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Infectious Disease Reports, Volume 18, Issue 3

2026 June - 25 articles

Cover Story: The trajectory of influenza hospitalization burden from pre-COVID-19 pandemic baseline through post-pandemic recovery remains poorly characterized at the national level. This study characterized phase-stratified burden and seasonal structure, quantified racial and ethnic disparities, and assessed whether post-pandemic seasons represent anomalous departures from pre-pandemic expectations. Methods: Sixteen complete seasons of FluSurv-NET surveillance data (2009–2010 through 2024–2025; 509 observation weeks) were analyzed across pre-pandemic, disruption, and recovery phases using OLS regression with effect-size estimation, bootstrapped age-adjusted rate ratios, seasonal-trend decomposition (STL), Prophet time-series forecasting, and Isolation Forest anomaly detection. View this paper
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Articles (25)

  • Case Report
  • Open Access
1,293 Views
9 Pages

Cardiovascular Complications of Anaplasmosis: A Case of Acute Pulmonary Embolism and Literature Review

  • Aleksandar Gavrancic,
  • Christian M. Jacobson,
  • Veljko Rabasovic,
  • Erik Sviggum and ,
  • Jelena Stojsavljevic,
  • Nestor G. Tarragona,
  • Peter J. Mattingly and
  • Igor Dumic
  • + 3 authors+ 0 author

Background: Anaplasmosis is an emerging tick-borne infection that typically presents as a non-specific febrile illness, with variable degrees of cytopenias and liver tests abnormalities. Severe complications remain atypical and uncommon. Case Report:...

(This article belongs to the Section Bacterial Diseases)
  • Article
  • Open Access
769 Views
20 Pages

Background/Objectives: The trajectory of influenza hospitalization burden from pre-COVID-19 pandemic baseline through post-pandemic recovery remains poorly characterized at the national level. This study characterized phase-stratified burden and seas...

  • Review
  • Open Access
1 Citations
1,383 Views
16 Pages

Five Hot Topics in Tropical Medicine: 2025

  • Amanda Hempel,
  • Gregory D. Hawley,
  • Jahmar Hewitt,
  • Maxime Billick and ,
  • Adrienne J. Showler,
  • Kevin C. Kain and
  • Andrea K. Boggild
  • + 2 authors+ 0 author

In 2025, tropical medicine was shaped by advances in diagnostic technology, expanding arboviral epidemics, rapid progress in filovirus vaccine development, evolving regulatory responses to newly licensed vaccines, and translational breakthroughs addr...

(This article belongs to the Section Neglected Tropical Diseases)
  • Editorial
  • Open Access
1 Citations
703 Views
5 Pages

Ecotourism and the Hidden Ecology of Infection: The Andes Virus Cruise Outbreak

  • Laura Scorzolini,
  • Alessandra D’Abramo,
  • Enrico Girardi and
  • Emanuele Nicastri

Over the past decade, outdoor recreational activities—including ecotourism, wildlife observation, adventure travel, and expedition cruising—have expanded at an unprecedented pace [...]

(This article belongs to the Section Viral Infections)
  • Case Report
  • Open Access
1,481 Views
11 Pages

Concurrent Central and Autonomic Nervous System Involvement in Varicella-Zoster Virus Infection in an Immunocompetent Patient: A Case-Based Mechanistic Analysis

  • Jordan Pyatt,
  • Carlos A. Umaña Mejía,
  • Justice Cruz,
  • Fernando Baires and ,
  • Helen Hoffman,
  • Joanne Cordero Guerra,
  • Miguel Sierra-Hoffman,
  • Heike Hesse and
  • Amy C. Madril
  • + 4 authors+ 0 author

Background: Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus capable of causing a broad spectrum of neurologic complications beyond classic dermatomal herpes zoster. Although meningitis and encephalitis are well recognized manifestation...

  • Review
  • Open Access
1 Citations
685 Views
16 Pages

Climate Change and Emerging Arboviral Threats in Saudi Arabia: Epidemiology, Vector Ecology, and One Health Preparedness

  • Shuaibu Abdullahi Hudu,
  • Emad A. Morad,
  • Ghusun M. Alhazimi and
  • Abdulgafar Olayiwola Jimoh

Arboviral diseases are emerging as important public health threats in Saudi Arabia, driven by rapid urbanization, climate variability, the expansion of Aedes aegypti populations, international travel, and large-scale religious mass gatherings. Dengue...

