelligence depends on whether it can penetrate the boundaries of evidence-based medicine, the lack of policies, and the resistance of medical professionals to its use. The failure of digital health to meet expectations req...

  • Article
  • Open Access
2 Citations
3,314 Views
17 Pages

The Impact of the Test Dissociation on the Binocular Balance of Children

  • Danjela Ibrahimi,
  • Marcos Aviles and
  • Juvenal Rodríguez-Reséndiz

18 August 2023

Purpose: this research compared the dissociated phoria at near and distance fixation in free space using the Howell test, alternate Cover test, and Thorington test. Methods: 220 healthy Mexican children (mean age 8.3±2.5 years) participated in...

  • Review
  • Open Access
38 Citations
14,208 Views
18 Pages

Overview of Movement Disorders Secondary to Drugs

  • Jamir Pitton Rissardo,
  • Nilofar Vora,
  • Bejoi Mathew,
  • Vikas Kashyap and ,
  • Sara Muhammad and
  • Ana Letícia Fornari Caprara
  • + 1 author+ 0 author

18 August 2023

Drug-induced movement disorders affect a significant percentage of individuals, and they are commonly overlooked and underdiagnosed in clinical practice. Many comorbidities can affect these individuals, making the diagnosis even more challenging. Sev...

  • Review
  • Open Access
5 Citations
3,403 Views
15 Pages

Past, Current, and Future Perspectives on Transplanting Acute Kidney Injury Kidneys

  • Rachana Punukollu,
  • Margaret Ryan,
  • Suman Misra,
  • Pooja Budhiraja and ,
  • Stephanie Ohara,
  • Kayla Kumm,
  • Giselle Guerra,
  • Kunam S. Reddy,
  • Raymond Heilman and
  • Caroline C. Jadlowiec
  • + 5 authors+ 0 author

14 August 2023

(1) Background: Acute kidney injury (AKI) kidneys have high non-utilization rates due to concerns regarding unfavorable outcomes. In this paper, we aimed to review the past, present, and future opinions on AKI kidneys. (2) Methods: A PubMed search wa...

  • Article
  • Open Access
6 Citations
6,012 Views
20 Pages

Guided Superficial Enhanced Fluid Fat Injection (SEFFI) Procedures for Facial Rejuvenation: An Italian Multicenter Retrospective Case Report

  • Alessandro Gennai,
  • Monica Baldessin,
  • Fabrizio Melfa,
  • Bruno Bovani and ,
  • Alessandra Camporese,
  • Barbara Claysset,
  • Mattia Colli,
  • Alberto Diaspro,
  • Rosalba Russo and
  • Piero Tesauro
  • + 12 authors+ 7 authors

8 August 2023

Background: The aging process starts in the center of the face, in the periocular region and around the mouth, with a combination of volume loss, tissue descent, deepened wrinkles, and the loss of skin structure and quality. Recently, several studies...

  • Case Report
  • Open Access
3 Citations
2,287 Views
7 Pages

8 August 2023

Constructive disability poses significant challenges. However, such manifestations are often overlooked. To address these disabilities, customized rehabilitation is necessary across disease stages. This case report demonstrates how customized, stage-...

  • Article
  • Open Access
10 Citations
6,838 Views
16 Pages

2 August 2023

Aim: There needs to be more general agreement on the most effective treatment for the emergency patient with Symptomatic Irreversible Pulpitis (SIP). This equivalence randomised clinical study compared the clinical efficiency, as an urgent treatment,...

(This article belongs to the Special Issue New Trends, Materials, and Technologies and Consolidating Best Practices in Dentistry)
  • Article
  • Open Access
2,488 Views
9 Pages

Camel-Related Facial Injuries: A Seven-Year Retrospective Study

  • Mohamed A. Al-Ali,
  • Hussam M. Mousa,
  • Isabelle Nibelle and
  • Ashraf F. Hefny

1 August 2023

Facial injuries caused by camels can be associated with adverse long-term effects on patients’ quality of life. We aimed to investigate camel-related facial injuries in Al-Ain City, UAE, focusing on their incidence, types, mechanisms, anatomica...

  • Opinion
  • Open Access
7 Citations
4,202 Views
8 Pages

Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression?

  • Harshavardhan Sanekommu,
  • Sobaan Taj,
  • Rida Mah Noor,
  • Muhammad Umair Akmal and ,
  • Reza Akhtar,
  • Mohammad Hossain and
  • Arif Asif
  • + 2 authors+ 0 author

1 August 2023

Chronic kidney disease (CKD) is a global health challenge affecting nearly 700 million people worldwide. In the United States alone, the Medicare costs for CKD management has reached nearly USD 80 billion per year. While reversing CKD may be possible...

