Int. J. Mol. Sci., Volume 21, Issue 6 (March-2 2020) – 354 articles
Cover Story (view full-size image): The dissemination of therapy-resistant glioma cancer cells into healthy brain parenchyma presents one of the greatest obstacles to curative therapy. Intensive research in the last decade, especially a multitude of expression sequencing studies, has provided a profound insight into the heterogeneity of this devastating disease. However, the interplay between tumor and surrounding cells as well as matrix components has only recently come into focus. The present review tries to summarize advances in understanding genetic as well as extrinsic mechanisms leading to GBM invasion. View this paper.
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