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Viruses, Volume 15, Issue 7

July 2023 - 213 articles

Cover Story: How do viruses find their hosts? In a laboratory, viruses and host cells are mixed, but in nature, it is wilderness. Viruses may encode sensors such as Hoc, as was found in bacteriophage T4 and other phages. The capsid is decorated with Hoc fibers that help navigate the virus’ movements to reach the host. Phages cluster or disperse, piggyback on bacteria to go to distant places, or persist in gut mucosa rich in host bacteria, and so on. Thus, even the tiniest life forms may be equipped with devices to sense, navigate, and survive. The flexibility of the Hoc fiber structure and its interaction with capsid lattice and electrostatic surface are well-evolved to serve as sensors. Such genes are often overlooked using a narrow definition of a laboratory virus infection but are essential in the natural environment. View this paper
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Articles (213)

  • Article
  • Open Access
9 Citations
2,424 Views
12 Pages

Evidence for Microchimerism in Baboon Recipients of Pig Hearts

  • Hina Jhelum,
  • Martin Bender,
  • Bruno Reichart,
  • Maren Mokelke,
  • Julia Radan,
  • Elisabeth Neumann,
  • Ludwig Krabben,
  • Jan-Michael Abicht,
  • Benedikt Kaufer and
  • Matthias Längin
  • + 1 author

24 July 2023

Xenotransplantation, like allotransplantation, is usually associated with microchimerism, i.e., the presence of cells from the donor in the recipient. Microchimerism was reported in first xenotransplantation trials in humans, as well as in most precl...

  • Article
  • Open Access
7 Citations
3,117 Views
13 Pages

Genetic Variability and Molecular Evolution of Tomato Mosaic Virus Populations in Three Northern China Provinces

  • Jinfu Lyu,
  • Yuanyuan Yang,
  • Xiaohui Sun,
  • Shanshan Jiang,
  • Hao Hong,
  • Xiaoping Zhu and
  • Yongguang Liu

24 July 2023

RNA viruses tend to mutate during transmission and host infection, which is critical to viral adaptation and evolution. Tomato mosaic virus (ToMV) is a member of the genus Tobamovirus (family Virgaviridae) and an economically important virus with det...

  • Article
  • Open Access
7 Citations
2,230 Views
21 Pages

Differences in Trends in Admissions and Outcomes among Patients from a Secondary Hospital in Madrid during the COVID-19 Pandemic: A Hospital-Based Epidemiological Analysis (2020–2022)

  • Rafael Garcia-Carretero,
  • Oscar Vazquez-Gomez,
  • María Ordoñez-Garcia,
  • Noelia Garrido-Peño,
  • Ruth Gil-Prieto and
  • Angel Gil-de-Miguel

24 July 2023

Spain had some of Europe’s highest incidence and mortality rates for coronavirus disease 2019 (COVID-19). This study highlights the impact of the COVID-19 pandemic on daily health care in terms of incidence, critical patients, and mortality. We...

  • Systematic Review
  • Open Access
3 Citations
4,325 Views
19 Pages

Maternal Fever and Reduced Fetal Movement as Predictive Risk Factors for Adverse Neonatal Outcome in Cases of Congenital SARS-CoV-2 Infection: A Meta-Analysis of Individual Participant Data from Case Reports and Case Series

  • Elena S. Bernad,
  • Florentina Duica,
  • Panagiotis Antoniadis,
  • Andreea Moza,
  • Diana Lungeanu,
  • Marius Craina,
  • Brenda C. Bernad,
  • Edida Maghet,
  • Ingrid-Andrada Vasilache and
  • Anca Laura Maghiari
  • + 2 authors

24 July 2023

Objectives: To determine risk factors for primary and secondary adverse neonatal outcomes in newborns with congenital SARS-CoV-2 infection. Data sources: PubMed/MEDLINE and Google Scholar from January 2020 to January 2022. Study eligibility criteria:...