  • Article
  • Open Access
12 Citations
7,756 Views
8 Pages

Epidermolysis Bullosa—A Kindler Syndrome Case Report and Short Literature Review

  • Bogdan Ioan Stefanescu,
  • Diana Sabina Radaschin,
  • Geta Mitrea,
  • Lucretia Anghel and ,
  • Adrian Beznea,
  • Georgiana Bianca Constantin and
  • Alin Laurentiu Tatu
  • + 2 authors+ 0 author

30 July 2023

Introduction: Epidermolysis bullosa (EB) represents a group of rare disorders, genetically determined, characterized by skin fragility, blister formation and erosions due to minimal trauma. Depending on the ultrastructural level of skin cleavage, abo...

  • Systematic Review
  • Open Access
6 Citations
3,209 Views
10 Pages

Mobile Health Solutions for Prostate Cancer Diagnostics—A Systematic Review

  • Masood Moghul,
  • Walter Cazzaniga,
  • Fionnuala Croft,
  • Netty Kinsella and ,
  • Declan Cahill and
  • Nicholas David James
  • + 1 author+ 0 author

28 July 2023

Prostate cancer, the most common cause of cancer in men in the UK and one of the most common around the world to date, has no consensus on screening. Multiple large-scale trials from around the world have produced conflicting outcomes in cancer-speci...

  • Article
  • Open Access
30 Citations
3,527 Views
10 Pages

Screening, Genetic Variants, and Bipolar Disorders: Can Useful Hypotheses Arise from the Sum of Partial Failures?

  • Mauro Giovanni Carta,
  • Goce Kalcev,
  • Alessandra Scano,
  • Samantha Pinna and ,
  • Cesar Ivan Aviles Gonzalez,
  • Antonio Egidio Nardi,
  • Germano Orrù and
  • Diego Primavera
  • + 3 authors+ 0 author

27 July 2023

Bipolar disorder (BD) is a relevant public health issue, therefore accurate screening tools could be useful. The objective of this study is to verify the accuracy of the Mood Disorder Questionnaire (MDQ) and genetic risk as screeners, and their compa...

(This article belongs to the Special Issue 2023 Feature Papers in Clinics and Practice)
  • Review
  • Open Access
37 Citations
6,260 Views
15 Pages

The Emerging Role of Senotherapy in Cancer: A Comprehensive Review

  • Sarubala Malayaperumal,
  • Francesco Marotta,
  • Makalakshmi Murali Kumar,
  • Indumathi Somasundaram and ,
  • Antonio Ayala,
  • Mario Munoz Pinto,
  • Antara Banerjee and
  • Surajit Pathak
  • + 3 authors+ 0 author

22 July 2023

Senotherapy, a promising therapeutic strategy, has drawn a lot attention recently due to its potential for combating cancer. Senotherapy refers to the targeting of senescent cells to restore tissue homeostasis and mitigate the deleterious effects ass...

(This article belongs to the Special Issue 2023 Feature Papers in Clinics and Practice)
  • Case Report
  • Open Access
7 Citations
3,753 Views
8 Pages

Myoclonus Secondary to Amantadine: Case Report and Literature Review

  • Jamir Pitton Rissardo and
  • Ana Letícia Fornari Caprara

20 July 2023

The usual adverse events of amantadine are dizziness, dry mouth, and peripheral edema. Postmarketing experience has revealed abnormal movements such as tremors, involuntary muscle contractions, and gait abnormalities. Herein, we report a case of an e...

  • Article
  • Open Access
15 Citations
3,382 Views
10 Pages

Free Tissue Transfer in Head and Neck Reconstruction: A Multidisciplinary 15-Year Experience

  • Athanasios Papanikolaou,
  • Laetitia Guarino,
  • Roland Giger,
  • Benoît Schaller and ,
  • Mihai Constantinescu,
  • Radu Olariu and
  • Ioana Lese
  • + 2 authors+ 0 author

12 July 2023

Background: Free tissue transfer is considered the gold standard in reconstruction of extensive defects in head and neck surgery. The aim of this 15-year retrospective study is to analyze the outcomes of free tissue transfers in the head and neck are...

