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Viruses, Volume 12, Issue 7

July 2020 - 94 articles

Cover Story: The large capsids, or heads, of giant phages are unusual, containing not only their long genomes, but in many instances a large amount of protein that is ejected into the host bacterial cell. How giant phage heads form is mostly undefined. In this study, the proteolysis of head proteins by the prohead protease was shown to be essential for head maturation of giant Salmonella virus SPN3US. In the absence of proteolysis, precursor head structures remained anchored to the Salmonella inner membrane, thus preventing packaging of the genomic DNA and addition of the tail. View this paper
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Articles (94)

  • Article
  • Open Access
8 Citations
8,792 Views
15 Pages

Establishment of a Simple and Efficient Reverse Genetics System for Canine Adenoviruses Using Bacterial Artificial Chromosomes

  • Hiromichi Matsugo,
  • Tomoya Kobayashi-Kitamura,
  • Haruhiko Kamiki,
  • Hiroho Ishida,
  • Akiko Takenaka-Uema,
  • Shin Murakami and
  • Taisuke Horimoto

16 July 2020

Canine adenoviruses (CAdVs) are divided into pathotypes CAdV1 and CAdV2, which cause infectious hepatitis and laryngotracheitis in canid animals, respectively. They can be the backbones of viral vectors that could be applied in recombinant vaccines o...

  • Article
  • Open Access
21 Citations
5,090 Views
15 Pages

Minimum Infective Dose of a Lumpy Skin Disease Virus Field Strain from North Macedonia

  • Janika Wolff,
  • Kiril Krstevski,
  • Martin Beer and
  • Bernd Hoffmann

16 July 2020

Infection with Lumpy Skin Disease virus (LSDV), as well as infections with other Capripox virus species, are described as the most severe pox diseases of production animals and are therefore listed as notifiable diseases under the guidelines of the W...

  • Article
  • Open Access
174 Citations
10,823 Views
29 Pages

Deploying Machine and Deep Learning Models for Efficient Data-Augmented Detection of COVID-19 Infections

  • Ahmed Sedik,
  • Abdullah M Iliyasu,
  • Basma Abd El-Rahiem,
  • Mohammed E. Abdel Samea,
  • Asmaa Abdel-Raheem,
  • Mohamed Hammad,
  • Jialiang Peng,
  • Fathi E. Abd El-Samie and
  • Ahmed A. Abd El-Latif

16 July 2020

This generation faces existential threats because of the global assault of the novel Corona virus 2019 (i.e., COVID-19). With more than thirteen million infected and nearly 600000 fatalities in 188 countries/regions, COVID-19 is the worst calamity si...

  • Article
  • Open Access
13 Citations
3,937 Views
14 Pages

An Assessment of Secondary Clinical Disease, Milk Production and Quality, and the Impact on Reproduction in Holstein Heifers and Cows from a Single Large Commercial Herd Persistently Infected with Bovine Viral Diarrhea Virus Type 2

  • Natália Sobreira Basqueira,
  • Jean Silva Ramos,
  • Fabricio Dias Torres,
  • Liria Hiromi Okuda,
  • David John Hurley,
  • Christopher C. L. Chase,
  • Anny Raissa Carolini Gomes and
  • Viviani Gomes

15 July 2020

The aim of this study was to evaluate secondary clinical disease, milk production efficiency and reproductive performance of heifers and cows persistently infected (PI) with bovine viral diarrhea virus type 2 (BVDV type 2). PI animals (n = 25) were i...

  • Article
  • Open Access
20 Citations
4,917 Views
17 Pages

15 July 2020

The lytic and lysogenic life cycles of marine phages are influenced by environmental conditions such as solar radiation, temperature, and host abundance. Temperature can regulate phage infection, but its role is difficult to discern in oligotrophic w...

  • Article
  • Open Access
20 Citations
4,851 Views
14 Pages

Cocirculation of Swine H1N1 Influenza A Virus Lineages in Germany

  • Roland Zell,
  • Marco Groth,
  • Andi Krumbholz,
  • Jeannette Lange,
  • Anja Philipps and
  • Ralf Dürrwald

15 July 2020

The genome analysis of 328 H1N1 swine influenza virus isolates collected in a 13-year long-term swine influenza surveillance in Germany is reported. Viral genomes were sequenced with the Illumina next-generation sequencing technique and conventional...

  • Article
  • Open Access
21 Citations
6,255 Views
13 Pages

Attach Me If You Can: Murine Norovirus Binds to Commensal Bacteria and Fungi

  • Jasmine L. Madrigal,
  • Sutonuka Bhar,
  • Samantha Hackett,
  • Haley Engelken,
  • Ross Joseph,
  • Nemat O. Keyhani and
  • Melissa K. Jones

14 July 2020

The presence of commensal bacteria enhances both acute and persistent infection of murine noroviruses. For several enteric viral pathogens, mechanisms by which these bacteria enhance infection involve direct interactions between the virus and bacteri...

  • Article
  • Open Access
5 Citations
6,327 Views
38 Pages

Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses

  • Keylie M. Gibson,
  • Margaret C. Steiner,
  • Uzma Rentia,
  • Matthew L. Bendall,
  • Marcos Pérez-Losada and
  • Keith A. Crandall

14 July 2020

Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many bioinformatic tools on consensus sequence construction has precluded a thorough analysis of intra-host...

  • Article
  • Open Access
20 Citations
4,948 Views
14 Pages

Kikwit Ebola Virus Disease Progression in the Rhesus Monkey Animal Model

  • Richard S. Bennett,
  • James Logue,
  • David X. Liu,
  • Rebecca J. Reeder,
  • Krisztina B. Janosko,
  • Donna L. Perry,
  • Timothy K. Cooper,
  • Russell Byrum,
  • Danny Ragland and
  • Marisa St. Claire
  • + 11 authors

14 July 2020

Ongoing Ebola virus disease outbreaks in the Democratic Republic of the Congo follow the largest recorded outbreak in Western Africa (2013–2016). To combat outbreaks, testing of medical countermeasures (therapeutics or vaccines) requires a well...

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Viruses - ISSN 1999-4915