  • Article
  • Open Access
8 Citations
2,371 Views
12 Pages

23 July 2023

Type II grass carp reovirus (GCRV-II) with high pathogenicity and infectivity causes severe hemorrhagic disease, which leads to extensive death in the grass carp and black carp aquaculture. However, the early invasion portal remains unclear. In this...

  • Article
  • Open Access
5 Citations
2,334 Views
12 Pages

Fatty Acids Composition and HIV Infection: Altered Levels of n-6 Polyunsaturated Fatty Acids Are Associated with Disease Progression

  • Thor Ueland,
  • Bjørn Waagsbø,
  • Rolf K. Berge,
  • Marius Trøseid,
  • Pål Aukrust and
  • Jan K. Damås

23 July 2023

Fatty acids (FAs) are important regulators of immune responses and innate defense mechanisms. We hypothesized that disturbed FA metabolism could contribute to the progression of HIV infection. Plasma levels of 45 FAs were analyzed with gas chromatogr...

  • Article
  • Open Access
13 Citations
2,463 Views
12 Pages

Lipids and Transaminase in Antiretroviral-Treatment-Experienced People Living with HIV, Switching to a Doravirine-Based vs. a Rilpivirine-Based Regimen: Data from a Real-Life Setting

  • Paolo Maggi,
  • Elena Delfina Ricci,
  • Canio Vito Martinelli,
  • Giuseppe Vittorio De Socio,
  • Nicola Squillace,
  • Chiara Molteni,
  • Addolorata Masiello,
  • Giancarlo Orofino,
  • Barbara Menzaghi and
  • Rita Bellagamba
  • + 19 authors

23 July 2023

Doravirine (DOR) is a newly approved non-nucleoside reverse transcriptase inhibitor (NNRTI). We aimed to investigate, in a real-life setting, how switching to a DOR-based regimen rather than a rilpivirine (RPV)-based regimen impacted metabolic and he...

  • Article
  • Open Access
3 Citations
2,336 Views
18 Pages

Widespread Reassortment Contributes to Antigenic Shift in Bluetongue Viruses from South Africa

  • Antoinette Van Schalkwyk,
  • Peter Coetzee,
  • Karen Ebersohn,
  • Beate Von Teichman and
  • Estelle Venter

23 July 2023

Bluetongue (BT), a viral disease of ruminants, is endemic throughout South Africa, where outbreaks of different serotypes occur. The predominant serotypes can differ annually due to herd immunity provided by annual vaccinations using a live attenuate...

  • Article
  • Open Access
10 Citations
2,600 Views
14 Pages

Nonenveloped Avian Reoviruses Released with Small Extracellular Vesicles Are Highly Infectious

  • Zuopei Wang,
  • Menghan He,
  • Han He,
  • Kyle Kilby,
  • Roberto de Antueno,
  • Elizabeth Castle,
  • Nichole McMullen,
  • Zhuoyu Qian,
  • Tzviya Zeev-Ben-Mordehai and
  • Roy Duncan
  • + 1 author

23 July 2023

Vesicle-encapsulated nonenveloped viruses are a recently recognized alternate form of nonenveloped viruses that can avoid immune detection and potentially increase systemic transmission. Avian orthoreoviruses (ARVs) are the leading cause of various d...

  • Article
  • Open Access
1 Citations
1,943 Views
13 Pages

Clinical Profile of SARS-CoV-2 Infection: Mechanisms of the Cellular Immune Response and Immunogenetic Markers in Patients from Brazil

  • Vanessa Pacheco,
  • Rosane Cuber Guimarães,
  • Danielly Corrêa-Moreira,
  • Carlos Eduardo Magalhães,
  • Douglas Figueiredo,
  • Patricia Guttmann,
  • Gisela Freitas Trindade,
  • Juliana Fernandes Amorim da Silva,
  • Ana Paula Dinis Ano Bom and
  • Maria de Lourdes Maia
  • + 5 authors

23 July 2023

Objectives: The aim of this study is to evaluate some mechanisms of the immune response of people infected with SARS-CoV-2 in both acute infection and early and late convalescence phases. Methods: This is a cohort study of 70 cases of COVID-19, confi...

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Viruses - ISSN 1999-4915