  • Article
  • Open Access
1,203 Views
15 Pages

Correlation of Age and Laboratory Parameters with Urine Flow Cytometry and Culture Results in Patients with Urinary Tract Infections

  • Alma Trnacevic,
  • Emir Trnacevic,
  • Merjema Mahmutovic,
  • Amra Serak and ,
  • Humera Porobic Jahic,
  • Jasminka Petrovic,
  • Dilista Piljic,
  • Rahima Jahic,
  • Danijel Bijedic and
  • Amela Becirovic
  • + 5 authors+ 0 author

Background: The diagnosis of urinary tract infection (UTI) remains a clinical challenge, with urine culture as the gold standard. In developing countries like Bosnia and Herzegovina, a high prevalence of antimicrobial resistance and frequent empirica...

(This article belongs to the Section Bacterial Diseases)
  • Article
  • Open Access
1 Citations
1,295 Views
13 Pages

Climate Variability Drives Dengue Transmission in Bangladesh

  • Ayesha Siddiqa,
  • Prosenjit Choudhury,
  • Nabil Jahan Mahim,
  • Suman Paul and ,
  • Syed Sayeem Uddin Ahmed and
  • Md Bashir Uddin
  • + 1 author+ 0 author

Background: Dengue fever has emerged as a major public health concern in Bangladesh, with increasing incidence and geographic spread of outbreaks in recent years. This study aimed to investigate the lagged and non-linear associations between climatic...

  • Case Report
  • Open Access
1 Citations
1,209 Views
10 Pages

Salvage Treatment of Ventilator-Associated Pneumonia Using Sulbactam–Durlobactam in a Preterm Neonate: A Case Report

  • Suzana Zivojinovic,
  • Tijana Prodanovic,
  • Nikola Prodanovic,
  • Rasa Medovic and ,
  • Milica Cekerevac,
  • Dragana Savic,
  • Bojana Markovic and
  • Slobodan Jankovic
  • + 3 authors+ 0 author

Background: Ventilator-associated pneumonia (VAP) is a leading cause of nosocomial infections in neonatal intensive care units (NICUs) and is associated with significant morbidity, mortality, and prolonged hospitalization, particularly in preterm neo...

(This article belongs to the Special Issue Nosocomial Infections and Ventilator-Associated Pneumonia (VAP) in Non-Invasive Ventilatory Support)
  • Review
  • Open Access
1 Citations
2,003 Views
24 Pages

Bacterial Granulomatous Lung Diseases: Radiological Findings and Differential Diagnosis

  • Stefano Giusto Picchi,
  • Augusto Minieri,
  • Francesco Lassandro,
  • Giuseppe Russo and
  • Giulia Lassandro

Background Granulomatous lung diseases include a spectrum of disorders, both infectious and noninfectious, unified by the presence of granulomas in the lung parenchyma. Granulomas are microscopic, organized collections of immune cells that arise as a...

(This article belongs to the Section Bacterial Diseases)
  • Communication
  • Open Access
1,183 Views
11 Pages

Dirofilaria spp. Detection in Dog Blood Samples from Southern Poland—A Retrospective Data Analysis

  • Olga Pawełczyk,
  • Paulina Iwase,
  • Bartosz Wierzba and
  • Jolanta Szłapka-Kosarzewska

Background: Dirofilaria spp. is an etiological agent of dirofilariasis, a mosquito-borne parasitic disease of increasing zoonotic concern in Europe. The aim of this study was to assess the occurrence of Dirofilaria spp. in dogs from Southern Poland u...

(This article belongs to the Topic Vector-Borne Disease Spatial Epidemiology, Disease Ecology, and Zoonoses)
  • Review
  • Open Access
1,598 Views
23 Pages

Background: In March 2026, a meningococcal cluster centred on the University of Kent, England, caused two deaths and resulted in over 20 reported cases within the first week, including confirmed and suspected invasive cases. Subsequent UKHSA updates...

  • Article
  • Open Access
1,876 Views
20 Pages

Cellular Metabolic Signatures of Long COVID-19

  • Sujata Srikanth,
  • Diana Ivankovic,
  • Lucia Gonzales,
  • Delphine Dean and
  • Luigi Boccuto

Background/Objectives: Long COVID-19 (LC-19), also known as Post-Acute COVID-19 Syndrome (PACS), is a chronic condition some people experience after an initial SARS-CoV-2 infection. The etiology of this complex, multifactorial disease remains largely...

