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Marine Drugs, Volume 13, Issue 10

2015 October - 29 articles

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Articles (29)

  • Article
  • Open Access
43 Citations
8,012 Views
16 Pages

23 October 2015

Fucoxanthin and its deacetylated metabolite fucoxanthinol are two major carotenoids that have been confirmed to possess various pharmacological properties. In the present study, fucoxanthinol was identified as the deacetylated metabolite of fucoxanth...

  • Article
  • Open Access
44 Citations
11,820 Views
13 Pages

Production of Hyaluronic Acid by Streptococcus zooepidemicus on Protein Substrates Obtained from Scyliorhinus canicula Discards

  • José A. Vázquez,
  • Lorenzo Pastrana,
  • Carmen Piñeiro,
  • José A. Teixeira,
  • Ricardo I. Pérez-Martín and
  • Isabel R. Amado

23 October 2015

This work investigates the production of hyaluronic acid (H) by Streptococcus equi subsp. zooepidemicus in complex media formulated with peptones obtained from Scyliorhinus canicula viscera by-products. Initially, in batch cultures, the greatest prod...

  • Article
  • Open Access
49 Citations
8,615 Views
16 Pages

Alkaloids with Cardiovascular Effects from the Marine-Derived Fungus Penicillium expansum Y32

  • Ya-Qin Fan,
  • Pei-Hai Li,
  • Ya-Xi Chao,
  • Hao Chen,
  • Ning Du,
  • Qiu-Xia He and
  • Ke-Chun Liu

22 October 2015

Three new alkaloids (1, 4 and 8), together with nine known analogues (2, 3, 5–7, and 9–12), were isolated from the marine-derived fungus Penicillium expansum Y32. Their structures including the absolute configurations were elucidated by spectroscopi...

  • Review
  • Open Access
18 Citations
8,042 Views
16 Pages

22 October 2015

Okadaic acid (OA) and microcystin (MC) as well as several other microbial toxins like nodularin and calyculinA are known as tumor promoters as well as inducers of apoptotic cell death. Their intracellular targets are the major serine/threonine protei...

  • Article
  • Open Access
5 Citations
8,391 Views
17 Pages

Matrix Production, Pigment Synthesis, and Sporulation in a Marine Isolated Strain of Bacillus pumilus

  • Blanda Di Luccia,
  • Antonio Riccio,
  • Adele Vanacore,
  • Loredana Baccigalupi,
  • Antonio Molinaro and
  • Ezio Ricca

21 October 2015

The ability to produce an extracellular matrix and form multicellular communities is an adaptive behavior shared by many bacteria. In Bacillus subtilis, the model system for spore-forming bacteria, matrix production is one of the possible differentia...

  • Article
  • Open Access
19 Citations
7,424 Views
18 Pages

A Cultivated Form of a Red Seaweed (Chondrus crispus), Suppresses β-Amyloid-Induced Paralysis in Caenorhabditis elegans

  • Jatinder Singh Sangha,
  • Owen Wally,
  • Arjun H. Banskota,
  • Roumiana Stefanova,
  • Jeff T. Hafting,
  • Alan T. Critchley and
  • Balakrishnan Prithiviraj

20 October 2015

We report here the protective effects of a methanol extract from a cultivated strain of the red seaweed, Chondrus crispus, against β-amyloid-induced toxicity, in a transgenic Caenorhabditis elegans, expressing human Aβ1-42 gene. The methanol extract...

  • Article
  • Open Access
15 Citations
7,001 Views
15 Pages

20 October 2015

Sulfated polysaccharides produced by microalgae, which are known to exhibit various biological activities, may potentially serve as natural antioxidant sources. To date, only a few studies have examined the antioxidant bioactivity of red microalgal p...

  • Article
  • Open Access
54 Citations
9,428 Views
13 Pages

Assessment of the Antimicrobial Activity of Algae Extracts on Bacteria Responsible of External Otitis

  • Gianluca Pane,
  • Gabriele Cacciola,
  • Elisabetta Giacco,
  • Gian Luigi Mariottini and
  • Erika Coppo

20 October 2015

External otitis is a diffuse inflammation around the external auditory canal and auricle, which is often occurred by microbial infection. This disease is generally treated using antibiotics, but the frequent occurrence of antibiotic resistance requir...

  • Article
  • Open Access
80 Citations
7,921 Views
19 Pages

Effect of Solvent System on Extractability of Lipidic Components of Scenedesmus obliquus (M2-1) and Gloeothece sp. on Antioxidant Scavenging Capacity Thereof

  • Helena M. Amaro,
  • Fátima Fernandes,
  • Patrícia Valentão,
  • Paula B. Andrade,
  • I. Sousa-Pinto,
  • F. Xavier Malcata and
  • A. Catarina Guedes

20 October 2015

Microalgae are well known for their biotechnological potential, namely with regard to bioactive lipidic components—especially carotenoids and polyunsaturated fatty acids (PUFA), well-known for therapeutic applications based on their antioxidant capac...

  • Review
  • Open Access
218 Citations
43,411 Views
23 Pages

Tetrodotoxin, an Extremely Potent Marine Neurotoxin: Distribution, Toxicity, Origin and Therapeutical Uses

  • Jorge Lago,
  • Laura P. Rodríguez,
  • Lucía Blanco,
  • Juan Manuel Vieites and
  • Ana G. Cabado

19 October 2015

Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be produced by endosymbiotic bacteria that often seem to be passed down the...

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Mar. Drugs - ISSN 1660-3397