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Thalassemia Reports, Volume 16, Issue 4

2026 December - 3 articles

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Article

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13 Pages

Allogeneic Hematopoietic Cell Transplantation for Pediatric Unstable Hemoglobinopathies: An Aggregated Cohort with Long-Term Follow-Up from a Brazilian Center

Annie Karoline Feijó Costa,
Joana Teresa Bisinella de Faria,
Gabriela Ventura de Almeida Silva,
Renata Fittipaldi da Costa Guimarães and ,
Carlos Eduardo Setanni Grecco,
Thalita Cristina de Mello Costa,
Fabíola Traina,
Belinda Pinto Simões and
Luiz Guilherme Darrigo
+ 4 authors+ 0 author

Thalass. Rep.2026, 16(4), 25;https://doi.org/10.3390/thalassrep16040025

8 October 2026

Background/Objectives: Severe unstable hemoglobinopathies may cause transfusion dependence from early childhood, and allogeneic hematopoietic cell transplantation (allo-HCT) is the only established curative option. Pediatric experience with allo-HCT...

(This article belongs to the Topic New Drugs and Combinations in the Management of Hematological Malignancies and Rare Diseases)

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Article

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15 Pages

Distribution and Clustering of Beta-Thalassemia- and Sickle Cell-Related Disorders Among Scheduled Tribes in Tamil Nadu: An Exploratory Multivariate Analysis

Kezia Angeline John Chandrasekar and
Gladius Jennifer Hirudayaraj

Thalass. Rep.2026, 16(4), 24;https://doi.org/10.3390/thalassrep16040024

8 October 2026

Background/Objectives: Beta-thalassemia and sickle cell disorders are among the most common inherited hemoglobin disorders affecting tribal populations in India, with marked ethnic and geographic heterogeneity. Although exploratory multivariate appro...

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19 Pages

Mechanisms, Risk Identification, and Prevention of Thrombosis in Sickle Cell Disease and β-Thalassemia: An Updated Narrative Review

Anas Zayad and
Mohamed A. Yassin

Thalass. Rep.2026, 16(4), 23;https://doi.org/10.3390/thalassrep16040023

1 October 2026

Background: Sickle cell disease (SCD) and β-thalassemia are chronic thromboinflammatory disorders associated with venous, arterial, and microvascular thrombotic complications. However, evidence regarding disease-specific risk stratification and...

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Thalass. Rep. - ISSN 2039-4365

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