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Current Oncology
Volume 19
Issue 4
10.3747/co.19.997
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Case Report

Occult Cause of Paraneoplastic Acanthosis Nigricans in a Patient with Known Breast Dcis: Case and Review

by
B.D. Jakubovic
,
H.F. Sawires
2 and
D.N. Adam
3,*
1
Faculty of Medicine, University of Toronto, Toronto, ON, Canada
2
Division of General Surgery and Surgical Oncology, Toronto East General Hospital, University of Toronto, Toronto, ON, Canada
3
Department of Medicine, Division of Dermatology, St. Michael’s Hospital, University of Toronto, Toronto, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2012, 19(4), 299-302; https://doi.org/10.3747/co.19.997
Submission received: 2 May 2012 / Revised: 4 June 2012 / Accepted: 6 July 2012 / Published: 1 August 2012

Abstract

Paraneoplastic acanthosis nigricans (pan ) is an infrequently encountered cutaneous manifestation of internal malignancy. Here, we describe a case of pan in the setting of a known breast ductal carcinoma in situ, which, to our knowledge, had not been described in association with pan. As a result, thorough investigation was undertaken to search for another concurrent neoplasm that would better explain the development of pan. In so doing, we identified a coexisting metastatic cholangiocarcinoma. We thus conclude that when pan is observed in an uncommon association with a known malignancy, further investigation should be undertaken to explore whether a more likely occult culprit exists.
Keywords: acanthosis nigricans; paraneoplastic acanthosis nigricans; cholangiocarcinoma; ductal carcinoma in situ acanthosis nigricans; paraneoplastic acanthosis nigricans; cholangiocarcinoma; ductal carcinoma in situ

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MDPI and ACS Style

Jakubovic, B.D.; Sawires, H.F.; Adam, D.N. Occult Cause of Paraneoplastic Acanthosis Nigricans in a Patient with Known Breast Dcis: Case and Review. Curr. Oncol. 2012, 19, 299-302. https://doi.org/10.3747/co.19.997

AMA Style

Jakubovic BD, Sawires HF, Adam DN. Occult Cause of Paraneoplastic Acanthosis Nigricans in a Patient with Known Breast Dcis: Case and Review. Current Oncology. 2012; 19(4):299-302. https://doi.org/10.3747/co.19.997

Chicago/Turabian Style

Jakubovic, B.D., H.F. Sawires, and D.N. Adam. 2012. "Occult Cause of Paraneoplastic Acanthosis Nigricans in a Patient with Known Breast Dcis: Case and Review" Current Oncology 19, no. 4: 299-302. https://doi.org/10.3747/co.19.997

APA Style

Jakubovic, B. D., Sawires, H. F., & Adam, D. N. (2012). Occult Cause of Paraneoplastic Acanthosis Nigricans in a Patient with Known Breast Dcis: Case and Review. Current Oncology, 19(4), 299-302. https://doi.org/10.3747/co.19.997

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