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Marine Drugs, Volume 10, Issue 12

December 2012 - 20 articles

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Articles (20)

  • Article
  • Open Access
54 Citations
12,741 Views
24 Pages

Isolation, Structure Elucidation and Total Synthesis of Lajollamide A from the Marine Fungus Asteromyces cruciatus

  • Tobias A. M. Gulder,
  • Hanna Hong,
  • Jhonny Correa,
  • Ekaterina Egereva,
  • Jutta Wiese,
  • Johannes F. Imhoff and
  • Harald Gross

19 December 2012

The marine-derived filamentous fungus Asteromyces cruciatus 763, obtained off the coast of La Jolla, San Diego, USA, yielded the new pentapeptide lajollamide A (1), along with the known compounds regiolone (2), hyalodendrin (3), gliovictin (4), 1N-no...

  • Article
  • Open Access
39 Citations
9,653 Views
19 Pages

Induction of Apoptosis by Sinulariolide from Soft Coral through Mitochondrial-Related and p38MAPK Pathways on Human Bladder Carcinoma Cells

  • Choo-Aun Neoh,
  • Robert Y.-L. Wang,
  • Zhong-Hao Din,
  • Jui-Hsin Su,
  • Yu-Kuei Chen,
  • Feng-Jen Tsai,
  • Shun-Hsiang Weng and
  • Yu-Jen Wu

18 December 2012

Sinulariolide, an isolated compound from the soft coral Sinularia flexibilis, possesses the anti-proliferative, anti-migratory and apoptosis-inducing activities against the TSGH bladder carcinoma cell. The anti-tumor effects of sinulariolide were det...

  • Review
  • Open Access
22 Citations
9,885 Views
32 Pages

17 December 2012

Glycobiology is the study of complex carbohydrates in biological systems and represents a developing field of science that has made huge advances in the last half century. In fact, it combines all branches of biomedical research, revealing the vast a...

  • Article
  • Open Access
24 Citations
7,156 Views
9 Pages

Sesquiterpene and Acetogenin Derivatives from the Marine Red Alga Laurencia okamurai

  • Yi Liang,
  • Xiao-Ming Li,
  • Chuan-Ming Cui,
  • Chun-Shun Li,
  • Hong Sun and
  • Bin-Gui Wang

14 December 2012

In addition to 13 known compounds, four new bisabolane sesquiterpenes, okamurenes A–D (1–4), a new chamigrane derivative, okamurene E (5), and a new C12-acetogenin, okamuragenin (6), were isolated from the marine red alga Laurencia okamurai. The stru...

  • Article
  • Open Access
25 Citations
8,560 Views
20 Pages

14 December 2012

The present study investigated the photoprotective properties of an ethanol extract derived from the red alga Bonnemaisonia hamifera against ultraviolet B (UVB)-induced cell damage in human HaCaT keratinocytes. The Bonnemaisonia hamifera ethanol extr...

  • Article
  • Open Access
22 Citations
8,708 Views
15 Pages

Palyosulfonoceramides A and B: Unique Sulfonylated Ceramides from the Brazilian Zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis

  • Jose Gustavo L. Almeida,
  • Ana Isabel V. Maia,
  • Diego V. Wilke,
  • Edilberto R. Silveira,
  • Raimundo Braz-Filho,
  • James J. La Clair,
  • Leticia V. Costa-Lotufo and
  • Otília Deusdenia L. Pessoa

14 December 2012

The zoanthids Palythoa caribaeorum and Protopalythoa variabilis are among the most abundant marine species along the Brazilian coast. We now report the isolation and structure elucidation of two unprecedented sulfonylated ceramides, palyosulfonoceram...

  • Review
  • Open Access
351 Citations
19,328 Views
22 Pages

12 December 2012

Recently, the studies on the antiviral activities of marine natural products, especially marine polysaccharides, are attracting more and more attention all over the world. Marine-derived polysaccharides and their lower molecular weight oligosaccharid...

  • Article
  • Open Access
27 Citations
7,098 Views
13 Pages

Antitumor Effect of a Polypeptide Fraction from Arca subcrenata in Vitro and in Vivo

  • Xianjing Hu,
  • Liyan Song,
  • Lijiao Huang,
  • Qin Zheng and
  • Rongmin Yu

11 December 2012

Arca subcrenata Lischke is a marine traditional Chinese medicine. The study investigated the antitumor effects of P2, a polypeptide fraction from A. subcrenata, and its toxicity in vitro and in vivo. The results showed that P2 could inhibit the proli...

  • Article
  • Open Access
211 Citations
13,923 Views
16 Pages

Phlorotannin Extracts from Fucales Characterized by HPLC-DAD-ESI-MSn: Approaches to Hyaluronidase Inhibitory Capacity and Antioxidant Properties

  • Federico Ferreres,
  • Graciliana Lopes,
  • Angel Gil-Izquierdo,
  • Paula B. Andrade,
  • Carla Sousa,
  • Teresa Mouga and
  • Patrícia Valentão

10 December 2012

Purified phlorotannin extracts from four brown seaweeds (Cystoseira nodicaulis (Withering) M. Roberts, Cystoseira tamariscifolia (Hudson) Papenfuss, Cystoseira usneoides (Linnaeus) M. Roberts and Fucus spiralis Linnaeus), were characterized by HPLC-D...

  • Article
  • Open Access
13 Citations
9,463 Views
17 Pages

Promoter Trapping in Microalgae Using the Antibiotic Paromomycin as Selective Agent

  • Marta Vila,
  • Encarnación Díaz-Santos,
  • Marta De la Vega,
  • Herminia Rodríguez,
  • Ángeles Vargas and
  • Rosa León

4 December 2012

The lack of highly active endogenous promoters to drive the expression of transgenes is one of the main drawbacks to achieving efficient transformation of many microalgal species. Using the model chlorophyte Chlamydomonas reinhardtii and the paromomy...

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Mar. Drugs - ISSN 1660-3397