Current Oncology, Volume 19, Issue 4

There is a growing need to discern how health care systems in general and the oncology “world” in particular will care for cancer survivors. In all industrialized countries, the number of cancer survivors is growing exponentially. [...]

The stages of breast cancer range from 0 to IV. In proper usage, “stage” describes the cancer at diagno-sis, although “stage” is also loosely used to describe cancer progression. For example, a stage II cancer is sometimes said to have prog...

Introduction: Large randomized trials assessing the benefit of adjuvant trastuzumab in early-stage breast cancer positive for the human epidermal growth factor receptor 2 (her2) have demonstrated a significant improvement in survival. The objective o...

Inhibitors of the vascular endothelial growth factor (vegf-is) signalling pathway have fundamentally changed the treatment of metastatic renal cell carcinoma (mrcc). Hypertension is one of the most common side effects of vegf-is and has been reported...

Objectives: We set out to create a psychosocial oncology care framework and a set of relevant recommendations that can be used to (1) improve the quality of comprehensive cancer care for Ontario patients and their families. (2) meet the psy...

Numerous reports have demonstrated that liver transplantation for neuroendocrine tumour metastasis is feasible. However, perioperative risks and long-term recurrences remain significant concerns. When liver transplantation is combined with extensive...

Five-year relative survival statistics are often used to measure cancer control across jurisdictions, and international comparisons such as the CONCORD or EUROCARE studies often point to substantial survival differences across participating countries...

Tobacco, derived from flu-cured leaves of Nicotiana tabacum, a herb native to South America, was introduced by Sir Walter Raleigh to Europe from the Americas in the 17th century. From about 1680, tobacco use became a global, common, and legal habit,...

Purpose: Multidisciplinary cancer conferences (mccs) are designed to optimize patient outcomes. It appears intuitive that mccs are essential to clinical decision-making and patient management; however, it is unclear whether that belief is supported b...

Background: Use of granulocyte colony-stimulating factor (g-csf) as primary prophylaxis against chemotherapy-induced neutropenia has significant cost implications. We examined use of g-csf for early-stage breast cancer patients at our centre. The stu...

Questions: What is the optimal strategy for preoperative identification of the adnexal mass suspicious for ovarian cancer? What is the most appropriate surgical procedure for a woman who presents with an adnexal mass suspicious for malignancy? Persp...

Objective: The objective of the present study was to evaluate the incidence, time of onset, and extent of hemoglobin, testosterone, and erythropoietin changes in patients with localized prostate cancer receiving either radiation alone or radiation co...

Purpose: Outcomes after treatment with accelerated hypofractionated radiotherapy in stage i medically inoperable non-small-cell lung cancer (nsclc) patients were determined. Methods: Our single-institution retrospective review looked at medically ino...

Background: Approximately 10% of new breast cancer patients will present with overt synchronous metastatic disease. The optimal local management of those patients is controversial. Several series suggest that removal of the primary tumour is associat...

Objective: Bicalutamide is approved as an adjuvant to primary treatments (radical prostatectomy or radiotherapy) or as monotherapy in men with locally advanced, nonmetastatic prostate cancer (pca). However, this treatment induces gynecomastia in most...

Histiocytic sarcoma is diagnosed according to established criteria. However, treatment is controversial: although lymphoma chemotherapy regimens are often used, their impact on the natural history of the disease is unclear. Here, we report a disease-...

Uterine leiomyosarcomas are rare tumours, and secondary cardiac metastases are even rarer. We present the case of a 56-year-old ethnic Chinese woman who was being treated with adjuvant pelvic radiation for uterine leiomyosarcoma when she presented wi...

Enlarging or new lesions frequently appear on magnetic resonance imaging (mri) after concurrent administration of radiation therapy and temozolomide in glioblastoma multiforme (gbm) patients. However, in nearly half such cases, the observed radiologi...

Paraneoplastic acanthosis nigricans (pan ) is an infrequently encountered cutaneous manifestation of internal malignancy. Here, we describe a case of pan in the setting of a known breast ductal carcinoma in situ, which, to our knowledge, had not been...