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Viruses, Volume 15, Issue 6

June 2023 - 188 articles

Cover Story: Tools to rapidly quantify secreted viral particles are scarce, impeding progress in antiviral screens of viral assembly. By serendipity, Gullberg and Frydman discovered a unique feature of coronaviruses, namely that they will package a small reporter protein expressed in infected host cells. Using luciferase constructs of varying sizes and sub-cellular localization, they demonstrate that small cytoplasmic proteins are non-specifically packaged into budding coronavirus virions. Furthermore, they demonstrate that the small reporter nanoLuciferase is packaged directly inside SARS-CoV2 virions and VLPs, as well as other common cold coronaviruses, but not in the smaller flavivirus virions. Their findings provide a rapid strategy to measure secreted virions that can be deployed to gain fundamental insights into coronavirus assembly and egress and open new avenues for antiviral discovery. View this paper
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Articles (188)

  • Article
  • Open Access
8 Citations
3,368 Views
11 Pages

Immunogenicity of Oral Rabies Vaccine Strain SPBN GASGAS in Local Dogs in Bali, Indonesia

  • Irene Linda Megawati Saputra,
  • Suwarno Suwarno,
  • Wahid Fakhri Husein,
  • Pebi Purwo Suseno,
  • I Made Angga Prayoga,
  • Ad Vos,
  • I Made Arthawan,
  • Luuk Schoonman,
  • John Weaver and
  • Nuryani Zainuddin

20 June 2023

Dog-mediated rabies is endemic in much of Indonesia, including Bali. Most dogs in Bali are free-roaming and often inaccessible for parenteral vaccination without special effort. Oral rabies vaccination (ORV) is considered a promising alternative to i...

  • Communication
  • Open Access
11 Citations
3,833 Views
12 Pages

Genetic Characterization and Pathogenesis of H5N1 High Pathogenicity Avian Influenza Virus Isolated in South Korea during 2021–2022

  • Ra Mi Cha,
  • Yu-Na Lee,
  • Min-Ji Park,
  • Yoon-Gi Baek,
  • Jae-In Shin,
  • Chang Hwa Jung,
  • Mingeun Sagong,
  • Gyeong-Beom Heo,
  • Yong-Myung Kang and
  • Kwang-Nyeong Lee
  • + 2 authors

20 June 2023

High pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4 H5Nx have been circulating in poultry and wild birds worldwide since 2014. In South Korea, after the first clade 2.3.4.4b H5N1 HPAI viruses were isolated from wild birds in October 20...

  • Article
  • Open Access
2,183 Views
11 Pages

Influence of SARS-CoV-2 Status and Aging on the Nasal and Fecal Immunological Profiles of Elderly Individuals Living in Nursing Homes

  • Claudio Alba,
  • Marta Mozota,
  • Rebeca Arroyo,
  • Natalia Gómez-Torres,
  • Irma Castro and
  • Juan Miguel Rodríguez

20 June 2023

In the frame of SARS-CoV-2 infection, studies regarding cytokine profiling of mucosal-related samples are scarce despite being the primary infection sites. The objective of this study was to compare the nasal and fecal inflammatory profiles of elderl...

  • Article
  • Open Access
3 Citations
2,384 Views
14 Pages

20 June 2023

Astroviruses are small nonenveloped single-stranded RNA viruses with a positive sense genome. They are known to cause gastrointestinal disease in a broad spectrum of species. Although astroviruses are distributed worldwide, a gap in knowledge of thei...

  • Article
  • Open Access
5 Citations
2,967 Views
13 Pages

Proteomics Identified UDP-Glycosyltransferase Family Members as Pro-Viral Factors for Turnip Mosaic Virus Infection in Nicotiana benthamiana

  • Kaida Ding,
  • Zhaoxing Jia,
  • Penghuan Rui,
  • Xinxin Fang,
  • Hongying Zheng,
  • Jianping Chen,
  • Fei Yan and
  • Guanwei Wu

20 June 2023

Viruses encounter numerous host factors that facilitate or suppress viral infection. Although some host factors manipulated by viruses were uncovered, we have limited knowledge of the pathways hijacked to promote viral replication and activate host d...

  • Article
  • Open Access
1,993 Views
10 Pages

Validity of Rapid Antibody Testing for COVID-19 Vaccine in Homeless People

  • Se-Min Hwang,
  • Yun Jung,
  • Jiyeon Seo,
  • Yoomi Jung,
  • Shinae Park and
  • Haesook Seo

20 June 2023

(1) Background: There is a paucity of data regarding the validity of rapid antibody testing for SARS-CoV-2 vaccine response in homeless people worldwide. The objective of this study was to evaluate a rapid SARS-CoV-2 IgM/IgG antibody detection kit as...

  • Article
  • Open Access
5 Citations
3,773 Views
17 Pages

Unbiased Virus Detection in a Danish Zoo Using a Portable Metagenomic Sequencing System

  • Anna S. Fomsgaard,
  • Stamatios A. Tahas,
  • Katja Spiess,
  • Charlotta Polacek,
  • Jannik Fonager and
  • Graham J. Belsham

20 June 2023

Metagenomic next-generation sequencing (mNGS) is receiving increased attention for the detection of new viruses and infections occurring at the human–animal interface. The ability to actively transport and relocate this technology enables in si...

  • Article
  • Open Access
7 Citations
2,770 Views
14 Pages

20 June 2023

The Omicron variants of SARS-CoV-2 have emerged as the dominant strains worldwide, causing the COVID-19 pandemic. Each Omicron subvariant contains at least 30 mutations on the spike protein (S protein) compared to the original wild-type (WT) strain....

  • Article
  • Open Access
8 Citations
3,084 Views
18 Pages

Diversity of Human Enterovirus Co-Circulations in Five Kindergartens in Bangkok between July 2019 and January 2020

  • Pichamon Sittikul,
  • Elizabeth M. Batty,
  • Prasert Yodsawat,
  • Jiratchaya Nuanpirom,
  • Nathamon Kosoltanapiwat,
  • Unitsa Sangket,
  • Supawat Chatchen,
  • Nicholas P. J. Day and
  • Janjira Thaipadungpanit

20 June 2023

Human enterovirus causes various clinical manifestations in the form of rashes, febrile illness, flu-like illness, uveitis, hand–foot–mouth disease (HFMD), herpangina, meningitis, and encephalitis. Enterovirus A71 and coxsackievirus are s...

  • Article
  • Open Access
5 Citations
2,705 Views
14 Pages

19 June 2023

The cucurbit vegetable chieh-qua (Benincasa hispida var. chieh-qua How) is an important crop in South China and southeast Asian countries. Viral diseases cause substantial loss of chieh-qua yield. To identify the viruses that affect chieh-qua in Chin...

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Viruses - ISSN 1999-4915