(This article belongs to the Section Viral Infections)
  • Article
  • Open Access
2,606 Views
17 Pages

Clinical Characteristics, Risk Factors, and Predictors of Fatal Outcomes and Prolonged Hospitalization of Crimean–Congo Hemorrhagic Fever Cases in Basrah, Iraq

  • Mohammed H. Al-Maliki,
  • Celine Tabche,
  • Alaa K. Mousa,
  • Ali R. Hashim and ,
  • Zeenah Atwan,
  • Hassan A. Farid,
  • Maitham G. Yousif,
  • David Rawaf,
  • Nazik Haikaz Hasrat and
  • Haydar Witwit
  • + 13 authors+ 8 authors

Background: The impact of climate change on birds’ migration and ticks’ reservoir habits is contributing to the spread of Crimean–Congo hemorrhagic fever (CCHF), caused by CCHF virus (CCHFV), to new continents and countries. CCHF is...

  • Article
  • Open Access
563 Views
13 Pages

Necrotizing Fasciitis in Northern Italy: Clinical Characteristics, Risk Factors, and Prognostic Value of the LRINEC Score—A Single-Center Retrospective Case Series

  • Aurelia Sangani,
  • Flavia Puci,
  • Davide Tirro,
  • Simona Villani and ,
  • Camilla Torriani,
  • Enrico Brunetti,
  • Raffaele Bruno and
  • Elisabetta Pagani
  • + 3 authors+ 0 author

Background: Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft tissue infection characterized by fascial necrosis, with mortality rates of 20–30%. Despite its rarity, NF is increasingly encountered due to the rising prev...

  • Article
  • Open Access
2,844 Views
12 Pages

Association of Climatic Factors with Frequency of Dengue

  • Gracia Viviana González-Enríquez,
  • Blanca Miriam Torres-Mendoza,
  • Martha Escoto-Delgadillo,
  • Efrain Chavarria-Avila and ,
  • Sagrario Karina Esparza-Avila,
  • Clara Esperanza Santacruz-Tinoco,
  • Bernardo Martínez-Miguel,
  • Magally Farah Diva Arenas-Sevilla and
  • David Israel Javalera Castro
  • + 4 authors+ 0 author

Background: Climate change has contributed to the global resurgence of dengue, with a spike of more than 14.4 million dengue cases. This study aimed to analyze the association between dengue frequency with climatic factors, circulating serotypes, and...

(This article belongs to the Section Viral Infections)
  • Article
  • Open Access
1,766 Views
13 Pages

Background: Superficial fungal infections caused by dermatophyte and non-dermatophyte species are increasing globally. While several comorbid diseases and risk factors have been associated with fungal infections at the individual level, their epidemi...

(This article belongs to the Section Fungal Infections)
  • Article
  • Open Access
507 Views
9 Pages

Facility-Level Access Drives Disparities in Influenza and Pneumococcal Vaccination in Long-Term Care Facilities in Southern Poland

  • Zofia Gniadek,
  • Estera Jachowicz-Matczak,
  • Cezary Kapturkiewicz,
  • Izabella Bylica and ,
  • Dorota Romaniszyn and
  • Jadwiga Wójkowska-Mach
  • + 1 author+ 0 author

Background: Vaccinations prevent severe respiratory infections in older adults, yet uptake in Polish long-term care facilities (LTCFs) remains poorly characterized. We assessed influenza and pneumococcal vaccination coverage and factors associated wi...

  • Review
  • Open Access
1,223 Views
18 Pages

Background/Objectives: The increasing burden of multidrug-resistant (MDR) microorganisms and limited resources in healthcare settings are making traditional strategies based on routine isolation of all carriers unsustainable. Methods: A clinical narr...

(This article belongs to the Special Issue Prevention, Diagnosis and Treatment of Healthcare-Associated Infections)
  • Article
  • Open Access
766 Views
15 Pages

A Real-World Pharmacovigilance Analysis of the Safety Profiles Associated with Anti-MRSA Agents Using the Japanese Adverse Drug Event Report (JADER) Database

  • Yuki Hanai,
  • Shusuke Uekusa,
  • Mizuki Mori,
  • Kohei Shimoyama and ,
  • Hayato Ohashi,
  • Koji Nishimura,
  • Sachiko Yanagino,
  • Takahiro Matsumoto and
  • Kazuhiro Matsuo
  • + 4 authors+ 0 author

Background: Anti-MRSA agents are essential for treating severe infections, yet their use is constrained by distinct toxicity profiles. However, comparative real-world data remain scarce. Methods: This nationwide pharmacovigilance study used the Japan...