  • Article
  • Open Access
23 Citations
7,804 Views
14 Pages

Clinico-Pathological Features and Immunohistochemical Comparison of p16, p53, and Ki-67 Expression in Muscle-Invasive and Non-Muscle-Invasive Conventional Urothelial Bladder Carcinoma

  • Abdulkarim Hasan,
  • Yasien Mohammed,
  • Mostafa Basiony,
  • Mehenaz Hanbazazh and ,
  • Abdulhadi Samman,
  • Mohamed Fayek Abdelaleem,
  • Mohamed Nasr,
  • Hesham Abozeid,
  • Hassan Ismail Mohamed and
  • Essam Mandour
  • + 15 authors+ 10 authors

Introduction: The identification of bladder detrusor muscle invasion in urothelial cancer is essential for prognosis and management. We studied the clinical, histological, and immunohistochemical expression of p16, p53, and Ki-67 in urothelial detrus...

(This article belongs to the Special Issue Teaching Pathology Towards Clinics and Practice)
  • Article
  • Open Access
2 Citations
5,011 Views
15 Pages

Firearm Injuries during Pregnancy in the USA

  • Taylor Luster and
  • Randall T. Loder

Trauma during pregnancy is the leading cause of non-pregnancy-related maternal deaths, with some due to injuries from firearms. It was the purpose of this study to characterize the patterns and presentations of firearm-associated injuries in pregnant...

(This article belongs to the Special Issue 2023 Feature Papers in Clinics and Practice)
  • Article
  • Open Access
6 Citations
3,602 Views
11 Pages

Segmental Rectum Resection for Deep Endometriosis and Excision Similarly Improve Sexual Function and Pain

  • Fernanda de Almeida Asencio,
  • Raphael Jose Palhares Fins,
  • Carolina Kami Mitie,
  • Anastasia Ussia and ,
  • Arnauld Wattiez,
  • Helizabet Salomao Ribeiro,
  • Paulo Ayrosa Ribeiro and
  • Philippe Robert Koninckx
  • + 3 authors+ 0 author

Segmental rectum resections for indications other than endometriosis were reported to result in up to 40% sexual dysfunctions. We, therefore, evaluated sexual function after low bowel resection (n = 33) for deep endometriosis in comparison with conse...

(This article belongs to the Special Issue 2023 Feature Papers in Clinics and Practice)
  • Review
  • Open Access
33 Citations
12,580 Views
12 Pages

Potential Role of Glutathione Antioxidant Pathways in the Pathophysiology and Adjunct Treatment of Psychiatric Disorders

  • Nicole Poladian,
  • Inesa Navasardyan,
  • William Narinyan,
  • Davit Orujyan and
  • Vishwanath Venketaraman

Oxidative stress is defined as the imbalance between the production of free radicals and their removal by antioxidants, leading to accumulation and subsequent organ and tissue damage. Antioxidant status and its role in the accumulation of free radica...

(This article belongs to the Special Issue 2023 Feature Papers in Clinics and Practice)
  • Article
  • Open Access
3 Citations
3,092 Views
10 Pages

Relationships between Lip Seal Strength, Tongue Pressure, and Daytime Sleepiness in Japanese Workers: A Cross-Sectional Study

  • Akira Minoura,
  • Yoshiaki Ihara,
  • Hirotaka Kato,
  • Kouzou Murakami and ,
  • Yoshio Watanabe,
  • Kojiro Hirano,
  • Yoshinori Ito and
  • Akatsuki Kokaze
  • + 3 authors+ 0 author

This cross-sectional study aimed to examine the relationships between lip seal strength, tongue pressure, and daytime sleepiness in Japanese workers. A self-administered questionnaire which comprised the Epworth Sleepiness Scale (ESS) was completed b...

(This article belongs to the Special Issue New Trends, Materials, and Technologies and Consolidating Best Practices in Dentistry)
  • Article
  • Open Access
6 Citations
4,175 Views
10 Pages

Introduction: Uncomplicated urinary tract infection (uUTI) is one of the most prevalent bacterial infections in clinical practice. Empirical treatment is used commonly; thus, knowledge of the local antimicrobial susceptibility pattern is crucial to a...

  • Article
  • Open Access
2 Citations
3,404 Views
12 Pages

25 June 2023

(1) Background: Patients who deserve intensive care unit (ICU) admission may be denied due to a lack of resources, complicating ICU triage decisions for intensive care unit (ICU) clinicians. Among the resources that may be unavailable are trained per...

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Clin. Pract. - ISSN 2039-7283