(This article belongs to the Section Bacterial Diseases)
  • Article
  • Open Access
1,207 Views
22 Pages

Chromosomal Mechanisms of Colistin Resistance in Clinical Isolates of Carbapenem-Resistant Klebsiella pneumoniae from a Tunisian Tertiary-Care Hospital

  • Zaineb Hamzaoui,
  • Hajer Kilani,
  • Alain Ocampo-Sosa,
  • Sana Ferjani and ,
  • Elaa Maamar,
  • Lamia Kanzari,
  • Ahmed Fakhfakh,
  • Amel Rehaiem,
  • Luis Martínez-Martínez and
  • Ilhem Boutiba Ben Boubaker
  • + 5 authors+ 0 author

Background/Objectives: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major nosocomial pathogen. Although newer agents have reduced colistin use in high-income countries, this polymyxin remains important in many low- and middle-income setting...

(This article belongs to the Section Antimicrobial Stewardship and Resistance)
  • Review
  • Open Access
1,044 Views
13 Pages

Non-Albicans Candida Peritonitis in Peritoneal Dialysis: Species Distribution, Management, and Outcomes—A Systematic Case-Based Review

  • John Dotis,
  • Athina Papadopoulou,
  • Maria Fourikou,
  • Marianna Papakonstantinou and ,
  • Ioustini Kalaitzopoulou and
  • Charalampos Antachopoulos
  • + 1 author+ 0 author

Background/Objectives: Fungal peritonitis is a severe complication of peritoneal dialysis (PD) associated with catheter removal, technique failure, and increased mortality. Although Candida albicans was traditionally the predominant pathogen, non-alb...

(This article belongs to the Section Fungal Infections)
  • Review
  • Open Access
1 Citations
2,218 Views
15 Pages

Cardiovascular Manifestations Documented in Patients with Lyme Disease: Clinical Presentation, Management Strategies, and Outcomes

  • Luis Antonio Cortes Islas,
  • Priscila Mishelle Bartolo Gomez,
  • Nora Denice Cuevas Obispo,
  • Ayelen Xicohtencatl Muñoz and ,
  • Lao Yuling Lopez Lucero and
  • Juan Pablo Ramirez Hinojosa
  • + 1 author+ 0 author

Background/Objectives: Lyme disease is a tick-borne zoonosis caused by Borrelia burgdorferi that can affect multiple organ systems. Although cardiovascular involvement is considered uncommon, it may lead to severe and potentially life-threatening com...

(This article belongs to the Section Bacterial Diseases)
  • Case Report
  • Open Access
1,897 Views
11 Pages

Spontaneous Pneumomediastinum, Subcutaneous Emphysema, and Pneumoperitoneum in RT-PCR-Confirmed Measles: A Pediatric Case Report

  • Roberto Miguel Damián-Negrete,
  • Alondra Denisse Hernández-Luna,
  • Rocío Guadalupe Cano-Arias,
  • Antonio Durán-Plaza and ,
  • Judith Carolina De Arcos-Jiménez,
  • Kathya Analí Rodríguez-González,
  • Braulio Dazahel González-Flores,
  • Pedro Iván Navarro-González and
  • Jaime Briseno-Ramírez
  • + 4 authors+ 0 author

Measles remains a major global public health challenge as declining vaccination coverage fuels outbreaks worldwide. Although pneumonia is the most recognized respiratory complication, spontaneous air leak syndrome—including pneumomediastinum, s...

(This article belongs to the Special Issue Viral Infectious Diseases: Epidemiology and Prevention Through Vaccination)
  • Review
  • Open Access
1,526 Views
19 Pages

HBV and the Microbiome—PubMed Database Literature Review

  • Anna Marija Prince,
  • Indra Zeltiņa,
  • Aigars Reinis,
  • Olga Valciņa and
  • Angelika Krūmiņa

Objective: Hepatitis B virus (HBV) is a globally distributed infectious disease affecting the liver. This literature review aims to summarize all available relevant information on the PubMed database about HBV’s connection to the microbiome and...

(This article belongs to the Section Viral Infections)
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Infect. Dis. Rep. - ISSN 2036-7449